Catalog No.
YMB94101
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ala25-Gln180
Predicted molecular weight
20.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09535
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Insulin-like growth factor II, IGF-II, Multiplication-stimulating polypeptide, Insulin-like growth factor II, Preptin, Igf2, Igf-2
Reduced NF-κB/NLRP3/IL-18 signaling increases the protective effect of L-glutamine against LPS-induced retinal inflammation in mice: Utilization of network pharmacology and experimental validation., PMID:40513937
Multi-locus methylation analyses reveal GNAS methylation defects in three patients with the Beckwith-Wiedemann syndrome phenotype and no molecular defects in the 11p15.5 imprinted region., PMID:40490796
Unraveling the SOX11-IGF2 signaling axis in early lung development: implications for lung disease., PMID:40481144
Insulin-Like Growth Factor 2 Reverses Synaptic and Cognitive Deficits in Fetal Growth Restriction Mice., PMID:40458983
The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
Multi-omics analysis unraveling stemness features associated with oncogenic dedifferentiation in 12 cancers., PMID:40412796
Identification of Hub Genes and Pathways Associated with Ageing in Diabetic Encephalopathy Based on Transcriptome Analysis., PMID:40397335
Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche., PMID:40394007
Skeletal stem/progenitor cell-derived rather than osteoblast-derived IGF2 supports the development and homeostasis of skeletal system via STAT3., PMID:40384861
Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes., PMID:40375290
Characterizing differences in the muscle transcriptome between cattle with alternative LCORL-NCAPG haplotypes., PMID:40369436
Effect of areca nut extracts on growth performance, slaughtering performance, and meat quality of broiler chickens., PMID:40357195
Antibody reactivity in cerebrospinal fluid and serum against the insulin-insulin-like growth factor 2 (INS-IGF2) protein is associated with psychotic symptomatology in patients with schizophrenia or related psychosis., PMID:40319454
POU6F2 promotes liver metastasis of gastric adenocarcinoma by dual mechanism of transcriptional upregulation of SNAI1 and IGF2/PI3K/AKT signaling-induced conversion of hepatic stellate cells into cancer-associated fibroblasts., PMID:40301686
Exploring hyperglycemia's impact on embryonic development: Insights from the chicken embryo model., PMID:40286730
Integrated lncRNA and mRNA Transcriptome Analyses of IGF1 and IGF2 Stimulated Ovaries Reveal Genes and Pathways Potentially Associated with Ovarian Development and Oocyte Maturation in Golden Pompano (Trachinotus ovatus)., PMID:40281968
GDF10 Regulates Iron-Dependent Lipid Oxidation in Colorectal Cancer Cells Through Interaction With IGF2., PMID:40275117
Malignant Hepatoblast-Like Cells Sustain Stemness via IGF2-Dependent Cholesterol Accumulation in Hepatoblastoma., PMID:40271711
Calf Fitness Associates with Early Embryo and Recipient Metabolomes and with Calf Epigenetic Marks., PMID:40205722
Balancing LncRNA H19 and miR-675 Bioconversion as a Key Regulator of Embryonic Myogenesis Under Maternal Obesity., PMID:40162559
IGF2BP3 As a Prognostic Biomarker and Regulator of Metastasis in Merkel Cell Carcinoma., PMID:40162116
A validated liquid chromatography-tandem mass spectrometry assay for simultaneous quantitation of intact IGF-1 and IGF-2 in human serum., PMID:40158466
Static training improves insulin resistance in skeletal muscle of type 2 diabetic mice via the IGF-2/IGF-1R pathway., PMID:40148427
IGF2-Reprogrammed Macrophages Ameliorate the Inflammatory Response and Protect Against the Neuroinflammatory Process in Parkinson's Disease Models., PMID:40146621
The Insulin-like Growth Factor Family as a Potential Peripheral Biomarker in Psychiatric Disorders: A Systematic Review., PMID:40141202
Molecular epidemiological study of exosomes circZNF609, circPUM1, IGF2 with ischemic stroke., PMID:40133811
Associations between Serum Insulin-Like Growth Factor-Related Molecules and Colorectal Cancer Risk by Tumor Location: A Nested Case-Control Study., PMID:40132573
Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19., PMID:40121473
Insulin‑like growth factor 2 in spermatogenesis dysfunction (Review)., PMID:40116127
Insulin-like growth factor 2 as a driving force for exponential expansion and differentiation of the neonatal thymus., PMID:40110795
An obesogenic FTO allele causes accelerated development, growth and insulin resistance in human skeletal muscle cells., PMID:40055326
Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas., PMID:40038716
Exploring the Plasma Proteome: Identifying Hub Proteins linking Aging, Homeostasis, and Organ Function., PMID:40027189
The IGF2BP1 oncogene is a druggable m6A-dependent enhancer of YAP1-driven gene expression in ovarian cancer., PMID:40008228
Bacillus velezensis FiA2 as an Oxydifficidin-Producing Strain and its Effects on the Growth Performance, Immunity, Intestinal Microbiota, and Resistance to Aeromonas salmonicida Infection in Carassius carassius., PMID:40000551
Insulin-Like Growth Factor 2 Secreted from Mesenchymal Stem Cells with High Glutathione Levels Alleviates Osteoarthritis via Paracrine Rejuvenation of Senescent Chondrocytes., PMID:39990979
Oxidative phosphorylation-related genes for prognosis and tumor microenvironment in breast cancer., PMID:39974386
Engineering IGF2 for Lysosome-targeting chimeras development to target drug-resistant membrane proteins in tumor therapy., PMID:39969096
Proteomic evaluation of borosilicate hybrid sol-gel coatings with osteogenic, immunomodulatory and antibacterial properties., PMID:39956001
Deciphering Sperm-Carried IGF2 Transcript Variants: Cloning, qPCR Detection, and Variant Analysis., PMID:39950974
Embryo vitrification impacts learning and spatial memory by altering the imprinting genes expression level in the mouse offspring' hippocampus., PMID:39948414
Nonislet Cell Tumor Hypoglycemia: A Rare Paraneoplastic Syndrome., PMID:39928008
The differential diagnosis of adrenocortical tumors: systematic review of Ki-67 and IGF2 and meta-analysis of Ki-67., PMID:39890749
Spectrum and carcinogenic properties of thyroglobulin gene fusions in thyroid., PMID:39878559
Effect of selenium on the dysfunction of rat salivary glands induced by 131I and expression of insulin-like growth factors and aquaporins., PMID:39838869
Role of insulin-like growth factor-2 in Alzheimer's disease induced memory impairment and underlying mechanisms., PMID:39830039
Adrenomedullin 2 attenuates anxiety-like behaviors by increasing IGF-II in amygdala and re-establishing blood-brain barrier., PMID:39809730
A comparative study of the genetically improved Abbassa Nile tilapia strain (GIANT-G9) and a commercial strain in Egypt: growth vs. stress response., PMID:39808210
Aluminum Induces Neurotoxicity through the MicroRNA-98-5p/Insulin-like Growth Factor 2 Axis., PMID:39804702
Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma., PMID:39799319
For research use only. Not for human or drug use.
