Device-free isolation of photoreceptor cells from patient iPSC-derived retinal organoids., PMID:40504625
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV., PMID:40373766
Inhibiting atrial natriuretic peptide clearance reduces myocardial fibrosis and improves cardiac function in diabetic rats., PMID:40201591
PET Imaging Expedites Detection of Aberration in the Humanization of an Annexin A1 Targeting Antibody., PMID:40143074
Clinical Scaleup of Humanized AnnA1 Antibody Yielded Unexpected High Reticuloendothelial (RES) Uptake in Mice., PMID:39982229
The α1- and β1-Subunits of Nitric Oxide-Sensitive Guanylyl Cyclase in Pericytes of Healthy Human Dental Pulp., PMID:39795887
Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA-Seq Analysis., PMID:39708312
Development and validation of a VP7-specific EIA for determining the potency and stability of inactivated rotavirus vaccine., PMID:39608463
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV., PMID:39464103
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics., PMID:39395381
Bioreactor on a chip: a microfluidic device for closed production of human dendritic cells., PMID:39269402
Preclinical evaluation of a fully human, quadrivalent-hantavirus polyclonal antibody derived from a non-human source., PMID:39258903
The BCR::ABL1 tyrosine kinase inhibitors ponatinib and nilotinib differentially affect endothelial angiogenesis and signalling., PMID:39009935
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology., PMID:38945278
Vaccination with a Human Papillomavirus L2 Multimer Provides Broad Protection against 17 Human Papillomavirus Types in the Mouse Cervicovaginal Challenge Model., PMID:38932417
Use of Transient Transfection for cGMP Manufacturing of eOD-GT8 60mer, a Self-Assembling Nanoparticle Germline-Targeting HIV-1 Vaccine Candidate., PMID:38931864
Induction of cGMP-mediated migraine attacks is independent of CGRP receptor activation., PMID:38850034
Dynamic optimization of an integrated cultivation-aggregation model for mAb production., PMID:38822680
A modular and multi-functional purification strategy that enables a common framework for manufacturing scale integrated and continuous biomanufacturing., PMID:38494903
BASIS: BioAnalysis SEDFIT integrated software for cGMP analysis of SV-AUC data., PMID:38329496
Influence of Nano-Particulate Impurities and β-glucans on the Stability of Protein-Based Formulations., PMID:38299274
Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders., PMID:38270120
Association between PRKG1 gene and gene-environment interactions with pediatric asthma., PMID:38193459
Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6., PMID:38159849
Signaling pathways upregulating glutathione‑specific γ‑glutamylcyclotransferase 1 by 3‑(5'‑hydroxymethyl‑2'‑furyl)‑1‑benzylindazole., PMID:37772365
GMP manufacture of Shigella flexneri 2a Artificial Invaplex (InvaplexAR) and evaluation in a Phase 1 Open-label, dose escalating study administered intranasally to healthy, adult volunteers., PMID:37666695
Characterizing the Protein Isoforms of foraging (for), the PKGI Ortholog in Drosophila melanogaster., PMID:37373366
T-Cell Engagers in Solid Cancers-Current Landscape and Future Directions., PMID:37345160
SATISFY-JP, a phase II multicenter open-label study on Satralizumab, an anti-IL-6 receptor antibody, use for the treatment of pulmonary arterial hypertension in patients with an immune-responsive-phenotype: Study protocol., PMID:37342675
Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control., PMID:37057828
How do we assess batch-to-batch consistency between extracellular vesicle products?, PMID:36329638
Analytical Performance Evaluation of Identity, Quality-Attribute Monitoring and new Peak Detection in a Platform Multi-Attribute Method Using Lys-C Digestion for Characterization and Quality Control of Therapeutic Monoclonal Antibodies., PMID:36279953
Changes in the expression of drug-metabolising enzymes and drug transporters in mice with collagen antibody-induced arthritis., PMID:36278306
Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants., PMID:36044897
Lanthanide-Nucleotide Coordination Nanoparticles for STING Activation., PMID:36037283
Laminin Receptor-Mediated Nanoparticle Uptake by Tumor Cells: Interplay of Epigallocatechin Gallate and Magnetic Force at Nano-Bio Interface., PMID:35893779
The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model., PMID:35881640
Function of IRAG2 Is Modulated by NO/cGMP in Murine Platelets., PMID:35743138
Sildenafil-Induced Revascularization of Rat Hindlimb Involves Arteriogenesis through PI3K/AKT and eNOS Activation., PMID:35628350
Translational development of a tumor junction opening technology., PMID:35562182
From Concept to Clinical Product: A Brief History of the Novel Shigella Invaplex Vaccine's Refinement and Evolution., PMID:35455297
A G-Protein-Coupled Receptor Modulates Gametogenesis via PKG-Mediated Signaling Cascade in Plasmodium berghei., PMID:35404079
Adenosine diphosphate-induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t-PAPS): Role of P2Y12 -cAMP signaling pathway., PMID:35395698
Prkg2 regulates alveolar type 2-mediated re-alveolarization., PMID:35313961
Characterization and Stabilization of a New 64Cu-Labeled Anti-EGFR Antibody NCAB001 for the Early Detection of Pancreatic Cancer with Positron Emission Tomography., PMID:35056963
Continuous background correction of refractive index signal to improve monoclonal antibody concentration monitoring during UF/DF and SPTFF operations., PMID:34989873
Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception., PMID:34815336
Rapid cGMP manufacturing of COVID-19 monoclonal antibody using stable CHO cell pools., PMID:34796474
Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates., PMID:34681174
Preclinical development of a Pfs230-Pfs48/45 chimeric malaria transmission-blocking vaccine., PMID:34642303