Catalog No.
EVV33901
Expression system
Mammalian Cells
Species
Measles virus (strain Edmonston-AIK-C vaccine) (MeV)
Protein length
Arg59-Arg617
Predicted molecular weight
65.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35971
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hemagglutinin glycoprotein, H
The Efficacy of Targeted Monoclonal IgA Antibodies Against Pancreatic Ductal Adenocarcinoma., PMID:40358156
Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering., PMID:40192292
Syncytial therapeutics: Receptor-specific and direct-to-cytosol biologic drug delivery mediated by measles fusion complex., PMID:39956393
The measles virus matrix F50S mutation from a lethal case of subacute sclerosing panencephalitis promotes receptor-independent neuronal spread., PMID:39641619
Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination., PMID:39046448
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies., PMID:38981470
Galactic Cosmic Ray Particle Exposure Does Not Increase Protein Levels of Inflammation or Oxidative Stress Markers in Rat Microglial Cells In Vitro., PMID:38892109
Interaction of the Hemagglutinin Stalk Region with Cell Adhesion Molecule (CADM) 1 and CADM2 Mediates the Spread between Neurons and Neuropathogenicity of Measles Virus with a Hyperfusogenic Fusion Protein., PMID:37166307
Recombinant measles virus expressing prefusion spike protein stabilized by six rather than two prolines is more efficacious against SARS-CoV-2 infection., PMID:36941778
MERS virus spike protein HTL-epitopes selection and multi-epitope vaccine design using computational biology., PMID:36935104
Infection of Pro- and Anti-Inflammatory Macrophages by Wild Type and Vaccine Strains of Measles Virus: NLRP3 Inflammasome Activation Independent of Virus Production., PMID:36851476
Cerebral Cortical Encephalitis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease., PMID:36372941
Identification and Characterization of ACP-5862, the Major Circulating Active Metabolite of Acalabrutinib: Both Are Potent and Selective Covalent Bruton Tyrosine Kinase Inhibitors ., PMID:36310034
Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant., PMID:35576833
Novel Roles of the Nipah Virus Attachment Glycoprotein and Its Mobility in Early and Late Membrane Fusion Steps., PMID:35506666
Evaluation of the effect of maternally derived antibody on response to MMR vaccine in Thai infants., PMID:35135700
Robust envelope exchange platform for oncolytic measles virus., PMID:35104497
Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice., PMID:34907710
Short-Stalk Isoforms of CADM1 and CADM2 Trigger Neuropathogenic Measles Virus-Mediated Membrane Fusion by Interacting with the Viral Hemagglutinin., PMID:34788082
TNF-α Carried by Plasma Extracellular Vesicles Predicts Knee Osteoarthritis Progression., PMID:34691080
Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine., PMID:34192426
Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins., PMID:33948566
CADM1 and CADM2 Trigger Neuropathogenic Measles Virus-Mediated Membrane Fusion by Acting in cis., PMID:33910952
MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum., PMID:33534834
Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity., PMID:33477492
Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain., PMID:32647825
Weak cis and trans Interactions of the Hemagglutinin with Receptors Trigger Fusion Proteins of Neuropathogenic Measles Virus Isolates., PMID:31619560
BST2/Tetherin Overexpression Modulates Morbillivirus Glycoprotein Production to Inhibit Cell-Cell Fusion., PMID:31366072
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins., PMID:31357579
Trans-endocytosis elicited by nectins transfers cytoplasmic cargo, including infectious material, between cells., PMID:31331966
Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice., PMID:30560893
Analysis of a Subacute Sclerosing Panencephalitis Genotype B3 Virus from the 2009-2010 South African Measles Epidemic Shows That Hyperfusogenic F Proteins Contribute to Measles Virus Infection in the Brain., PMID:30487282
Primary resistance mechanism of the canine distemper virus fusion protein against a small-molecule membrane fusion inhibitor., PMID:30296457
Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential., PMID:30232185
Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering., PMID:29997204
Promotion of virus assembly and organization by the measles virus matrix protein., PMID:29712906
Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation., PMID:29273797
Nectin-4 Interactions Govern Measles Virus Virulence in a New Model of Pathogenesis, the Squirrel Monkey (Saimiri sciureus)., PMID:28331086
[Measles Virus]., PMID:29593149
CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1., PMID:27221212
Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells., PMID:27194761
Measles Virus Fusion Protein: Structure, Function and Inhibition., PMID:27110811
A priming dose of protons alters the early cardiac cellular and molecular response to (56)Fe irradiation., PMID:26948008
Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM., PMID:26608324
Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process., PMID:25946112
Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from rheumatoid arthritis patients., PMID:25879761
Measles virus glycoprotein complexes preassemble intracellularly and relax during transport to the cell surface in preparation for fusion., PMID:25392208
Different roles of the three loops forming the adhesive interface of nectin-4 in measles virus binding and cell entry, nectin-4 homodimerization, and heterodimerization with nectin-1., PMID:25275122
The measles virus hemagglutinin stalk: structures and functions of the central fusion activation and membrane-proximal segments., PMID:24648460
Molecular determinants defining the triggering range of prefusion F complexes of canine distemper virus., PMID:24371057