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InVivoMAb Anti-Human RAGE/AGER Antibody (4E5#)

Catalog #:   VHH01903 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FuncS
Accession: Q15109
Overview

Catalog No.

VHH01903

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q15109

Applications

ELISA, FuncS

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

4E5#

Data Image
  • SDS-PAGE
    SDS PAGE for RAGE/AGER Antibody
References

Type 1 diabetes mellitus prevention: present and future., PMID:40527975

Anti-CD14 treatment in patients with severe COVID-19: Clinical and biological effects in a Phase 2 randomized open-label adaptive platform clinical trial., PMID:40462830

Clinical significance of serum RAGE levels in anti-CCP-negative rheumatoid arthritis., PMID:40402318

Sterile Inflammation and Cell Death Pathways in Liver Ischemia-Reperfusion Injury: A Review and Perspective., PMID:40396312

HMGB1 derived from macrophages and enteric glial cells contributes to the butyrate-induced colonic hypersensitivity in mice., PMID:40274181

Integrated renin angiotensin system dysregulation and immune profiles predict COVID-19 disease severity in a South African cohort., PMID:40229302

Development of novel neutralizing single-chain fragment variable antibodies against S100A8., PMID:40221535

Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients., PMID:40187358

Extracellular vesicle-bound S100A8/A9 is differentially expressed in septic shock and prompts acute lung injury., PMID:40102943

Highlights from the breakout session: vasculitis in paediatric rheumatology., PMID:40071400

E-twenty-six-specific sequence variant 5 (ETV5) facilitates hepatocellular carcinoma progression and metastasis through enhancing polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC)-mediated immunosuppression., PMID:40015948

Functional Characterization of Glycated Peptide Aggregates in Whey Protein Hydrolysates., PMID:39974509

An anti-RAGE chimeric antibody alleviates CCl4-induced liver fibrosis via RAGE/NF-kB pathway in mice., PMID:39657505

Membrane-bound receptor for advanced glycation end products (RAGE) is a stable biomarker of low-quality sperm., PMID:39553285

Functional modulation of RAGE activation by multimeric S100B using single-domain antibodies., PMID:39542249

Extracellular RIPK3 Acts as a Damage-Associated Molecular Pattern to Exaggerate Cardiac Ischemia/Reperfusion Injury., PMID:39411860

Molecular dynamics simulation of the brain-isolated single-domain antibody/nanobody from camels through in vivo phage display screening., PMID:39290991

Inflammatory markers, oxidative stress, and mitochondrial dynamics: Repercussions on coronary artery disease in diabetes., PMID:39280176

Evaluation of inflammatory biomarkers and their association with anti-SARS-CoV-2 antibody titers in healthcare workers vaccinated with BNT162B2., PMID:39247198

Longitudinal importance of the soluble receptor for advanced glycation end-products in nonintubated hospitalized patients with COVID-19 pneumonia., PMID:39076084

Nematode Galectin Inhibits Basophilic Leukaemia RBL-2H3 Cells Apoptosis in IgE-Mediated Activation., PMID:39000527

Bidirectional Two-Sample Mendelian Randomization Study of Immunoglobulin G N-Glycosylation and Senescence-Associated Secretory Phenotype., PMID:38928043

The TOX-RAGE axis mediates inflammatory activation and lung injury in severe pulmonary infectious diseases., PMID:38900789

Alirocumab boosts antioxidant status and halts inflammation in rat model of sepsis-induced nephrotoxicity via modulation of Nrf2/HO-1, PCSK9/HMGB1/NF-ᴋB/NLRP3 and Fractalkine/CX3CR1 hubs., PMID:38889644

Does glucose-dependent insulinotropic polypeptide receptor blockade as well as agonism have a role to play in management of obesity and diabetes?, PMID:38861364

Effect of antibody-mediated connective tissue growth factor neutralization on lung edema in ventilator-induced lung injury in rats., PMID:38778274

Tick-borne zoonotic flaviviruses and Borrelia infections in wildlife hosts: What have field studies contributed?, PMID:38746540

Berberine Improves Cancer-Derived Myocardial Impairment in Experimental Cachexia Models by Targeting High-Mobility Group Box-1., PMID:38731953

Nε-carboxymethyl-lysine and inflammatory cytokines, markers and mediators of coronary artery disease progression in diabetes., PMID:38680703

Insight into the Interplay of Gd-IgA1, HMGB1, RAGE and PCDH1 in IgA Vasculitis (IgAV)., PMID:38673968

Prevention of colon enlargement by TNF-α antagonist in a streptozotocin-induced diabetic rat model., PMID:38572731

The TGF-β/MMP9/RAGE axis induces sRAGE secretion by neutrophils and promotes oral carcinogenesis., PMID:38463640

Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1:RAGE signaling and reversed by increased LAIR-1 expression., PMID:38448779

Tissue-resident macrophages exacerbate lung injury after remote sterile damage., PMID:38228746

Targeting the heparan sulfate-binding site of RAGE with monoclonal antibodies., PMID:38181393

Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models., PMID:38180084

Targeting TAM-secreted S100A9 effectively enhances the tumor-suppressive effect of metformin in treating lung adenocarcinoma., PMID:38008395

Inflammatory Cytokine Elaboration Following Secondhand Smoke (SHS) Exposure Is Mediated in Part by RAGE Signaling., PMID:37958629

[Altered expression of 15-hydroxyprostaglandin dehydrogenase in chronic rhinosinusitis with nasal polyps]., PMID:37905483

Design of an Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy., PMID:37844138

HMGB1-RAGE axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte autophagy and apoptosis in diabetic mice., PMID:37768929

Could anionic LDL be a ligand for RAGE and TREM2 in addition to LOX-1 and thus exacerbate lung disease and dementia?, PMID:37544530

Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms., PMID:37533998

Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice., PMID:37443823

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex., PMID:37442582

The soluble receptor for advanced glycation end products is potentially predictive of pulmonary arterial hypertension in systemic sclerosis., PMID:37409127

A specific RAGE-binding peptide inhibits triple negative breast cancer growth through blocking of Erk1/2/NF-κB pathway., PMID:37380046

Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction., PMID:37330528

Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling., PMID:37292843

Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction., PMID:37156450

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human RAGE/AGER Antibody (4E5#) [VHH01903]
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