Catalog No.
YVV15601
Expression system
E. coli
Species
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Protein length
Tyr18-His279
Predicted molecular weight
31.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01227
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein OPG190, Plaque-size/host range protein, OPG190, PS/HR, VACWR187, B5R
ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping., PMID:25630650
Identification of 10 cowpox virus proteins that are necessary for induction of hemorrhagic lesions (red pocks) on chorioallantoic membranes., PMID:24850732
Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies., PMID:23133652
Sequence and phylogenetic analysis of host-range (E3L, K3L, and C7L) and structural protein (B5R) genes of buffalopox virus isolates from buffalo, cattle, and human in India., PMID:22872567
Modulation of the myxoma virus plaque phenotype by vaccinia virus protein F11., PMID:22514354
Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge., PMID:21885079
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model., PMID:20587859
Investigation of orf virus structure and morphogenesis using recombinants expressing FLAG-tagged envelope structural proteins: evidence for wrapped virus particles and egress from infected cells., PMID:19218206
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement., PMID:19019965
Targeting the vaccinia virus L1 protein to the cell surface enhances production of neutralizing antibodies., PMID:18485547
B5r gene based sequence analysis of Indian buffalopox virus isolates in relation to other orthopoxviruses., PMID:17432943
Human T-cell responses to vaccinia virus envelope proteins., PMID:17005679
Subunit recombinant vaccine protects against monkeypox., PMID:16888017
Vaccinia virus intracellular enveloped virions move to the cell periphery on microtubules in the absence of the A36R protein., PMID:16227217
Differential efficacy of vaccinia virus envelope proteins administered by DNA immunisation in protection of BALB/c mice from a lethal intranasal poxvirus challenge., PMID:15308360
Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates., PMID:12620810