Catalog No.
EHJ81301
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Glu490-Arg566
Predicted molecular weight
37.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UMD9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Linear IgA disease antigen 1, COL17A1, 180 kDa bullous pemphigoid antigen 2, LAD-1, Linear IgA bullous disease antigen of 97 kDa, 120 kDa linear IgA dermatosis antigen, 97-LAD, Collagen alpha-1(XVII) chain, Bullous pemphigoid antigen 2, 97 kDa linear IgA bullous dermatosis antigen, LABD97, 97 kDa LAD antigen, BPAG2, BP180
Evaluation of tumor targets selected from public genomic databases for imaging of pancreatic ductal adenocarcinoma., PMID:40379788
Identifying six single nucleotide variants in the COL17A1 gene that alter RNA splicing: database analysis and minigene assays., PMID:40181146
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII., PMID:40066849
Novel strategy for hair regeneration: Exosomes and collagenous sequences of human a1(XVII) chain enhance hair follicle stem cell activity by regulating the hsa-novel-238a-CASP9 axis., PMID:40010561
Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4., PMID:39907925
ADAM10 Expression by Ameloblasts Is Essential for Proper Enamel Formation., PMID:39684894
Non-Herlitz junctional epidermolysis bullosa in a Native American newborn., PMID:39636096
Caviar extract inhibits skin photoaging by activating skin stem cells through NF-κB/MMPs/COL17A1 axis., PMID:39627162
Construction of a novel model based on PVT1-MYC duet-related genes for predicting survival and characterization of the tumor microenvironment in pancreatic cancer., PMID:39376555
Expression, DNA methylation pattern and transcription factor EPB41L3 in gastric cancer: a study of 262 cases., PMID:39354571
Junctional Epidermolysis Bullosa in Sprague Dawley Rats Caused by a Frameshift Mutation of Col17a1 Gene., PMID:39265891
Heterozygous COL17A1 variants are a frequent cause of amelogenesis imperfecta., PMID:39214682
The Deubiquitinase USP22-Stabilized COL17A1 Promotes Lung Adenocarcinoma Progression., PMID:39143031
[Clinical and bioinformatics analysis of the relationship between LAMA3 DNA methylation expression and platinum resistance and prognosis in epithelial ovarian cancer]., PMID:38951081
[A case of Neonatal generalized atrophic benign epidermolysis bullosa due to variants of COL17A1 gene]., PMID:38818561
Collagen XVII promotes dormancy of colorectal cancer cells by activating mTORC2 signaling., PMID:38795810
Collagen 17A1 in the Urothelium Regulates Epithelial Cell Integrity and Local Immunologic Responses in Obstructive Uropathy., PMID:38768778
Dab2 (Disabled-2), an adaptor protein, regulates self-renewal of hair follicle stem cells., PMID:38702433
The Molecular Characteristics and Therapeutic Implications of O-Glycan Synthesis in Pancreatic Cancer by Integrating Transcriptome and Single-Cell Data., PMID:38659264
Strategy for the Optimization of Read-Through Therapy for Junctional Epidermolysis Bullosa with COL17A1 Nonsense Mutation., PMID:38522573
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells., PMID:38459694
Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment., PMID:38401525
IC3D Classification of Corneal Dystrophies-Edition 3., PMID:38359414
Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions., PMID:38317805
NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1., PMID:38175757
Genotype-Phenotype Correlation in Junctional Epidermolysis Bullosa: Signposts to Severity., PMID:38157931
Heterozygous COL17A1 variants are a frequent cause of amelogenesis imperfecta., PMID:37979963
METTL14-mediated N6-methyladenosine modification of Col17a1/Itgα6/Itgβ4 governs epidermal homeostasis., PMID:37951776
Digenic inheritance accounts for phenotypic variability in amelogenesis imperfecta., PMID:37937686
Independent COL17A1 Variants in Cats with Junctional Epidermolysis Bullosa., PMID:37895184
Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum., PMID:37883475
Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice., PMID:37796769
Collagen XVII regulates tumor growth in pancreatic cancer through interaction with the tumor microenvironment., PMID:37688308
Molecular insights of human skin epidermal and dermal aging., PMID:37661473
Bazi Bushen alleviates skin senescence by orchestrating skin homeostasis in SAMP6 mice., PMID:37614114
Identification of potential hub genes associated with atopic dermatitis-like recombinant human epidermal model using integrated transcriptomic and proteomic analysis., PMID:37540585
Native Autoantigen Complex Detects Pemphigoid Autoantibodies., PMID:36992950
A Novel Fluorescence-Based Screen of Gene Editing Molecules for Junctional Epidermolysis Bullosa., PMID:36982270
Mutational analysis of epidermolysis bullosa in Taiwan by whole-exome sequencing complemented by RNA sequencing: a series of 77 patients., PMID:36578049
ADAM10: Possible functions in enamel development., PMID:36505044
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization., PMID:36435441
Targeted NGS in Diagnostics of Genodermatosis Characterized by the Epidermolysis Bullosa Symptom Complex in 268 Russian Children., PMID:36430820
Dipeptidyl Peptidase-4 Inhibitor-Related Bullous Pemphigoid: Clinical, Laboratory, and Histological Features, and Possible Pathogenesis., PMID:36430582
Genotype and phenotype correlations in 441 patients with epidermolysis bullosa from China., PMID:36287101
A necroptosis related prognostic model of pancreatic cancer based on single cell sequencing analysis and transcriptome analysis., PMID:36275722
COL17A1 facilitates tumor growth and predicts poor prognosis in pancreatic cancer., PMID:36191371
COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa., PMID:36091706
Palmitoyl‑RGD promotes the expression of dermal‑epidermal junction components in HaCaT cells., PMID:36043531
Absence of NC14A Domain of COLXVII/BP180 in Mice Results in IL-17‒Associated Skin Inflammation., PMID:35985497
Bioinformatics Analysis Identifies Potential Related Genes in the Pathogenesis of Intrauterine Fetal Growth Retardation., PMID:35923419
For research use only. Not for human or drug use.
