Catalog No.
YHF45101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Gly189
Predicted molecular weight
26.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61586
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Rho cDNA clone 12, ARH12, RHO12, ARHA, RHOA, Transforming protein RhoA, h12
RhoA GAP Myo9b regulates β2-integrin activity and neutrophil recruitment during murine acute kidney injury., PMID:40504998
Lysophosphatidic acid and sphingosine-1-phosphate are apical polarity cues in multiple organoid systems., PMID:40503936
S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis., PMID:40495705
ARC Expands the DAAM1 Microexon-Mediated Actin-RHOA/ROCK Interplay., PMID:40488380
Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke., PMID:40481713
RAP1-RHO small GTPase cross-talk mediates integrin-dependent and - independent platelet procoagulant response., PMID:40475636
Association of RhoGEF Ect2 with Desmoplakin Supports RhoA Activity at Intercellular Junctions: Implications for Carvajal Disease., PMID:40475587
Polycystin-1 acts as an atypical adhesion GPCR that responds to novel Wnt signaling and mechanical stimuli., PMID:40475421
Control of epithelial tissue organization by mRNA localization., PMID:40473627
RhoA Interacts With TPM4 to Promote Myofascial Trigger Point Pain in Rats via the ERK Signaling Pathway., PMID:40464545
Mechanistic Insights into GTP Hydrolysis by the RhoA Protein: Catalytic Impact of Glutamine Tautomerism., PMID:40463518
Epithelial eversion, a collective rearrangement from apical-in to apical-out polarity, is initiated by α6β4 integrins and sustained by increased cell proliferation and anchorage-independence., PMID:40463241
Nitric oxide regulates spindle dynamics to modulate the maturation of goat oocytes., PMID:40460471
Biological characteristics of spontaneous ovarian cancer in Microtusfortis., PMID:40457786
Muscone Reduces OGD/R-Induced Hyperpermeability of the Brain Endothelial Barrier by Activating the PKA/RHOA/MLC Pathway., PMID:40454512
Advances in the Pathophysiology of Thin Endometrium., PMID:40447929
Nonylphenol exposure induces myocardial fibrosis via the RhoA/ROCK1/MLC-signaling pathway., PMID:40446736
Renal Dysfunction Induced by Sodium p-Perfluorous Nonenoxybenzenesulfonate in Mice: Insights from the Intrinsic Mechanisms of Proteinuria., PMID:40444664
GPR56/ADGRG1 induces biased Rho-ROCK-MLC and JAK-STAT3 signaling to promote amoeboid-like morphology and IL-6 upregulation in melanoma cells., PMID:40442782
Tear Proteomic Analysis From Offspring of Keratoconus Patients: New Insights Into Corneal Biomechanical Weakness and Disease Risk Stages., PMID:40434347
BDNF/proBDNF Interplay in the Mediation of Neuronal Apoptotic Mechanisms in Neurodegenerative Diseases., PMID:40430064
YAP controls cell migration and invasion through a Rho GTPase switch., PMID:40424361
Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion., PMID:40421714
RHOA-associated disorder can be non-mosaic., PMID:40414526
Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway., PMID:40414437
Dietary addition of fraxetin improved intestinal structure and growth performance in juvenile grass carp (Ctenopharyngodon idella): as a potential novel phytogenic feed additive., PMID:40412568
Androgen receptor plays critical role in regulating cervical cancer cell migration., PMID:40409531
SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells., PMID:40402207
Negative cooperativity regulates ligand activation of DIAPH1 and other diaphanous related formins., PMID:40399622
Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis., PMID:40391947
Leucine-rich repeat-containing 56 promotes breast cancer progression via modulation of the RhoA/ROCKs signaling axis., PMID:40388100
PRRG4 Brain-Specific Conditional Knockout Mice Display Autism Spectrum Disorder-Like Behaviors., PMID:40380139
Activation of G protein-coupled estrogen receptor alleviates the abnormal changes of synaptic plasticity in the anterior insula of temporal lobe epilepsy rats through RhoA/Rock2 pathway., PMID:40373909
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction., PMID:40364748
Oral Acid-Activated Hydrogen-Producing Nanoparticles Reduce Aortic Dissection Progression via RhoA/ROCK Inhibition in Mice., PMID:40361256
Anillin links up with RhoA to break the symmetry of cytokinetic ring closure., PMID:40353780
Norepinephrine mediates adrenergic receptor transcription and oncogenic gene expression in pancreatic ductal adenocarcinoma., PMID:40349604
Beta cells intrinsically sense and limit their secretory activity via mTORC1-RhoA signaling., PMID:40347471
Real-World Data on the p.Gly17Val RHOA Mutation in Diagnosing T Follicular Helper Cell Lymphomas., PMID:40347078
Caspase-mediated cleavage of a scaffold protein, MPRIP, yields a truncated form that is involved in repetitive bleb formation., PMID:40344468
TMEM16A Maintains Acrosomal Integrity Through ERK1/2, RhoA, and Actin Cytoskeleton During Capacitation., PMID:40332387
A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation., PMID:40328765
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins., PMID:40327382
The Rho GEF Trio functions in contact inhibition of locomotion of neural crest cells by interacting with Ptk7., PMID:40326503
MAGI1 attenuates osteoarthritis by regulating osteoclast fusion in subchondral bone through the RhoA-ROCK1 signaling pathway., PMID:40322041
Hypoandrogenic state inhibits erectile function in rats via miR-200a-3p., PMID:40319342
Lead exposure disrupts cytoskeletal arrangement and perturbs glucose metabolism in nerve cells through activation of the RhoA/ROCK signaling pathway., PMID:40315746
From cause to relief: Vitamin D plays a crucial role in overactive bladder via the RhoA/ROCK signaling pathway., PMID:40311294
A cortical pool of LIN-5 (NuMA) controls cytokinetic furrow formation and cytokinesis completion., PMID:40304693
Role of membrane proximal actin regulators in SARS-CoV-2 spike-induced cell-cell fusion., PMID:40300332
For research use only. Not for human or drug use.
