Catalog No.
YHD59402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His129-Arg247
Predicted molecular weight
17.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23560
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ProBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF
Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress., PMID:40517150
From neurotoxicity to neuroprotection: Rethinking GABAAR-targeting anesthetics., PMID:40516005
Arecoline Alleviates Autism Spectrum Disorder-like Behaviors and Cognition Disorders in a Valproic Acid Mouse Model by Activating the AMPK/CREB/BDNF Signaling Pathway., PMID:40513625
Cross-sectional association between brain-derived neurotrophic factor and intrinsic capacity in older adults: The mediating role of oxidative stress., PMID:40513379
Adropin ameliorates behavioral seizures and the relevant neuroinflammation, oxidative stress, and neural damage in a rat model of pentylenetetrazole-induced seizure potentially by reducing the activation of NF-κB/IkB-α signaling pathway., PMID:40512435
Anxiolytic Effects of Cichorium intybus L. Oligo-Polysaccharides by Modulating Gut Microbiota, Neuronal Signaling Pathways, and Neuroinflammation in Chronic Sleep Deprivation-Stressed Mice., PMID:40509387
Identification of Plasma Growth Factors and Cytokines as Diagnostic Biomarkers for the Lafora Form of Progressive Myoclonus Epilepsy., PMID:40508163
Niacin Modulates SIRT1-Driven Signaling to Counteract Radiation-Induced Neurocognitive and Behavioral Impairments., PMID:40508105
Investigating acupuncture therapy in depression: mechanisms of synaptic plasticity regulation., PMID:40506009
Therapeutic Role of l-Theanine in Mitigating Cognitive Dysfunction and Neuropathology in Scopolamine-Treated Mice., PMID:40504752
The Role of Epigenetics in Manganese Neurotoxicity: An Update with a Focus on Non-Coding RNAs and Histone Modifications., PMID:40498345
Agonism of MT1 and MT2 Receptor Mitigates Oxidative Insult, Neuroinflammation, and Cerebral Injury in Cadmium Chloride Treated Animals., PMID:40493137
Altered Neuroplasticity in Epilepsy is Associated with Neuroinflammation and Oxidative Stress: In vivo Evidence of Brain-Derived Extracellular Vesicles., PMID:40491852
The physiopathology of brain-derived neurotrophic factor., PMID:40490314
Targeting neurotrophic dysregulation in diabetic retinopathy: a novel therapeutic avenue., PMID:40488922
Supplementation of Omega-3 Increases Serum Levels of Brain-Derived Neurotrophic Factor and Decreases Depression Status in Patients With Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial., PMID:40485144
Impact of mild prenatal LPS-induced inflammation and postnatal stress on synaptic plasticity and neuroimmune responses in the prefrontal cortex of adult male mice., PMID:40482402
Maternal high-fat diet impairs cognitive performance by altering hippocampal GRP78/PERK axis and BDNF expression in adult female rat offspring: the potential protective role of N acetylcysteine., PMID:40481912
Physiological and psychological responses to five-day fasting., PMID:40479627
Graptophyllum grandulosum Prevents Nicotine Addiction in Pubescent Adolescent Rats: Evidence on Dopaminergic, Cholinergic, BDNF and Neuroinflammatory Pathways., PMID:40478356
Advances in research on the pathogenesis and signaling pathways associated with postoperative delirium (Review)., PMID:40476568
Dim light at night induces depression-like behaviors during the postpartum period through circadian rhythm related pathways in mice., PMID:40473593
Puerarin suppresses the oxidative stress and activates the cyclic AMP (cAMP)/cAMP response element binding protein/brain-derived neurotrophic factor signaling pathway in alcohol withdrawal-induced depressive disorder via regulating obesity-associated protein-mediated N6-methyladenosine demethylation., PMID:40470634
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease., PMID:40468230
Analysis of the diagnostic accuracy of plasma sTNFr-2 concentrations in identifying sarcopenia in community-dwelling older women., PMID:40468004
Immediate and short-term effect of physical exercise on BDNF in multiple sclerosis patients: a systematic review and meta-analysis., PMID:40467854
Playback of ultrasonic vocalisations (38-48 kHz) communicates the state of stress and impaired context episodic memory in adolescent rats., PMID:40466931
Technical report: Efficient and accurate assessment of neurite outgrowth in spiral ganglion explants using Sholl analysis and repeated measurement ANOVA., PMID:40465765
Neuroprotective Effect of PBCA Nanoparticles Delivering pEGFP-BDNF in a Mouse Model of Intracerebral Hemorrhage., PMID:40464471
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA., PMID:40460907
Cancer-Related Cognitive Impairment in Patients With Lung Cancer., PMID:40460355
BDNF gene polymorphisms and BDNF serum concentration in schizophrenia patients: a pilot study., PMID:40458783
Glial inwardly rectifying potassium channel 4.1 regulates secretion of BDNF and GDNF via ERK1/2 MAP kinases in trigeminal neuropathic pain., PMID:40456346
Trauma, Epigenetic Alterations, and Psychotherapy., PMID:40454823
Serotoninergic modulation in the brainstem and hypothalamus of female overnourished rats: impact on mitochondrial markers, oxidative stress and BDNF mRNA levels., PMID:40452918
High-frequency repetitive transcranial magnetic stimulation upregulates BDNF expression and promotes synaptogenesis in mouse models of Parkinson's disease., PMID:40451606
Processivity and BDNF-dependent modulation of signalling endosome axonal transport are impaired in mice with advanced age., PMID:40449249
Astrocytic HSP60 Deletion Induced Astrocyte Senescence and Inhibited Neuroregeneration via Modulating the S1P/Truncated-BDNF Pathway., PMID:40448367
Photobiomodulation therapy: Location-dependent effects on memory and recovery in male adult rats with spinal cord injury., PMID:40447286
Predicting rTMS treatment response in depression: use of machine learning models to identify the roles of metabolic and clinical factors., PMID:40447154
Gastrodia elata polysaccharide alleviates depression via gut microbiota modulation and Keap1-Nrf2/BDNF-TrkB pathway activation., PMID:40447013
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model., PMID:40446976
Kirenol alleviates cerebral ischemic injury by promoting synaptic plasticity via HDAC2-mediated BDNF expression., PMID:40446576
The Role of Periodontitis in Increasing Cognitive Decline in Alzheimer's Disease., PMID:40444562
α-linolenic acid-induced facilitation of GABAergic synaptic transmission is mediated via acid-sensing ion channel (ASIC1a) activity in the basolateral amygdala., PMID:40444142
Socioeconomic factors, brain-derived neurotrophic factor Val66Met polymorphism, and cortical structure in children and adolescents., PMID:40442425
Resveratrol attenuates prenatal X-ray-induced microcephaly and adult depression via SIRT1-mediated senescence suppression and TPH2/5-HT pathway restoration in mice., PMID:40440905
BDNF/proBDNF Interplay in the Mediation of Neuronal Apoptotic Mechanisms in Neurodegenerative Diseases., PMID:40430064
Icariin Ameliorates Cyclophosphamide-Induced Renal Encephalopathy by Modulating the NF-κB and Keap1-Nrf2 Signaling Pathways., PMID:40429978
Shed Syndecans (1-3), ELA-32, BDNF, NLR, and hs-CRP in Parkinson's Disease: Appropriate Diagnostic and Prognostic Biomarkers When Combined in a Unique Panel., PMID:40429647
For research use only. Not for human or drug use.
