Catalog No.
YHF36802
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Thr134
Predicted molecular weight
16.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60568
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor
Development of a Cell Membrane-Anchored Aptamer Sensor for IL-2 Detection In Situ., PMID:40447990
Loss of proton-sensing GPR4 reduces tumor progression in mouse models of colon cancer., PMID:40397803
Receptor-based bioassay for functional IL-2 quantification., PMID:40300311
IFN-γ/IL-2 Double-Color FluoroSpot Assay for Monitoring Human Primary T Cell Activation: Validation, Inter-Laboratory Comparison, and Recommendations for Clinical Studies., PMID:40281193
Role of IL-2, IL-6, and TNF-α as Potential Biomarkers in Ischemic Heart Disease: A Comparative Study of Patients with CAD and Non-CAD., PMID:40265387
Study of IL2-330 (rs2069762) gene polymorphism in Egyptian patients with lung cancer: a case-control study., PMID:40098465
An engineered Treg selective immunocytokine induces sustained immune modulation in a preclinical model of hemophilia A., PMID:40056981
The Diagnostic Value of Interleukin-2 and Interferon-γ Induced by Fusion Protein (ESAT-6/CFP-10/Rv1985c) for Active Mycobacterium tuberculosis Infection., PMID:40019050
Zinc Deficiency Exacerbates Lead-Induced Interleukin-2 Suppression by Regulating CREM Expression., PMID:39796118
Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network., PMID:39662679
Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-γ in human T-lymphocytes., PMID:39434339
CD38 in SLE CD4 T cells promotes Ca2+ flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane., PMID:39333474
Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation., PMID:39302339
Genetic evidence for efficacy of targeting IL-2, IL-6 and TYK2 signalling in the prevention of type 1 diabetes: a Mendelian randomisation study., PMID:39271518
Prediction of the Intra-T Lymphocyte Tacrolimus Concentration after Kidney Transplantation with Population Pharmacokinetic Modeling., PMID:39139076
IL-2, IL-17A and TNF-α hold potential as biomarkers for predicting acute mountain sickness prior to ascent., PMID:39024679
Systemic investigation of the mechanism underlying the therapeutic effect of Astragalus membranaceus in ulcerative colitis., PMID:39009282
Plasma Levels of Interleukin 2 (IL-2) Associated with Hearing Loss Evaluation in the Elderly., PMID:38904818
Association of interleukin-2 and interleukin-10 with the pathophysiology and development of generalized anxiety disorder: a case-control study., PMID:38902708
Association of CTACK, IL-2, and IL-13 with increased risk of lung cancer: A Mendelian randomization study., PMID:38885591
Soluble and insoluble expression of recombinant human interleukin-2 protein using pET expression vector in Escherichia coli., PMID:38824503
Cytokine profile in the saliva of patients with active psoriasis revealed significant upregulation of TNF-α, IFN-γ, IL-2 and downregulation of IL-10., PMID:38809371
Soluble expression of recombinant human interleukin-2 in Escherichia coli and its facile production., PMID:38777308
Genetic polymorphisms in IL-2, IL-10 and FOXP3 are associated with autoimmune neutropenia in early childhood and autoantibody specificity in a Danish cohort., PMID:38750640
Flow cytometry-based method using diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease., PMID:38739968
Killer Function of Circulating Neutrophils in Relation to Cytokines in Uterine Myoma and Endometrial Cancer., PMID:38730105
Effect of IL-2 polymorphism rs2069762 on single-unit cord blood transplant outcomes., PMID:38718489
PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function., PMID:38658764
Association between peripheral plasma cytokine levels and suicidal ideation in first-episode, drug-naïve major depressive disorder., PMID:38613945
Armed with IL-2 based fusion protein improves CAR-T cell fitness and efficacy against solid tumors., PMID:38583815
Establishment of reference intervals for plasma IL-2, IL-4, IL-5, and IL-17A in healthy adults from the Jiangsu region of eastern China using flow cytometry: A single-center study., PMID:38581867
Specific Targeting of Zinc Transporter LIV-1 with Immunocytokine Containing Anti-LIV-1 VHH and Human IL-2 and Evaluation of its In vitro Antitumor Activity., PMID:38482625
Differential requirement for IL-2 and IL-23 in the differentiation and effector functions of Th17/ILC3-like cells in a human T cell line., PMID:38374693
Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population., PMID:38195135
The soluble IL-2 receptor α/CD25 as a modulator of IL-2 function., PMID:38037265
Intestinal flora altered and correlated with interleukin-2/4 in patients with primary immune thrombocytopenia., PMID:37921501
Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response in vivo., PMID:37809101
Down-regulation of interleukin-2 predicts poor prognosis and associated with immune escape in lung adenocarcinoma., PMID:37731383
Association of Interleukin-2 Gene Polymorphism with Henoch-schönlein Purpura Nephritis., PMID:37524668
Expression analysis of IL-2, TBX21 and SOCS1 in peripheral blood cells of celiac disease patients reveals the diagnostic potential of IL-2., PMID:37039998
Pan-HDAC inhibitors augment IL2-induced proliferation of NK cells via the JAK2-STAT5B signaling pathway., PMID:36738675
The Effect of Interleukin-2 -330 T/G Polymorphism in People with Schizophrenia Among The Batak and Javanese Ethnic Groups., PMID:38299092
Exploring the association of interleukin polymorphisms with aggression and internalizing behaviors in children and adolescents., PMID:36168941
The effect of serum IL-2 levels on the prognosis of primary biliary cholangitis-related liver failure and the preliminary exploration of its mechanism., PMID:36159788
[Detection Value of EB Virus DNA, IL-2, and IL-6 Level in Peripheral Blood of Children with Infectious Mononucleosis]., PMID:35981395
IL-2, IL-6 and chitinase 3-like 2 might predict early relapse activity in multiple sclerosis., PMID:35759479
The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription., PMID:35523941
Human IL-2Rɑ subunit binding modulation of IL-2 through a decline in electrostatic interactions: A computational and experimental approach., PMID:35213635
Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients., PMID:35192617
SERUM LEVELS OF IL-2 AND IL-17A ARE RELATED TO CLINICAL TYPE AND SEVERITY OF ALOPECIA AREATA., PMID:35182133
For research use only. Not for human or drug use.
