Catalog No.
YHA64804
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn35-Arg207
Predicted molecular weight
20.41KDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43320
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF-16, Fibroblast growth factor 16, FGF16
CAUSAL ASSOCIATION BETWEEN SEPSIS AND FIBROBLAST GROWTH FACTORS AS WELL AS THEIR RECEPTORS LEVELS: A TWO-SAMPLE MENDELIAN RANDOMIZATION STUDY., PMID:40138723
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
A primer for Fibroblast Growth Factor 16 (FGF16)., PMID:39632143
[Advances in genetic research on Non-syndromic congenital joint synostosis]., PMID:39097287
Circulating inflammatory biomarkers and risk of intracranial aneurysm: a Mendelian randomization study., PMID:38173028
Reprogramming of glucose metabolism via PFKFB4 is critical in FGF16-driven invasion of breast cancer cells., PMID:37222403
Genome-Wide Identification and Characterization of Bovine Fibroblast Growth Factor (FGF) Gene and Its Expression during Adipocyte Differentiation., PMID:36982739
Mettl3-mediated m6A modification of Fgf16 restricts cardiomyocyte proliferation during heart regeneration., PMID:36399125
Transcription analysis of chicken embryo fibroblast cells infected with the recombinant avian leukosis virus isolate GX14FF03., PMID:36070017
Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response., PMID:35415885
Identification of Growth Factors, Cytokines and Mediators Regulated by Artemisia annua L. Polyphenols (pKAL) in HCT116 Colorectal Cancer Cells: TGF-β1 and NGF-β Attenuate pKAL-Induced Anticancer Effects via NF-κB p65 Upregulation., PMID:35163520
Fibroblast growth factor (FGF), FGF receptor (FGFR), and cyclin D1 (CCND1) DNA methylation in head and neck squamous cell carcinomas is associated with transcriptional activity, gene amplification, human papillomavirus (HPV) status, and sensitivity to tyrosine kinase inhibitors., PMID:34933671
Patient-specific iPSC-derived cardiomyocytes reveal abnormal regulation of FGF16 in a familial atrial septal defect., PMID:33956078
Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways., PMID:33643049
Insights into the Regulation on Proliferation and Differentiation of Stem Leydig Cells., PMID:33598893
Bone morphogenetic protein 15 supplementation enhances cumulus expansion, nuclear maturation and progesterone production of in vitro-matured bovine cumulus-oocyte complexes., PMID:33565658
Withdrawal: FGF16 promotes invasive behavior of SKOV-3 ovarian cancer cells through activation of mitogen-activated protein kinase (MAPK) signaling pathway., PMID:33310746
Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment., PMID:32973962
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control., PMID:32777030
Molecular characterization of fibroblast growth factor-16 and its role in promoting the differentiation of intramuscular preadipocytes in goat., PMID:32624066
Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells., PMID:31801200
Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells., PMID:31735119
miR-372-3p is a potential diagnostic factor for diabetic nephropathy and modulates high glucose-induced glomerular endothelial cell dysfunction via targeting fibroblast growth factor-16., PMID:37313198
DNA hypermethylation of Fgf16 and Tbx22 associated with cleft palate during palatal fusion., PMID:31596367
MiRNA-144-3p inhibits high glucose induced cell proliferation through suppressing FGF16., PMID:31292167
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes., PMID:31270389
Fibroblast growth factor 16 stimulates proliferation but blocks differentiation of rat stem Leydig cells during regeneration., PMID:30672118
Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l., PMID:32149373
Cardiac Fgf-16 Expression Supports Cardiomyocyte Survival and Increases Resistance to Doxorubicin Cytotoxicity., PMID:30230915
Secretome Screening Reveals Fibroblast Growth Factors as Novel Inhibitors of Viral Replication., PMID:29899088
Expression and purification of an FGF9 fusion protein in E. coli, and the effects of the FGF9 subfamily on human hepatocellular carcinoma cell proliferation and migration., PMID:28921304
Cellular Migration Ability Is Modulated by Extracellular Purines in Ovarian Carcinoma SKOV-3 Cells., PMID:28464260
Cardiokines as Modulators of Stress-Induced Cardiac Disorders., PMID:28427562
High-yield of biologically active recombinant human fibroblast growth factor-16 in E. coli and its mechanism of proliferation in NCL-H460 cells., PMID:28409700
In Vitro and in Vivo Analyses Reveal Profound Effects of Fibroblast Growth Factor 16 as a Metabolic Regulator., PMID:28011645
Expression of the Cardiac Maintenance and Survival Factor FGF-16 Gene Is Regulated by Csx/Nkx2.5 and Is an Early Target of Doxorubicin Cardiotoxicity., PMID:27929351
Roles of FGF Signals in Heart Development, Health, and Disease., PMID:27803896
Regulatory Differences in Natal Down Development between Altricial Zebra Finch and Precocial Chicken., PMID:27189543
Fgf3 and Fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear., PMID:26995070
GATA4 regulates Fgf16 to promote heart repair after injury., PMID:26893347
Expression of FGFs during early mouse tongue development., PMID:26748348
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors., PMID:26137434
Instability restricts signaling of multiple fibroblast growth factors., PMID:25854632
Genetic mechanisms leading to primary amenorrhea in balanced X-autosome translocations., PMID:25747126
Fgf16 is required for specification of GABAergic neurons and oligodendrocytes in the zebrafish forebrain., PMID:25357195
Heart-specific expression of FGF-16 and a potential role in postnatal cardioprotection., PMID:25106133
Identification of a novel familial FGF16 mutation in metacarpal 4-5 fusion., PMID:24878828
Further evidence for FGF16 truncating mutations as the cause of X-linked recessive fusion of metacarpals 4 / 5., PMID:24706454
Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation., PMID:24516404
FGF16 promotes invasive behavior of SKOV-3 ovarian cancer cells through activation of mitogen-activated protein kinase (MAPK) signaling pathway., PMID:24253043