Anti-Human Insulin Monoclonal Antibody (1A220)

Catalog No.

MHB94002

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Immunogen

Recombinant Human Insulin protein.

Target

Insulin, Insulin B chain, Insulin A chain, INS

Concentration

1mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01308

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

1A220

Rapid and Slow Progressors Toward β-Cell Depletion and Their Predictors in Type 1 Diabetes: Prospective Longitudinal Study in Japanese Type 1 Diabetes (TIDE-J)., PMID:40509916

Phenotypic Spectrum at Diagnosis of Age-Related Endotypes of Type 1 Diabetes Mellitus: A Cross-Sectional Study in China., PMID:40501403

Teprotumumab in the management of thyroid eye disease mechanistic insights and adverse reactions: a comprehensive review., PMID:40496563

Genetic variants and characterization of MODY in a single, large pediatric referral center., PMID:40486976

The Use of Biologics for Thyroid Eye Disease., PMID:40478400

Transient islet-antigen 2 positivity at diagnosis of diabetes during COVID-19 infection in an adolescent with a NEUROD1 variant: a case report., PMID:40474235

The evolution of the therapeutic concept 'GIP receptor antagonism'., PMID:40469445

A comparison of current methods to measure antibodies in type 1 diabetes., PMID:40460837

Dual Conjugation of Long- and Medium-Chain Fatty Acids to BimBH3 Peptide Yields Ultra Long-Acting Inhibitors of Intracellular PTPN1/2., PMID:40458949

Prevalence of Diabetes-related Autoantibodies Among Individuals with Type 2 Diabetes from Primary Care and Endocrinology Community Practice Settings., PMID:40456314

The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313

Preclinical Safety., PMID:40445826

Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice., PMID:40441535

Canakinumab for the treatment of postprandial hypoglycaemia: study protocol for a randomised, placebo-controlled, parallel-group, double-blind, multicentric, superiority trial-the CanpHy study., PMID:40425249

PIK3R1 mutations in individuals with insulin resistance or growth retardation: Case series and in silico functional analysis., PMID:40420664

[Prospects for treating Alzheimer's disease]., PMID:40420451

One-year metreleptin in Colombian sisters with congenital leptin deficiency., PMID:40415699

[TYPE 1 DIABETES MELLITUS AND MONOGENIC DIABETES - CAN THE TWO WALK TOGETHER?]., PMID:40413587

Comparative efficacy and safety of rituximab, tocilizumab, and teprotumumab in Graves' orbitopathy: a systematic review and meta-analysis., PMID:40404973

Clinical, genetic, and proteomic characteristics of type 2 diabetes complicated with exogenous insulin antibody syndrome: a case-control study., PMID:40404055

Evaluation of proinsulin(F25D) as a targeting ligand for insulin-binding B cells in autoimmune diabetes., PMID:40402465

Sintilimab-induced diabetes mellitus and thyroid dysfunction in patient with gastric adenocarcinoma: A case report and literature review., PMID:40388765

Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS., PMID:40385697

Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies., PMID:40383129

An analysis of the relationship of triglyceride glucose index with diffuse large B-cell lymphoma prognosis: a retrospective study., PMID:40357210

Teplizumab: a promising intervention for delaying type 1 diabetes progression., PMID:40357199

Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review., PMID:40355790

Lecanemab Treatment in a Specialty Memory Clinic., PMID:40354064

A candidate reference measurement procedure for quantification of human insulin in serum based on immunoaffinity extraction and isotope dilution-liquid chromatography-tandem mass spectrometry., PMID:40353876

Transient Anti-Glutamic Acid Decarboxylase (GAD) Antibody Positivity and Insulin Secretion Reduction After IVIg in Type 2 Diabetes Mellitus., PMID:40351955

Hepatic stellate cell-specific Kcnma1 deletion mitigates metabolic dysfunction-associated steatotic liver disease progression via upregulating Amphiregulin secretion., PMID:40348016

Genotype, Phenotype, and Clinical Characteristics of Maturity-onset Diabetes of the Young (MODY): Predominance of GCK-MODY., PMID:40338033

Colonic inflammation triggers β cell proliferation during obesity development via a liver-to-pancreas interorgan mechanism., PMID:40337860

Salmonella-Based Vaccine: A Promising Strategy for Type 1 Diabetes., PMID:40333284

Interferon Causes Endothelial Injury in Humans., PMID:40326264

Thyroid eye disease (Graves' orbitopathy): clinical presentation, epidemiology, pathogenesis, and management., PMID:40324443

Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms., PMID:40323219

Inhibition of DNA glycoxidation by mannitol and Pyridoxamine: Implications for DNA-antibody development in diabetes and diabetic retinopathy., PMID:40320156

Antibody reactivity in cerebrospinal fluid and serum against the insulin-insulin-like growth factor 2 (INS-IGF2) protein is associated with psychotic symptomatology in patients with schizophrenia or related psychosis., PMID:40319454

Thyroid-related orbitopathy: clinical overview, novel medical treatments and the role of orbital surgery., PMID:40317422

Insulin autoimmune syndrome in a patient with vitiligo: a case report and review of literature., PMID:40317087

The partial clinical remission phase of type 1 diabetes: early-onset dyslipidemia, long-term complications, and disease-modifying therapies., PMID:40309446

Prognostic value of the triglyceride-glucose index in advanced gastric cancer: A call for further exploration., PMID:40309236

Slowly Progressive Type 1 Diabetes following Steroid-Sensitive Relapsing Nephrotic Syndrome in Childhood: A Case Report., PMID:40297738

A cucurbit[7]uril-mediated crosslinking-amplified microchannel resistance immunoassay via magnetic interception for point of care testing of insulin., PMID:40294465

Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073

GLP- 1R status using validated monoclonal antibody in 689 cases of neuroendocrine neoplasm and its correlation with somatostatin receptor scintigraphy, insulin production, and histological grades., PMID:40281248

Analysis of multiple insulin actions in single muscle fibres from insulin resistant mice reveals selective defect in endogenous GLUT4 translocation., PMID:40272884

The Glucagon Receptor Is Expressed in the Frontal Cortex and Impaired Signaling Associates With Cognitive Decline., PMID:40271226

Diffusion dimensionality modeling of subcutaneous/intramuscular absorption of antibodies and long-acting injectables., PMID:40263185

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