Catalog No.
MHG80904
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Immunogen
Mammalian cells - derived recombinant Human WFDC2 / WAP5 (Met1-Phe124).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:2000-1:8000
Target
Epididymal secretory protein E4,Major epididymis-specific protein E4,HE4,WFDC2,WAP5,WAP four-disulfide core domain protein 2,Putative protease inhibitor WAP5,
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14508
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
1A083
Human epididymis secretory protein 4 in idiopathic inflammatory myopathy-associated interstitial lung disease., PMID:40095259
Cooperative amplification of Prussian blue as a signal indicator and functionalized metal-organic framework-based electrochemical biosensor for an ultrasensitive HE4 assay., PMID:38959719
Comprehensive analysis of the lncRNAs-related immune gene signatures and their correlation with immunotherapy in lung adenocarcinoma., PMID:37543671
Sensitive Detection of the Human Epididymis Protein-4 (HE4) Ovarian Cancer Biomarker through a Sandwich-Type Immunoassay Method with Laser-Induced Breakdown Spectroscopy., PMID:36762387
Metal exposure from additive manufacturing and its effect on the nasal lavage fluid proteome - a pilot study., PMID:34464420
HE4 Predicts Progressive Fibrosis and Cardiovascular Events in Patients With Dilated Cardiomyopathy., PMID:34320813
Substrate-Induced Growth of Micro/Nanostructured Zn(OH)F Arrays for Highly Sensitive Microfluidic Fluorescence Assays., PMID:34124881
An SPRi Biosensor for Determination of the Ovarian Cancer Marker HE4 in Human Plasma., PMID:34065481
Review of biomarker systems as an alternative for early diagnosis of ovarian carcinoma., PMID:33840014
Coupling metal-organic framework nanosphere and nanobody for boosted photoelectrochemical immunoassay of Human Epididymis Protein 4., PMID:32200889
Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer., PMID:31714597
The use of aggregation-induced emission probe doped silica nanoparticles for the immunoassay of human epididymis protein 4., PMID:31536063
Ovarian carcinomas express HE4 epitopes independently of each other., PMID:31226514
Sensitive amperometric immunosensor with improved electrocatalytic Au@Pd urchin-shaped nanostructures for human epididymis specific protein 4 antigen detection., PMID:31084737
C60 Mediated Ion Pair Interaction for Label-Free Electrochemical Immunosensing with Nanoporous Anodic Alumina Nanochannels., PMID:30908018
[Diagnostic and prognostic value of tumor markers, scores (clinical and biological) algorithms, in front of an ovarian mass suspected of an epithelial ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF and endorsed by INCa]., PMID:30733191
Ultrasensitive Electrochemical Immunoassay Based on Cargo Release from Nanosized PbS Colloidosomes., PMID:30624055
Label-free immunosensors based on a novel multi-amplification signal strategy of TiO2-NGO/Au@Pd hetero-nanostructures., PMID:30605806
Neutral Charged Immunosensor Platform for Protein-based Biomarker Analysis with Enhanced Sensitivity., PMID:30582808
Serum human epididymis protein 4 is a predictor for developing nephritis in patients with systemic lupus erythematosus: A prospective cohort study., PMID:29747124
Electrochemical quantum dots-based magneto-immunoassay for detection of HE4 protein on metal film-modified screen-printed carbon electrodes., PMID:29501129
Preparation and characterization of a high-affinity monoclonal antibody against human epididymis protein-4., PMID:28928083
WAP four-disulfide core domain protein 2 promotes metastasis of human ovarian cancer by regulation of metastasis-associated genes., PMID:28679402
Rapid quantitation of human epididymis protein 4 in human serum by amplified luminescent proximity homogeneous immunoassay (AlphaLISA)., PMID:27568283
HE4 is a novel tissue marker for therapy response and progestin resistance in medium- and low-risk endometrial hyperplasia., PMID:27537387
The Establishment of an HE4-CLIA Method and the Combined Analysis of HE4 and CA125 in Ovarian Cancer., PMID:26990679
WAP four-disulfide core domain protein 2 gene(WFDC2) is a target of estrogen in ovarian cancer cells., PMID:26928556
Detection of Human Epididymis Protein 4 (HE4) in Human Serum Samples Using a Specific Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assay (ELISA)., PMID:26666630
Serum HE4: An Independent Prognostic Factor in Non-Small Cell Lung Cancer., PMID:26030627
Microchip ELISA coupled with cell phone to detect ovarian cancer HE4 biomarker in urine., PMID:25626535
Overexpression of Lewis y antigen promotes human epididymis protein 4-mediated invasion and metastasis of ovarian cancer cells., PMID:24998328
HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation., PMID:24975515
MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress., PMID:24886523
Pattern of tissue expression of CA-125 and HE4 in primary epithelial ovarian tumours and correlation with serum CA-125 levels., PMID:24083699
Cancer antigen 125, human epididymis 4, kallikrein 6, osteopontin and soluble mesothelin-related peptide immunocomplexed with immunoglobulin M in epithelial ovarian cancer diagnosis., PMID:24013103
Electrochemical immunosensors in breast and ovarian cancer., PMID:23933123
Anti-HE4 antibodies in infertile women and women with ovarian cancer., PMID:23727327
Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis., PMID:23353556
[HE4 and CA125 in ovarian cancer]., PMID:23234010
Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas., PMID:23084584
Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance., PMID:22745553
Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification., PMID:22305445
[HE4--a new tumor marker for ovarian cancer]., PMID:22524132
Comprehensive analysis of HE4 expression in normal and malignant human tissues., PMID:16607372
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma., PMID:12839961
For research use only. Not for human or drug use.
