Catalog No.
PHJ12601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DOK3 (Met57-Phe179).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Docking protein 3,Downstream of tyrosine kinase 3,DOK3
Purification
Purified by antigen affinity column.
Accession
Q7L591
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates., PMID:36428765
Profiling the origin, dynamics, and function of traction force in B cell activation., PMID:30087179
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling., PMID:27813071
Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands., PMID:25053811
The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters., PMID:23223229
B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster., PMID:21703542
Dok-3 plays a nonredundant role in negative regulation of B-cell activation., PMID:17363732
Dok-1 and Dok-2 are negative regulators of T cell receptor signaling., PMID:17329234
Inhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3., PMID:14993273
For research use only. Not for human or drug use.
