Catalog No.
PHJ08601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IL27RA (Glu123-Pro343).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
IL-27R subunit alpha,IL-27RA,ZcytoR1,Interleukin-27 receptor subunit alpha,Cytokine receptor WSX-1,IL-27R-alpha,IL-27 receptor subunit alpha,CRL1,WSX1,TCCR,IL27RA,Type I T-cell cytokine receptor,Cytokine receptor-like 1
Purification
Purified by antigen affinity column.
Accession
Q6UWB1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia., PMID:38804310
Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma., PMID:36867577
IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis., PMID:35430461
B cell-derived IL-27 promotes control of persistent LCMV infection., PMID:35022243
A prospective study revealing the role of an immune-related eRNA, WAKMAR2, in breast cancer., PMID:34321580
IL-27Rα: A Novel Molecular Imaging Marker for Allograft Rejection., PMID:32075272
IL-27 Negatively Controls Antifungal Activity in a Model of Invasive Pulmonary Aspergillosis., PMID:31991091
Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production., PMID:30127058
Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection., PMID:29593047
IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells., PMID:29020964
Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3., PMID:25348624
Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia., PMID:24408967
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39., PMID:23995234
Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection., PMID:23993651
The composite cytokine p28/cytokine-like factor 1 sustains B cell proliferation and promotes plasma cell differentiation., PMID:23836062
The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction., PMID:23165310
Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice., PMID:22927332
TCCR/WSX-1 is a novel angiogenic factor in age-related macular degeneration., PMID:22312192
T cell-specific overexpression of interleukin-27 receptor α subunit (WSX-1) prevents spontaneous skin inflammation in MRL/lpr mice., PMID:21332454
The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses., PMID:21281790
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells., PMID:21098093
Amelioration of experimental allergic rhinitis with suppression of topical immune responses by lack of IL-27/WSX-1 signaling., PMID:19354069
Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses., PMID:19246719
IL-27 induces a Th1 immune response and susceptibility to experimental arthritis., PMID:18178832
Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)., PMID:18094002
Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)., PMID:16301622
Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice., PMID:16081811
Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection., PMID:15067040
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27., PMID:14764690
Development of Th1-type immune responses requires the type I cytokine receptor TCCR., PMID:11057672
For research use only. Not for human or drug use.
