Catalog No.
YMJ65301
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly27-Ser177
Predicted molecular weight
19.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9JI71
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity., PMID:40493099
Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling., PMID:40447618
The association of energy and macronutrient intake at dinner versus breakfast with the incidence of hyperuricemia in US and Chinese adults., PMID:40436700
DLL4/VEGF bispecific molecularly imprinted nanomissile for robust tumor therapy., PMID:40381524
The inhibition of endothelial DLL4-NOTCH1 signaling by 2'-hydroxyflavanone enhances anti-PD-1 therapy in melanoma., PMID:40172769
Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling., PMID:40105819
DeltaC and DeltaD ligands play different roles in the segmentation clock dynamics., PMID:40069165
Another tail of two sites: activation of the Notch ligand Delta by Mindbomb1., PMID:40050848
Monocyte-derived Langerhans cells express Delta-like 4 induced by peptidoglycan and interleukin-4 mediated suppression., PMID:40018044
Notch2/3-DLL4 interaction in urothelial cancer cell lines supports a tumorigenic role of Notch signaling pathways in bladder carcinoma., PMID:39951484
A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization., PMID:39932958
Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway., PMID:39932433
Coordinated neuron-glia regeneration through Notch signaling in planarians., PMID:39869602
Autism-Linked Mutations in α2δ-1 and α2δ-3 Reduce Protein Membrane Expression but Affect Neither Calcium Channels nor Trans-Synaptic Signaling., PMID:39770450
Diversity in Notch ligand-receptor signaling interactions., PMID:39751380
Targeted delivery of DAPT using dual antibody functionalized solid lipid nanoparticles for enhanced anti-tumour activity against triple negative breast cancer., PMID:39746584
Echinococcus multilocularis delta/notch signalling components are expressed in post-mitotic cells., PMID:39714630
Higher intake energy, protein, and polyunsaturated fatty acids at dinner versus breakfast increase the risk of hyperhomocysteinemia among adults in the USA., PMID:39680148
Correlation between pre-operative VE-cadherin and DLL4 and the maturation after primary arteriovenous fistula in uremic patients., PMID:39583102
Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity., PMID:39564985
Activating PPARβ/δ-Mediated Fatty Acid β-Oxidation Mitigates Mitochondrial Dysfunction Co-induced by Environmentally Relevant Levels of Molybdenum and Cadmium in Duck Kidneys., PMID:39546187
DLL4-targeted CAR-T therapy sensitizes neoadjuvant chemotherapy via eliminating cancer stem cells and reshaping immune microenvironment in HER2+ breast cancer., PMID:39542653
Adipose-derived stem cell exosomal miR-21-5p enhances angiogenesis in endothelial progenitor cells to promote bone repair via the NOTCH1/DLL4/VEGFA signaling pathway., PMID:39516839
Differential Effects of Four Canonical Notch-Activating Ligands on c-Kit+ Cardiac Progenitor Cells., PMID:39456964
CD90's role in vascularization and healing of rib fractures: insights from Dll4/notch regulation., PMID:39455438
Oscillatory DeltaC Expression in Neural Progenitors Primes the Prototype of Forebrain Development., PMID:39392541
Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis., PMID:39390606
Notch signaling mediated repressive effects of resveratrol in inducing caspasedependent apoptosis in MCF-7 breast cancer cells., PMID:39262258
Efficient generation of human NOTCH ligand-expressing haemogenic endothelial cells as infrastructure for in vitro haematopoiesis and lymphopoiesis., PMID:39227582
Central Actions of Leptin Induce an Atrophic Pattern and Improves Heart Function in Lean Normoleptinemic Rats via PPARβ/δ Activation., PMID:39199415
Circ_0006476 modulates macrophage apoptosis through the miR-3074-5p/DLL4 axis: implications for Notch signalling pathway regulation in cardiovascular disease., PMID:39167432
Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity., PMID:39131389
Modulating endothelial cell dynamics in fat grafting: the impact of DLL4 siRNA via adipose stem cell extracellular vesicles., PMID:39099421
The Prediction of DLL4 as a Prognostic Biomarker in Patients with Gastric Cancer Using Anti-DLL4 Nanobody., PMID:39046662
KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy., PMID:38973459
Effect of humanine on the Notch signaling pathway in myocardial infarction., PMID:38813496
Molecular Mechanisms and Therapeutic Potential of Gabapentin with a Focus on Topical Formulations to Treat Ocular Surface Diseases., PMID:38794193
BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension., PMID:38791441
Endothelial to mesenchymal Notch signaling regulates skeletal repair., PMID:38781018
Endothelial HIF2α suppresses retinal angiogenesis in neonatal mice by upregulating NOTCH signaling., PMID:38770916
PPA1 promotes adipogenesis by regulating the stability of C/EBPs., PMID:38762596
Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling., PMID:38759515
Seco-cyclic phorbol derivatives and their anti-HIV-1 activities., PMID:38658099
Delta like 4 regulates cerebrovascular development and endothelial integrity via DLL4-NOTCH-CLDN5 pathway and is vulnerable to neonatal hyperoxia., PMID:38632887
Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain., PMID:38574735
The Nucleocapsid Protein of SARS-CoV-2, Combined with ODN-39M, Is a Potential Component for an Intranasal Bivalent Vaccine with Broader Functionality., PMID:38543783
Hypoxic environment promotes angiogenesis and bone bridge formation by activating Notch/RBPJ signaling pathway in HUVECs., PMID:38537807
LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer., PMID:38462037
Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling., PMID:38346959
PPARβ/δ-ANGPTL4 axis mediates the promotion of mono-2-ethylhexyl phthalic acid on MYCN-amplified neuroblastoma development., PMID:38042186
For research use only. Not for human or drug use.
