Catalog No.
YMF06001
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met160-Asn246
Predicted molecular weight
37.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01721
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GAS-1, GAS1, Growth arrest-specific protein 1
Growth Arrest-specific 1 Inhibits Keap1/Nrf2 Signaling Transduction in the Activation of the Ferroptosis Program in Retinal Müller Cells., PMID:40152386
Coding and regulatory somatic profiling of triple-negative breast cancer in Sub-Saharan African patients., PMID:40133516
Adaptive laboratory evolution induces cell wall alterations for succinic acid tolerance in Saccharomyces cerevisiae., PMID:40015526
Arsenolipid-induced reproductive toxicity in Caenorhabditis elegans: Elucidating the mechanism through the HUS-1-CEP-1-EGL-1-CED-9-CED-4-CED-3 signaling pathway., PMID:39986564
Disturbances in cell wall biogenesis as a key factor in the replicative aging of budding yeast., PMID:39907841
Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis., PMID:39889823
Hedgehog-dependent and hedgehog-independent roles for growth arrest specific 1 in mammalian kidney morphogenesis., PMID:39629522
You Don't Always Get What You Want!, PMID:39254540
Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion., PMID:39251867
Cystathionine γ-Lyase Attenuates Vascular Smooth Muscle Cell Senescence via Foxm1-Gas1 Pathway to Mediate Arterial Stiffness., PMID:39226170
Hedgehog components are overexpressed in a series of liver cancer cases., PMID:39174588
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis., PMID:39026176
Tumor necrosis factor α deficiency promotes myogenesis and muscle regeneration., PMID:39021083
Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis., PMID:38848388
TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression., PMID:38816533
Exposure to 6-PPD quinone causes damage on mitochondrial complex I/II associated with lifespan reduction in Caenorhabditis elegans., PMID:38743975
2,4,6-trinitrotoluene causes mitochondrial toxicity in Caenorhabditis elegans by affecting electron transport., PMID:38555093
Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1., PMID:38472182
Histone H3K36me3 mediates the genomic instability of Benzo[a]pyrene in human bronchial epithelial cells., PMID:38367693
GPI-anchored Gas1 protein regulates cytosolic proteostasis in budding yeast., PMID:38289859
Hypersecretory production of glucose oxidase in Pichia pastoris through combinatorial engineering of protein properties, synthesis, and secretion., PMID:38037762
GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver Failure., PMID:37859699
Identification of potential common genetic modifiers of neurofibromas: a genome-wide association study in 1333 patients with neurofibromatosis type 1., PMID:37831592
Loss of ATOH1 in Pit Cell Drives Stemness and Progression of Gastric Adenocarcinoma by Activating AKT/mTOR Signaling through GAS1., PMID:37824217
Comprehensive in silico analysis of glycosylphosphatidylinositol- anchored protein (GPI-AP) related genes expression profiles in human normal and cancer tissues., PMID:37609818
The impact of the Hedgehog signal pathway on the tumor immune microenvironment of gastric adenocarcinoma by integrated analysis of scRNA-seq and RNA-seq datasets., PMID:37526746
Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development., PMID:37516749
Effects of tri-n-butyl phosphate (TnBP) on neurobehavior of Caenorhabditis elegans., PMID:37389749
GPI-anchored Gas1 protein regulates cytosolic proteostasis in yeast., PMID:37292646
Primary testicular lymphoma demonstrates overexpression of the Wilms tumor 1 gene and different mRNA and miRNA expression profiles compared to nodal diffuse large B-cell lymphoma., PMID:37291944
Identification and Characterization of Novel Candidate Effector Proteins from Magnaporthe oryzae., PMID:37233285
Characterization of the pattern of expression of Gas1 in the kidney during postnatal development in the rat., PMID:37093844
Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling., PMID:36971701
A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements., PMID:36650051
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis., PMID:36459481
GAS1RR, an immune-related enhancer RNA, is related to biochemical recurrence-free survival in prostate cancer., PMID:36408742
Reproductive toxicity and underlying mechanisms of fine particulate matter (PM2.5) on Caenorhabditis elegans in different seasons., PMID:36379073
Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort., PMID:36378845
Identification of a dysregulated CircRNA-associated gene signature for predicting prognosis, immune landscape, and drug candidates in bladder cancer., PMID:36300085
Expression of growth arrest specific 1 (Gas1) in the distal tubules and collecting ducts in normal kidney and in the early stages of diabetic nephropathy., PMID:36272046
CDON contributes to Hedgehog-dependent patterning and growth of the developing limb., PMID:36265686
Microbial Interaction between Lactiplantibacillus plantarum and Saccharomyces cerevisiae: Transcriptome Level Mechanism of Cell-Cell Antagonism., PMID:35980205
The Value of the Stemness Index in Ovarian Cancer Prognosis., PMID:35741755
Copper inhibits protein maturation in the secretory pathway by targeting the Sec61 translocon in Saccharomyces cerevisiae., PMID:35738397
Potential anti-Parkinsonian's effect of S-(+)-linalool from Cinnamomum osmophloeum ct. linalool leaves are associated with mitochondrial regulation via gas-1, nuo-1, and mev-1 in Caenorhabditis elegans., PMID:35665972
Pregnane X receptor (PXR) represses osteoblast differentiation through repression of the Hedgehog signaling pathway., PMID:35421365
Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex., PMID:35231446
Mutation of Signal Transducer and Activator of Transcription 5 (STAT5) Binding Sites Decreases Milk Allergen αS1-Casein Content in Goat Mammary Epithelial Cells., PMID:35159497
Crystallographic snapshots of a B12-dependent radical SAM methyltransferase., PMID:35110733
Evaluation of Native Entomopathogenic Fungi for the Control of Fall Armyworm (Spodoptera frugiperda) in Thailand: A Sustainable Way for Eco-Friendly Agriculture., PMID:34947055