Catalog No.
YMN36701
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Arg99-Val195
Predicted molecular weight
23.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P97463
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NRTN, Neurturin
Identification of immune-associated genes and single-cell sequencing analysis in diagnosing Behçet's disease., PMID:40481130
Sympathetic cholinergic nerve fibres promote BMSC differentiation into osteoblasts via NRTN secretion: a potential treatment for osteoporosis., PMID:40474233
BHLHE40 contributes to allergic asthma progression in mice through NRTN downregulation in macrophages., PMID:40467844
Modulation of Neurturin Expression by Lumbosacral Spinal Stenosis, Lifestyle Factors, and Glycemic Dysregulation., PMID:40426929
Proteomic Profiling of Inflammatory Protein Dysregulation in HLA-B27-Positive Ankylosing Spondylitis: Molecular Signatures and Potential Biomarkers., PMID:40305235
Utilizing Sertoli Cell Transplantation as a Therapeutic Technique for the Management of Neurodegenerative Diseases., PMID:40256588
Deciphering genetic causality between plasma BDNF and 91 circulating inflammatory proteins through bidirectional mendelian randomization., PMID:40133606
Optimization of recombinant neurturin expression in Escherichia coli using response surface methodology., PMID:40100421
Neurturin-induced activation of GFRA2-RET axis potentiates pancreatic cancer glycolysis via phosphorylated hexokinase 2., PMID:39988080
Neurturin gene IVSI-663 polymorphism but not RET variants is associated with increased risk for breast cancer., PMID:39671698
Gene Therapy for Parkinson's Disease Using Midbrain Developmental Genes to Regulate Dopaminergic Neuronal Maintenance., PMID:39596436
Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons., PMID:39537338
Viral and nonviral approaches., PMID:39341664
Association of MCP-4, NRTN, and PD-L1 with the risk of hepatic fibrosis: A Mendelian randomization study., PMID:39252214
Genetically Predicted Association of 91 Circulating Inflammatory Proteins with Multiple Sclerosis: A Mendelian Randomization Study., PMID:39199524
The causal relationship between 91 inflammatory cytokines and Gestational Diabetes Mmellitus: A bidirectional two-sample Mendelian randomization study., PMID:39181454
Neurturin GF Enhances the Acute Cytokine Response of Inflamed Skin., PMID:39122143
Spatiotemporal regulation of dental pulpal innervation in the rat., PMID:39056435
Circulating inflammatory factors and risk causality associated with type 2 diabetic nephropathy: A Mendelian randomization and bioinformatics study., PMID:38996161
Comparison of the efficiency of the Sec and Tat secretory pathways in the secretion of recombinant neurturin protein using de novo designed signal peptides., PMID:38511632
The effects of induced type I diabetes on developmental regulation of GDNF, NRTN, and NCAM proteins in the dentate gyrus of male rat offspring., PMID:38219812
Expression of Glial-Cell-Line-Derived Neurotrophic Factor Family Ligands in Human Intervertebral Discs., PMID:37958856
Choice of fusion proteins, expression host, and analytics solves difficult-to-produce protein challenges in discovery research., PMID:37802118
Single-neuron neurodegeneration as a degenerative model for Parkinson's disease., PMID:37721280
Sputum Neurturin Levels in Adult Asthmatic Subjects., PMID:37671183
Post-Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10 Years CERE120 Delivery., PMID:37544016
Multi-omics study of key genes, metabolites, and pathways of periodontitis., PMID:37285682
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway., PMID:37211171
Restorative cell and gene therapies for Parkinson's disease., PMID:36803812
Neurotrophic factor-based pharmacological approaches in neurological disorders., PMID:36453397
Molecular pathogenesis and treatment of cavernous nerve injury-induced erectile dysfunction: A narrative review., PMID:36277218
Identification and Validation of Prognostic Markers for Lung Squamous Cell Carcinoma Associated with Chronic Obstructive Pulmonary Disease., PMID:36035311
Glial-derived neurotrophic factor regulates the expression of TREK2 in rat primary sensory neurons leading to attenuation of axotomy-induced neuropathic pain., PMID:35907583
Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach., PMID:35741092
Corrigendum to "Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer" [Exp. Cell Res. 413 (2022) 113049]., PMID:35584556
The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung's disease., PMID:35434281
Neurotrophins as Therapeutic Agents for Parkinson's Disease; New Chances From Focused Ultrasound?, PMID:35401084
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise., PMID:35276096
Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer., PMID:35114191
Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism., PMID:34907395
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity., PMID:34592133
Frey's syndrome: A review of the physiology and possible role of neurotrophic factors., PMID:34195362
Glial-derived neurotrophic factor in human airway smooth muscle., PMID:34170009
Neurotrophic Factors in Parkinson's Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain., PMID:34149364
Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson's disease., PMID:34100424
GDNF Therapy: Can We Make It Work?, PMID:33935108
GDNF signaling in subjects with minimal motor deficits and Parkinson's disease., PMID:33684514
Role of Liver Growth Factor (LGF) in Parkinson's Disease: Molecular Insights and Therapeutic Opportunities., PMID:33608826
Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP+ in dissociated cultures from rat mesencephalon., PMID:33534843
Intravenous infusion of mesenchymal stem cells delays disease progression in the SOD1G93A transgenic amyotrophic lateral sclerosis rat model., PMID:33516815
For research use only. Not for human or drug use.
