Catalog No.
YHN35801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro53-Tyr167
Predicted molecular weight
15.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y2G5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
POFUT2, FUT13, Peptide-O-fucosyltransferase 2, GDP-fucose protein O-fucosyltransferase 2, KIAA0958, C21orf80, O-FucT-2
Protein O-Fucosyltransferases: Biological Functions and Molecular Mechanisms in Mammals., PMID:40286076
IL-1β stimulates ADAMTS9 expression and contributes to preterm prelabor rupture of membranes., PMID:40057799
Knockout of the fcsk gene in zebrafish causes neurodevelopmental defects., PMID:40049660
FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains., PMID:39775168
Protein O-Fucosyltransferase Is Required for the Efficient Invasion of Hepatocytes by Plasmodium berghei Sporozoites., PMID:38421807
Transcriptome research of human amniocytes identifies hub genes associated with developmental dysplasia in down syndrome., PMID:38095646
Circulating Biomarkers and Risk of Hypertension: A Two-Sample Mendelian Randomisation Study., PMID:38042639
Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma., PMID:36852302
O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules., PMID:36721988
The Essential Role of Water Molecules in the Reaction Mechanism of Protein O-Fucosyltransferase 2., PMID:36260536
O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond., PMID:35597280
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development., PMID:35167946
O-Fucosylation of ADAMTSL2 is required for secretion and is impacted by geleophysic dysplasia-causing mutations., PMID:32913123
Upregulation of Fucosyltransferase 3, 8 and protein O-Fucosyltransferase 1, 2 genes in esophageal cancer stem-like cells (CSLCs)., PMID:32157457
ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome., PMID:31600785
Analyzing the Effects of O-Fucosylation on Secretion of ADAMTS Proteins Using Cell-Based Assays., PMID:31463900
Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development., PMID:31334132
O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites., PMID:30538131
Protein O-fucosyltransferase 2-mediated O-glycosylation of the adhesin MIC2 is dispensable for Toxoplasma gondii tachyzoite infection., PMID:30514763
Fucosylation genes as circulating biomarkers for lung cancer., PMID:30101373
A perspective on structural and mechanistic aspects of protein O-fucosylation., PMID:30084393
Systematic Functional Characterization of Human 21st Chromosome Orthologs in Caenorhabditis elegans., PMID:29367452
Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts., PMID:28916755
O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking., PMID:28729422
Biological functions of fucose in mammals., PMID:28430973
Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia., PMID:27773385
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome., PMID:27687499
Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion., PMID:27297885
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2., PMID:26854667
O-Fucosylation of CCN1 is required for its secretion., PMID:26424659
Peters plus syndrome mutations disrupt a noncanonical ER quality-control mechanism., PMID:25544610
Novel roles for O-linked glycans in protein folding., PMID:25186198
LIF upregulates poFUT1 expression and promotes trophoblast cell migration and invasion at the fetal-maternal interface., PMID:25165882
6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin type-1 repeats by protein O-fucosyltransferases 1 and 2., PMID:23045360
Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O-fucosylation., PMID:22588082
Structural insights into the mechanism of protein O-fucosylation., PMID:21966509
O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation., PMID:20637190
O-fucosylation is required for ADAMTS13 secretion., PMID:17395589
O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily., PMID:17395588
Molecular cloning and characterization of a novel human beta1,3-glucosyltransferase, which is localized at the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain., PMID:16899492
Molecular evolution of protein O-fucosyltransferase genes and splice variants., PMID:16679357
Histology-based expression profiling yields novel prognostic markers in human glioblastoma., PMID:16254489
The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development., PMID:15233996
A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs., PMID:12966037