Catalog No.
YHN35701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe2-Glu118
Predicted molecular weight
26.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y224
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CLE, CLE7 homolog, hCLE, RTRAF, RNA transcription, translation and transport factor protein, C14orf166
ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis., PMID:38503217
An in silico prediction of interaction models of influenza A virus PA and human C14orf166 protein from yeast-two-hybrid screening data., PMID:37265372
Molecular architecture of the human tRNA ligase complex., PMID:34854379
Role of C14orf166 in viral infection and RNA metabolism and its relationship with cancer (Review)., PMID:33786620
hCLE/RTRAF-HSPC117-DDX1-FAM98B: A New Cap-Binding Complex That Activates mRNA Translation., PMID:30833903
Combined proteomic and miRNome analyses of mouse testis exposed to an endocrine disruptors chemicals mixture reveals altered toxicological pathways involved in male infertility., PMID:30698749
Overexpressed C14orf166 associates with disease progression and poor prognosis in non-small-cell lung cancer., PMID:30126850
CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling., PMID:28166202
FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression., PMID:28040436
Expression and clinical significance of C14orf166 in esophageal squamous cell carcinoma., PMID:28000881
C14orf166 is a high-risk biomarker for bladder cancer and promotes bladder cancer cell proliferation., PMID:26905879
C14orf166 overexpression correlates with tumor progression and poor prognosis of breast cancer., PMID:26883017
hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles., PMID:26864902
C14ORF166 overexpression is associated with pelvic lymph node metastasis and poor prognosis in uterine cervical cancer., PMID:26219895
Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC., PMID:25964093
hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex., PMID:24608264
Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication., PMID:21900157
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein., PMID:21823664
Proteomic profiling in pancreatic cancer with and without lymph node metastasis., PMID:19152423
hCLE/CGI-99, a human protein that interacts with the influenza virus polymerase, is a mRNA transcription modulator., PMID:16950395
A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors., PMID:15147888
PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators., PMID:11507205
For research use only. Not for human or drug use.
