Catalog No.
YHN35501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser212-Ser311
Predicted molecular weight
13.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9ULX3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NOB1P, NOB1, Phosphorylation regulatory protein HP-10, PSMD8BP1, RNA-binding protein NOB1, Protein ART-4, ART4
The proximity proteome of pre-40S pre-ribosomal particle components PNO1 and NOB1 using turboID proximity labeling technology., PMID:40157618
Pan-cancer exploration of PNO1: A prospective prognostic biomarker with ties to immune infiltration., PMID:39263087
Ribosome Biogenesis and Cancer: Insights into NOB1 and PNO1 Mechanisms., PMID:39143880
The kinase Rio1 and a ribosome collision-dependent decay pathway survey the integrity of 18S rRNA cleavage., PMID:39038273
Increased Expression and Prognostic Significance of BYSL in Melanoma., PMID:38980088
Prognostic value of NOB1 expression levels in various cancers: a systematic review and meta-analysis., PMID:38881528
In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation., PMID:38509156
Pien Tze Huang Inhibits Proliferation of Colorectal Cancer Cells through Suppressing PNO1 Expression and Activating p53/p21 Signaling Pathway., PMID:38216838
PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway., PMID:38071381
Partner of NOB1 homolog transcriptionally activated by E2F transcription factor 1 promotes the malignant progression and inhibits ferroptosis of pancreatic cancer., PMID:37929351
Domain definition and preliminary functional exploration of the endonuclease NOBP-1 in Strongyloides stercoralis., PMID:37924155
Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors., PMID:36996028
[Corrigendum] Gene silencing of NOB1 by lentivirus suppresses growth and migration of human osteosarcoma cells., PMID:36484386
miRNA-612 suppresses ovarian cancer cell tumorigenicity by downregulating NOB1., PMID:35836846
The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo., PMID:35500030
Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple‑negative breast cancer., PMID:35445733
Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu)., PMID:35294329
Expression and distribution of Nob1 in the developing rat cochleae., PMID:35288316
Sublethal heat treatment promotes breast cancer metastasis and its molecular mechanism revealed by quantitative proteomic analysis., PMID:35150481
Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion., PMID:35148993
Capillary Electrophoresis-Based Functional Genomics Screening to Discover Novel Archaeal DNA Modifying Enzymes., PMID:34788065
LncRNA FEZF1-AS1 aggravates cell proliferation and migration in glioblastoma., PMID:34530115
The final step of 40S ribosomal subunit maturation is controlled by a dual key lock., PMID:33908345
Knockdown of PNO1 inhibits esophageal cancer progression., PMID:33864661
Structural basis for the final steps of human 40S ribosome maturation., PMID:33208940
MicroRNA-363-3p downregulation in papillary thyroid cancer inhibits tumor progression by targeting NOB1., PMID:33077486
Aberrant expression of miRNA-192-5p contributes to N,N-dimethylformamide-induced hepatic apoptosis., PMID:32648274
MiR-363 suppresses cell migration, invasion, and epithelial-mesenchymal transition of osteosarcoma by binding to NOB1., PMID:32357945
MicroRNA-612 inhibits cervical cancer progression by targeting NOB1., PMID:31970934
Silencing NOB1 Can Affect Cell Proliferation and Apoptosis Via the C-Jun N-Terminal Kinase Pathway in Colorectal Cancer., PMID:31906747
A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool., PMID:31834877
Importance of PNO1 for growth and survival of urinary bladder carcinoma: Role in core-regulatory circuitry., PMID:31800162
Celecoxib Inhibits Hepatocellular Carcinoma Cell Growth and Migration by Targeting PNO1., PMID:31568401
MicroRNA-139-3p suppresses growth and metastasis of glioblastoma via inhibition of NIN1/RPNI2 binding protein 1 homolog., PMID:31173298
Long non-coding RNA ZFAS1 regulates NOB1 expression through interacting with miR-646 and promotes tumorigenesis in osteosarcoma., PMID:31081072
NOB1: A Potential Biomarker or Target in Cancer., PMID:30854959
Interactions and activities of factors involved in the late stages of human 18S rRNA maturation., PMID:30638116
MicroRNA‑744 suppresses cell proliferation and invasion of papillary thyroid cancer by directly targeting NOB1., PMID:30628685
[Eukaryotic translation elongation factor 1A1 positively regulates NOB1 expression to promote invasion and metastasis of hepatocellular carcinoma cells in vitro]., PMID:30377124
NOB1 Gene as a Potential Biomarker in Clinical Outcomes and Prognosis of Patients with Gastric Cancer., PMID:30274015
Observing and tracking single small ribosomal subunits in vivo., PMID:30194975
Domain definition and interaction mapping for the endonuclease complex hNob1/hPno1., PMID:30176151
Visualizing late states of human 40S ribosomal subunit maturation., PMID:29875412
miR‑145 inhibits human non‑small-cell lung cancer growth by dual-targeting RIOK2 and NOB1., PMID:29749434
Effects of NOB1 on the pathogenesis of osteosarcoma and its expression on the chemosensitivity to cisplatin., PMID:29467874
Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit., PMID:29459436
Low-level miR-646 in colorectal cancer inhibits cell proliferation and migration by targeting NOB1 expression., PMID:29391877
MicroRNA-363 inhibits ovarian cancer progression by inhibiting NOB1., PMID:29254193
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae., PMID:29155690
Long non-coding RNA SNHG1 regulates NOB1 expression by sponging miR-326 and promotes tumorigenesis in osteosarcoma., PMID:29115574
For research use only. Not for human or drug use.
