Catalog No.
YHN33201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly212
Predicted molecular weight
26.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H9A7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RecQ-mediated genome instability protein 1, RMI1, FAAP75, BLM-associated protein of 75 kDa, BLAP75, C9orf76
Potent Cyclic Peptide Inhibitors Disrupt the FANCM-RMI Interaction., PMID:40479515
Deciphering the human TopIIIα activity modulated by Rmi1 using magnetic tweezers., PMID:40266687
A CPC-shelterin-BTR axis regulates mitotic telomere deprotection., PMID:40097392
The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges., PMID:39870965
Transcriptional analysis reveals the suppression of RAD51 and disruption of the homologous recombination pathway during PEDV infection in IPEC-J2 cells., PMID:39731192
RMI1 is essential for maintaining rice genome stability at high temperature., PMID:39569466
Sleep-enhancing effect of Hongcheon-hop (Humulus lupulus L.) extract containing xanthohumol and humulone through GABAA receptor., PMID:39522843
Risk-prediction models in postmenopausal patients with symptoms of suspected ovarian cancer in the UK (ROCkeTS): a multicentre, prospective diagnostic accuracy study., PMID:39362250
Fluorescence polarization assay for screening FANCM-RMI inhibitors to target the alternative lengthening of telomeres., PMID:38886039
Nonhomologous tails direct heteroduplex rejection and mismatch correction during single-strand annealing in Saccharomyces cerevisiae., PMID:38315739
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution., PMID:38266639
RMI1 facilitates repair of ionizing radiation-induced DNA damage and maintenance of genomic stability., PMID:38007566
Structural characterization of human RPA70N association with DNA damage response proteins., PMID:37668474
The SUMO-NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure., PMID:37474739
TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX-deficient cells., PMID:37013192
KNO1-mediated autophagic degradation of the Bloom syndrome complex component RMI1 promotes homologous recombination., PMID:36970874
Identification of immune-related genes in diagnosing atherosclerosis with rheumatoid arthritis through bioinformatics analysis and machine learning., PMID:36969166
Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates., PMID:36942481
Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair., PMID:36793865
Comparisons of Effectiveness in Differentiating Benign from Malignant Ovarian Masses between Conventional and Modified Risk of Malignancy Index (RMI)., PMID:36613208
The MRN complex and topoisomerase IIIa-RMI1/2 synchronize DNA resection motor proteins., PMID:36529288
Multifaceted regulation of the sumoylation of the Sgs1 DNA helicase., PMID:35654140
The topoisomerase 3 zinc finger domain cooperates with the RMI1 scaffold to promote stable association of the BTR complex to recombination intermediates in the Caenorhabditis elegans germline., PMID:35639927
RecQ mediated genome instability 2 (RMI2): a potential prognostic and immunological biomarker for pan-cancers., PMID:35552266
Generation of double Holliday junction DNAs and their dissolution/resolution within a chromatin context., PMID:35452329
Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome., PMID:35218564
The CDK1-TOPBP1-PLK1 axis regulates the Bloom's syndrome helicase BLM to suppress crossover recombination in somatic cells., PMID:35119917
The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops., PMID:35115525
Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability., PMID:35115399
Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex., PMID:35102151
Regulation of interference-sensitive crossover distribution ensures crossover assurance in Arabidopsis., PMID:34795056
The DNA-dependent protease AtWSS1A suppresses persistent double strand break formation during replication., PMID:34761387
Germline mutations in a DNA repair pathway are associated with familial colorectal cancer., PMID:34549727
Genetic mechanisms of COVID-19 and its association with smoking and alcohol consumption., PMID:34308962
RMI2 is a prognostic biomarker and promotes tumor growth in hepatocellular carcinoma., PMID:34275027
Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex., PMID:34252074
Screening of cervical cancer-related hub genes based on comprehensive bioinformatics analysis., PMID:34151839
PrimPol-mediated repriming facilitates replication traverse of DNA interstrand crosslinks., PMID:34128550
Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications., PMID:34021944
A vertebrate adaptive radiation is assembled from an ancient and disjunct spatiotemporal landscape., PMID:33990463
Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites., PMID:33833229
DNA topoisomerase 3 is required for efficient germ cell quality control., PMID:33798260
Identification and external validation of a prognostic signature associated with DNA repair genes in gastric cancer., PMID:33785812
Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper-resection., PMID:33764556
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex., PMID:33678249
Different functional roles of RTR complex factors in DNA repair and meiosis in Arabidopsis and tomato., PMID:33619799
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks., PMID:33500419
A Structural Guide to the Bloom Syndrome Complex., PMID:33357470
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure., PMID:33202158
Variants in Homologous Recombination Genes EXO1 and RAD51 Related with Premature Ovarian Insufficiency., PMID:32772095
For research use only. Not for human or drug use.
