Catalog No.
YHN32701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly374-Asp611
Predicted molecular weight
29.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BY66
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Jumonji/ARID domain-containing protein 1D, [histone H3]-trimethyl-L-lysine(4) demethylase 5D, H-Y, JARID1D, HY, SMCY, KDM5D, Histone demethylase JARID1D, HYA, Lysine-specific demethylase 5D, KIAA0234, Histocompatibility Y antigen, Protein SmcY
Identification and functional analysis of novel biomarkers related to retinal neovascularization in proliferative diabetic retinopathy., PMID:40331545
Discovery of KDM5D as a novel biomarker for traumatic brain injury identified through bioinformatics analysis., PMID:40196131
KDM5C and KDM5D mutations have different consequences in clear cell renal cell carcinoma cells., PMID:39955388
KDM5D histone demethylase mediates p38α inactivation via its enzymatic activity to inhibit cancer progression., PMID:39636854
Transcriptome Analysis Reveals the Early Development in Subcutaneous Adipose Tissue of Laiwu Piglets., PMID:39457885
Comprehensive Analysis of Juvenile Nasopharyngeal Angiofibromas via Whole-Exome Sequencing., PMID:39297564
Molecular Hallmarks of Prostate-specific Membrane Antigen in Treatment-naïve Prostate Cancer., PMID:39294048
Novel Role of the ALPI Gene Associated with Constipation Caused by Complement Component 3 Deficiency., PMID:39273477
SGK1 contributes to ferroptosis in coronary heart disease through the NEDD4L/NF-κB pathway., PMID:39245317
Artificial neural network inference analysis identified novel genes and gene interactions associated with skeletal muscle aging., PMID:39210538
X and Y Differences in Melanoma Survival Between the Sexes., PMID:39180225
Comparing the roles of sex chromosome-encoded protein homologs in gene regulation., PMID:39048311
Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere Maintenance., PMID:39031441
Intestinal mRNA expression profiles associated with mucosal healing in ustekinumab-treated Crohn's disease patients: bioinformatics analysis and prospective cohort validation., PMID:38926732
Silencing DDX3 Attenuates Interleukin-1β-Induced Intervertebral Disc Degeneration Through Inhibiting Pyroptosis., PMID:38735906
Sex-Specific Expression of Histone Lysine Demethylases (KDMs) in Thyroid Cancer., PMID:38610938
Where Are the Formerly Y-linked Genes in the Ryukyu Spiny Rat that has Lost its Y Chromosome?, PMID:38478711
Early Onset Intrahepatic Cholangiocarcinoma: Clinical Characteristics, Oncological Outcomes, and Genomic/Transcriptomic Features., PMID:38347332
The epigenetic downregulation of LncGHRLOS mediated by RNA m6A methylase ZCCHC4 promotes colorectal cancer tumorigenesis., PMID:38326863
Bladder Cancer, Loss of Y Chromosome, and New Opportunities for Immunotherapy., PMID:38198042
Genomic insights and advanced machine learning: characterizing autism spectrum disorder biomarkers and genetic interactions., PMID:38153584
Copy number loss of KDM5D may be a predictive biomarker for ATR inhibitor treatment in male patients with pulmonary squamous cell carcinoma., PMID:37974379
A novel flow-cytometric based method to assess post-HSCT donor chimerism exploiting RNA hybridization., PMID:37935782
The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system., PMID:37657612
The Histone Demethylase KDM5D Drives Sex Differences in Colorectal Cancer., PMID:37387591
Histone demethylase KDM5D upregulation drives sex differences in colon cancer., PMID:37344599
PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter., PMID:36890610
The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation., PMID:36700827
Identification of Key Genes and Biological Pathways Related to Myocardial Infarction through Integrated Bioinformatics Analysis., PMID:36688193
The effect of miR-155-5p on M1 polarization of Kupffer cells and immune response during liver transplantation through regulating the expression of KDM5D., PMID:36641950
Integrated analyses reveal evolutionarily conserved and specific injury response genes in dorsal root ganglion., PMID:36323676
Increased MYBL2 expression in aggressive hormone-sensitive prostate cancer., PMID:36087093
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase., PMID:35545632
Expression, Prognostic Value, and Functional Mechanism of the KDM5 Family in Pancreatic Cancer., PMID:35493099
Integrative analyses of biomarkers and pathways for heart failure., PMID:35346191
Human Sex Matters: Y-Linked Lysine Demethylase 5D Drives Accelerated Male Craniofacial Osteogenic Differentiation., PMID:35269444
Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis., PMID:35132955
Systemic Profiling of KDM5 Subfamily Signature in Non-Small-Cell Lung Cancer., PMID:34737620
KDM5D inhibits the transcriptional activation of FKBP4 by suppressing the expression of E2F1 in colorectal cancer in males., PMID:34688635
The impact of sex on susceptibility to systemic lupus erythematosus and rheumatoid arthritis; a bioinformatics point of view., PMID:34662716
Assessment of immune status of laryngeal squamous cell carcinoma can predict prognosis and guide treatment., PMID:34643766
Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice., PMID:34545692
Increased Mars2 expression upon microRNA-4661-5p-mediated KDM5D downregulation is correlated with malignant degree of gastric cancer cells., PMID:34273914
Y disruption, autosomal hypomethylation and poor male lung cancer survival., PMID:34127738
The clinical significance of spondin 2 eccentric expression in peripheral blood mononuclear cells in bronchial asthma., PMID:33998076
Circulating Tumor Cell Genomic Evolution and Hormone Therapy Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer., PMID:33771885
Genomic and transcriptomic characterization of the human glioblastoma cell line AHOL1., PMID:33470396
Increased Expression of Y-Encoded Demethylases During Differentiation of Human Male Neural Stem Cells., PMID:33040644
[Integrated bioinformatics analysis of key genes in allergic rhinitis]., PMID:32842359
X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis., PMID:32732223
For research use only. Not for human or drug use.
