Catalog No.
YHN30501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys91-Arg197
Predicted molecular weight
25.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96EH3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitochondrial assembly of ribosomal large subunit protein 1, MALSU1, C7orf30
Mitochondria-Related Genome-Wide Mendelian Randomization Identifies Putatively Causal Genes for Neurodegenerative Diseases., PMID:39838927
Ortholog of autism candidate gene RBM27 regulates mitoribosomal assembly factor MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment., PMID:39480871
MALSU1-mediated regulation of mitochondrial function governs proliferation and doxorubicin resistance in triple-negative breast cancer cells., PMID:38896203
Autism candidate gene rbm-26 (RBM26/27) regulates MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment., PMID:37873356
Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival., PMID:37818824
Single-cell RNA sequencing identifies macrophage signatures correlated with clinical features and tumour microenvironment in meningiomas., PMID:37515398
Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival., PMID:36945631
Is RsfS a Hibernation Factor or a Ribosome Biogenesis Factor?, PMID:35790407
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit., PMID:35177605
A distinct assembly pathway of the human 39S late pre-mitoribosome., PMID:34315873
Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly., PMID:33283228
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes., PMID:33264405
Application of Cryo-EM for Visualization of Mitoribosomes., PMID:33230775
Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation., PMID:32652011
The Mitochondrial Acyl-carrier Protein Interaction Network Highlights Important Roles for LYRM Family Members in Complex I and Mitoribosome Assembly., PMID:31666358
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis., PMID:30085210
The conserved interaction of C7orf30 with MRPL14 promotes biogenesis of the mitochondrial large ribosomal subunit and mitochondrial translation., PMID:23171548
C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome., PMID:22238376
C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation., PMID:22238375