Catalog No.
YHF45201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn21-Lys206
Predicted molecular weight
23.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61587
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Rnd3, RHO8, RND3, Rho-related GTP-binding protein RhoE, Protein MemB, Rho family GTPase 3, Rho-related GTP-binding protein Rho8, ARHE, RHOE
Integrating machine learning and molecular docking to decipher the molecular network of aflatoxin b1-induced hepatocellular carcinoma., PMID:40392001
From Quiescence to Activation: The Reciprocal Regulation of Ras and Rho Signaling in Hepatic Stellate Cells., PMID:40358198
irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA., PMID:40140581
FLRT3 Overexpression Attenuates Ischemia-Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3., PMID:40047936
Diabetes Advances Cardiomyocyte Senescence Through Interfering Rnd3 Expression and Function., PMID:40025898
FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma., PMID:40020669
Rnd3 Ameliorates Diabetic Cardiac Microvascular Injury via Facilitating Trim40-Mediated Rock1 Ubiquitination., PMID:39792251
Rnd3 protects against doxorubicin-induced cardiotoxicity through inhibition of PANoptosis in a Rock1/Drp1/mitochondrial fission-dependent manner., PMID:39755713
Mechanistic insights into SIRT7 and EZH2 regulation of cisplatin resistance in bladder cancer cells., PMID:39719443
irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA., PMID:39386644
Identification of potential new T cell activation molecules: a Bioinformatic Approach., PMID:39333573
miR-135b-5p promotes gastric carcinogenesis by targeting CLIP4-mediated JAK2/STAT3 signal pathway., PMID:39121973
ALK -rearranged Mesenchymal Neoplasms With Prominent Foamy/Pseudolipogenic Cell Morphology : Expanding the Phenotypic Spectrum of ALK Fusion Neoplasms and Report of Novel Fusion Partners., PMID:38979776
RND3 modulates microglial polarization and alleviates neuroinflammation in Parkinson's disease by suppressing NLRP3 inflammasome activation., PMID:38744409
Mechanistic role of RND3-regulated IL33/ST2 signaling on cardiomyocyte senescence., PMID:38724005
Identification of New Markers of Angiogenic Sprouting Using Transcriptomics: New Role for RND3., PMID:38482696
RND3 Potentiates Proinflammatory Activation through NOTCH Signaling in Activated Macrophages., PMID:38343633
Malignant peritoneal mesotheliomas of rats induced by multiwalled carbon nanotubes and amosite asbestos: transcriptome and epigenetic profiles., PMID:38297314
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells., PMID:38224863
Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma., PMID:38218945
Rnd3 suppresses endothelial cell pyroptosis in atherosclerosis through regulation of ubiquitination of TRAF6., PMID:37743632
[Keloid nomogram prediction model based on weighted gene co-expression network analysis and machine learning]., PMID:37666763
Identification of fibroblast-related genes based on single-cell and machine learning to predict the prognosis and endocrine metabolism of pancreatic cancer., PMID:37588985
LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles., PMID:37469132
Exploration and validation of the hub genes involved in hypoxia-induced endothelial-mesenchymal transition of systemic sclerosis., PMID:37246768
A CRISPR interference strategy for gene expression silencing in multiple myeloma cell lines., PMID:37143063
Potential Anti-Candida albicans Mechanism of Trichoderma Acid from Trichoderma spirale., PMID:36982520
Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants., PMID:36834726
Loss of RhoE Function in Dermatofibroma Promotes Disorganized Dermal Fibroblast Extracellular Matrix and Increased Integrin Activation., PMID:36774976
A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing., PMID:36543131
Rnd3 Is a Crucial Mediator of the Invasive Phenotype of Glioblastoma Cells Downstream of Receptor Tyrosine Kinase Signalling., PMID:36496976
Fibroblast-specific activation of Rnd3 protects against cardiac remodeling in diabetic cardiomyopathy via suppression of Notch and TGF-β signaling., PMID:36438502
Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei., PMID:36235118
Microhydration of the metastable N-protomer of 4-aminobenzoic acid by condensation at 80 K: H/D exchange without conversion to the more stable O-protomer., PMID:36209005
Elevated expression of LIF predicts a poor prognosis and promotes cell migration and invasion of clear cell renal cell carcinoma., PMID:35992780
RND3 Transcriptionally Regulated by FOXM1 Inhibits the Migration and Inflammation of Synovial Fibroblasts in Rheumatoid Arthritis Through the Rho/ROCK Pathway., PMID:35699481
An investigation of mechanisms underlying mouse blastocyst hatching: a ribonucleic acid sequencing study., PMID:35559994
Silencing of RND3/RHOE inhibits the growth of human hepatocellular carcinoma and is associated with reversible senescence., PMID:35256752
The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding., PMID:35164151
HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network., PMID:34936021
Homozygous N-terminal missense variant in PLEKHG5 associated with intermediate CMT: A case report., PMID:34897098
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling., PMID:34883403
Identification and Analysis of Potential Autophagy-Related Biomarkers in Endometriosis by WGCNA., PMID:34790699
HOXD9 transcriptionally induced UXT facilitate breast cancer progression via epigenetic modification of RND3., PMID:34767964
Rnd3 is necessary for the correct oligodendrocyte differentiation and myelination in the central nervous system., PMID:34724108
Effect of RhoE expression on the migration and invasion of tongue squamous cell carcinoma., PMID:34636197
Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients., PMID:34433909
Serum levels of cytoskeleton remodeling proteins and their mRNA expression in tumor tissue of metastatic laryngeal and hypopharyngeal cancers., PMID:34231097
Different phosphorylation and farnesylation patterns tune Rnd3-14-3-3 interaction in distinct mechanisms., PMID:34163708
Maternal RND3/RhoE deficiency impairs placental mitochondrial function in preeclampsia by modulating the PPARγ-UCP2 cascade., PMID:34046947
For research use only. Not for human or drug use.
