Catalog No.
YHF37601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe192
Predicted molecular weight
23.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60763
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RAC3, Ras-related C3 botulinum toxin substrate 3, p21-Rac3
Intercepting the Downstream of the Estrogen Receptor Signaling Pathway: Discovery of a Potent and Efficient SRC-3 PROTAC Degrader for Overcoming Endocrine Resistance Breast Cancer., PMID:40434408
RHOA-associated disorder can be non-mosaic., PMID:40414526
Structural proteomics defines a sequential priming mechanism for the progesterone receptor., PMID:40355435
NCOA3 impairs the efficacy of anti-PD-L1 therapy via HSP90α/EZH2/CXCL9 axis in colon cancer., PMID:40215778
Hepatocyte TM4SF5-mediated cytosolic NCOA3 stabilization and macropinocytosis support albumin uptake and bioenergetics for hepatocellular carcinoma progression., PMID:40186033
PFKFB4 promotes endometrial cancer by regulating glycolysis through SRC‑3 phosphorylation., PMID:40116122
A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation., PMID:40015633
Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer., PMID:39921753
The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms., PMID:39682779
Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma., PMID:39659999
Characterization of novel small molecule inhibitors of estrogen receptor-activation function 2 (ER-AF2)., PMID:39593108
Radiomultiomics: quantitative CT clusters of severe asthma associated with multiomics., PMID:39401856
KLF1 Activates RAC3 to Mediate Fatty Acid Synthesis and Enhance Cisplatin Resistance in Bladder Cancer Cells., PMID:39376007
Characterization of serum proteomic and inflammatory profiling at early stage of iron deficiency in weaned piglets., PMID:39296492
SETD8 inhibits apoptosis and ferroptosis of Ewing's sarcoma through YBX1/RAC3 axis., PMID:38987564
Evaluation of the diagnostic utility of NCOA3, Maspin and VHL protein expression in pancreatic ductal adenocarcinoma: An immunohistochemical study., PMID:38901088
Unveiling the role of RAC3 in the growth and invasion of cisplatin-resistant bladder cancer cells., PMID:38847477
Novel insights into immune-related genes associated with type 2 diabetes mellitus-related cognitive impairment., PMID:38680704
Deciphering the prognostic features of bladder cancer through gemcitabine resistance and immune-related gene analysis and identifying potential small molecular drug PIK-75., PMID:38570787
Inhibition of RAC attenuates Adriamycin-induced podocyte injury., PMID:38552554
Deficiency of Nuclear Receptor Coactivator 3 Aggravates Diabetic Kidney Disease by Impairing Podocyte Autophagy., PMID:38483947
Identification and verification of anoikis-related gene markers to predict the prognosis of patients with bladder cancer and assist in the diagnosis and treatment of bladder cancer., PMID:38482431
Pediatric NCOA3-rearranged low-grade fibroblastic tumor with nuclear beta-catenin immunoreactivity., PMID:38340030
Integration of multi-omics and clinical treatment data reveals bladder cancer therapeutic vulnerability gene combinations and prognostic risks., PMID:38299148
Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features., PMID:38226966
Deciphering the significance of anoikis in bladder cancer and systematic analysis of S100A7 as a potential therapeutic target., PMID:38217031
An unusual presentation of de novo RAC3 variation in prenatal diagnosis., PMID:38214746
Pulsatilla saponin D regulates ras-related C3 botulinum toxin substrate 3 (RAC3) to overcome resistance to paclitaxel in lung adenocarcinoma cells., PMID:38200409
The genes significantly associated with an improved prognosis and long-term survival of glioblastoma., PMID:38019838
Expression Analysis of the Small GTP-Binding Protein Rac in Pterygium., PMID:38014881
A case of spindle cell rhabdomyosarcoma with a ZFP64::NCOA3 fusion., PMID:37905771
Rac2 mediate foam cell formation and associated immune responses in THP-1 to promote the process of atherosclerotic plaques., PMID:37837955
Early diagnosis and prognostic potential of RAC3 in bladder tumor., PMID:37728806
AIB1/SRC-3/NCOA3 function in estrogen receptor alpha positive breast cancer., PMID:37711895
Identification of hub anoikis-associated genes and risk signature in cutaneous melanoma., PMID:37401304
Krüppel-like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex., PMID:37401095
Integrated analysis identifies RAC3 as an immune-related prognostic biomarker associated with chemotherapy sensitivity in endometrial cancer., PMID:37386813
Establishment of a prognostic model to predict chemotherapy response and identification of RAC3 as a chemotherapeutic target in bladder cancer., PMID:37310098
Dispensable role of Rac1 and Rac3 after cochlear hair cell specification., PMID:37204479
Clinical profiling of MRD48 and functional characterization of two novel pathogenic RAC1 variants., PMID:37059841
Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m6A modification., PMID:37056933
NCoA3 upregulation in breast cancer‑associated adipocytes elicits an inflammatory profile., PMID:37026525
Depleting DDX1 sensitizes non-small cell lung cancer cells to chemotherapy by attenuating cancer stem cell traits., PMID:36934972
Clinicopathologic and genetic characterization of angiofibroma of soft tissue: a study of 12 cases including two cases with AHRR::NCOA3 gene fusion., PMID:36860189
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons., PMID:36744839
Protective role of circRNA CCND1 in ulcerative colitis via miR-142-5p/NCOA3 axis., PMID:36658474
Rac is required for the survival of cortical neurons., PMID:36586552
Translational Results of Zo-NAnTax: A Phase II Trial of Neoadjuvant Zoledronic Acid in HER2-Positive Breast Cancer., PMID:36555156
A novel focal adhesion-related risk model predicts prognosis of bladder cancer -- a bioinformatic study based on TCGA and GEO database., PMID:36357874
Zearalenone damages the male reproductive system of rats by destroying testicular focal adhesion., PMID:36288102
For research use only. Not for human or drug use.
