Catalog No.
YHD92301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys37-Ala152
Predicted molecular weight
16.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30988
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CT-R, CALCR, Calcitonin receptor
CALCR interaction with ANTXR1 drives gastric tumor growth and metastasis via AKT signaling pathway., PMID:40195530
A comprehensive spatio-cellular map of the human hypothalamus., PMID:39910307
In vivo recording from calcitonin receptor-expressing neurons in the medial preoptic area during affiliative social behaviors., PMID:39894414
A Cross-Species Atlas of the Dorsal Vagal Complex Reveals Neural Mediators of Cagrilintide's Effects on Energy Balance., PMID:39868309
TNBS colitis induces architectural changes and alpha-synuclein overexpression in mouse distal colon: A morphological study., PMID:39656240
A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells., PMID:39571704
Circadian Clock and Body Temperature., PMID:39289281
CALCR exacerbates renal cell carcinoma progression via stabilizing CD44., PMID:38985127
Nesting behavior is associated with body weight and grip strength loss in mice suffering from experimental arthritis., PMID:38155203
Cotadutide (GLP-1/Glucagon dual receptor agonist) modulates hypothalamic orexigenic and anorexigenic neuropeptides in obese mice., PMID:38147963
Distinct roles of amylin and oxytocin signaling in intrafamilial social behaviors at the medial preoptic area of common marmosets., PMID:38052969
Surface proteins of Propionibacterium freudenreichii MJ2 inhibit RANKL-induced osteoclast differentiation by lipocalin-2 upregulation and lipocalin-2-mediated NFATc1 inhibition., PMID:37730858
Geranylgeraniol Application in Human Osteoblasts and Osteoclasts for Reversal of the Effect of Bisphosphonates., PMID:37374134
Calcitonin receptor signaling in nucleus accumbens D1R- and D2R-expressing medium spiny neurons bidirectionally alters opioid taking in male rats., PMID:37355732
Molecular and Neural Mechanisms of Temperature Preference Rhythm in Drosophila melanogaster., PMID:37222551
Behavioral and histochemical characterization of sexually dimorphic responses to acute social isolation and reunion in mice., PMID:37030575
Polymorphisms in Genes Encoding VDR, CALCR and Antioxidant Enzymes as Predictors of Bone Tissue Condition in Young, Healthy Men., PMID:36834780
Role of Calcr expressing neurons in the medial amygdala in social contact among females., PMID:36658598
Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse model., PMID:36624436
Lysophosphatidylcholine (17:0) Improves HFD-Induced Hyperglycemia & Insulin Resistance: A Mechanistic Mice Model Study., PMID:36411788
Leukotriene B4 Loaded in Microspheres Inhibits Osteoclast Differentiation and Activation., PMID:36287497
Trimethylamine-N-Oxide Promotes Osteoclast Differentiation and Bone Loss via Activating ROS-Dependent NF-κB Signaling Pathway., PMID:36235607
Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions., PMID:36088585
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis., PMID:35536884
[Molecular genetic predictors of the development of urolithiasis]., PMID:35485826
Amylin-Calcitonin receptor signaling in the medial preoptic area mediates affiliative social behaviors in female mice., PMID:35136064
Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load., PMID:34856120
NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity., PMID:34462445
CALCR knockdown inhibits the development and progression of non-small-cell lung cancer., PMID:34417812
New loci and neuronal pathways for resilience to heat stress in cattle., PMID:34404823
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity., PMID:34210852
Inhibition of miR-29 Activity in the Myeloid Lineage Increases Response to Calcitonin and Trabecular Bone Volume in Mice., PMID:34192317
The Fungal Metabolite (+)-Terrein Abrogates Ovariectomy-Induced Bone Loss and Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastogenesis by Suppressing Protein Kinase-C α/βII Phosphorylation., PMID:34168561
Calcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care., PMID:34077719
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing., PMID:33962048
A genetic map of the mouse dorsal vagal complex and its role in obesity., PMID:33767443
The calcitonin receptor regulates osteocyte lacunae acidity during lactation in mice., PMID:33638943
Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma., PMID:33425026
Dlk1 regulates quiescence in calcitonin receptor-mutant muscle stem cells., PMID:33295098
Identification of the Significant Genes Regulated by Estrogen Receptor in Estrogen Receptor-Positive Breast Cancer and Their Expression Pattern Changes When Tamoxifen or Fulvestrant Resistance Occurs., PMID:33133141
Mechanism of miRNA-based Aconitum leucostomum Worosch. Monomer inhibition of bone marrow-derived dendritic cell maturation., PMID:32871480
Facilitatory and inhibitory role of central amylin administration in the regulation of the gonadotropin-releasing hormone pulse generator activity in goats., PMID:32771877
Amylin brain circuitry., PMID:32634450
The calcitonin-like system is an ancient regulatory system of biomineralization., PMID:32371888
Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding., PMID:31955990
The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells., PMID:31747590
Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced osteoclastogenesis., PMID:31675485
Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases., PMID:31639434
Identification of hub genes correlated with the pathogenesis and prognosis of gastric cancer via bioinformatics methods., PMID:31638362
Association between calcitonin receptor gene polymorphisms and calcium stone urolithiasis: A meta-analysis., PMID:31626518
For research use only. Not for human or drug use.
