Catalog No.
YHD39001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp20-Thr193
Predicted molecular weight
22.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20336
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-3A, RAB3A
Harnessing integrated bioinformatics to identify new diagnostic and therapeutic strategies for heart failure., PMID:40398828
Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism., PMID:40166812
The Rab3 GTPase cycle modulates cardiomyocyte exocytosis and atrial natriuretic peptide release., PMID:40119520
Rab3gap1 palmitoylation cycling modulates cardiomyocyte exocytosis and atrial natriuretic peptide release., PMID:39953729
UNC-10/SYD-2 links kinesin-3 to RAB-3-containing vesicles in the absence of the motor's PH domain., PMID:39662532
Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction., PMID:39412498
Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A., PMID:39071374
Serotonin Influences Insulin Secretion in Rat Insulinoma INS-1E Cells., PMID:38999937
Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice., PMID:38969501
A Transdermal Prion-Bionics Supermolecule as a RAB3A Antagonist for Enhancing Facial Youthfulness., PMID:38888508
Effects of bound nucleotides on the secondary structure, thermal stability, and phosphorylation of Rab3A., PMID:38824807
of Potential Noncoding RNAs Related to Spinal Cord Injury Based on Competing Endogenous RNAs., PMID:38809369
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors., PMID:38512027
Purification of time-resolved insulin granules reveals proteomic and lipidomic changes during granule aging., PMID:38421874
Rab3a attenuates spinal cord injury by mediating vesicle release., PMID:38253132
ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals., PMID:37881948
Developmental coordination disorder: What can we learn from RI mice using motor learning tasks and QTL analysis., PMID:37553802
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors., PMID:37546777
Decreased DHA-containing phospholipids in the neocortex of dementia with Lewy bodies are associated with soluble Aβ42 , phosphorylated α-synuclein, and synaptopathology., PMID:37463072
α-Synuclein is required for sperm exocytosis at a post-fusion stage., PMID:37287458
PIMT Controls Insulin Synthesis and Secretion through PDX1., PMID:37175791
Identification and Validation of Synapse-related Hub Genes after Spinal Cord Injury by Bioinformatics Analysis., PMID:37170986
cAMP-EPAC-PKCε-RIM1α signaling regulates presynaptic long-term potentiation and motor learning., PMID:37159499
Prediction of male fertility using Ras-related proteins., PMID:36812003
Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction., PMID:36590920
Rab3A interacts with spastin to regulate neurite outgrowth in hippocampal neurons., PMID:36587525
The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing., PMID:36467401
Identification of the common neurobiological process disturbed in genetic and non-genetic models for autism spectrum disorders., PMID:36371739
Localization Patterns of RAB3C Are Associated with Murine and Human Sperm Formation., PMID:36295569
Association of variants in the KIF1A gene with amyotrophic lateral sclerosis., PMID:36284339
Identification of a Signature for Predicting Prognosis and Immunotherapy Response in Patients with Glioma., PMID:36072978
Molecular and functional interactions of alpha-synuclein with Rab3a., PMID:35809645
Feline Adipose Derived Multipotent Stromal Cell Transdifferentiation Into Functional Insulin Producing Cell Clusters., PMID:35769100
Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina., PMID:35477223
Ras-related proteins (Rab) play significant roles in sperm motility and capacitation status., PMID:35180576
Neurodegeneration and astrogliosis in the entorhinal cortex in Alzheimer's disease: Stereological layer-specific assessment and proteomic analysis., PMID:35142030
Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction., PMID:35069169
MAFA and MAFB regulate exocytosis-related genes in human β-cells., PMID:34978761
MicroRNA‑126 protects SH‑SY5Y cells from ischemia/reperfusion injury‑induced apoptosis by inhibiting RAB3IP., PMID:34935056
Inhibition of Histamine Release from RBL-2H3 Cells by Zoledronate Did Not Affect Rab27a/Doc2a Interaction., PMID:34853276
TET3-mediated accumulation of DNA hydroxymethylation contributes to the activity-dependent gene expression of Rab3a in post-mitotic neurons., PMID:34645086
Proteomic Analysis Unveils Expressional Changes in Cytoskeleton- and Synaptic Plasticity-Associated Proteins in Rat Brain Six Months after Withdrawal from Morphine., PMID:34357055
Small Rab GTPases in Intracellular Vesicle Trafficking: The Case of Rab3A/Raphillin-3A Complex in the Kidney., PMID:34299299
Rab3a, a small GTP-binding protein, is required for the stabilization of the murine leukaemia virus Gag protein., PMID:34180342
Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish., PMID:34172817
The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells., PMID:34172739
Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB., PMID:34100549
Rab3 proteins and cancer: Exit strategies., PMID:33982832
Coordinated bi-directional trafficking of synaptic vesicle and active zone proteins in peripheral nerves., PMID:33933994
Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function., PMID:33542309
For research use only. Not for human or drug use.
