Catalog No.
YHD07701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly302-Glu441
Predicted molecular weight
18.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14921
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p54, EWSR2, ETS1, Protein C-ets-1
Hsa_circ_0049271 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance by Enhancing Cellular Senescence via miR-455-5p/ETS1., PMID:40503776
Dissecting the endothelial cell landscape in meningioma: single-cell insights into PLVAP+ subpopulations and their role in tumor angiogenesis., PMID:40496867
H3K18 lactylation-mediated Ythdf2 activation restrains mouse female germline stem cell proliferation via promoting Ets1 mRNA degradation., PMID:40426273
E26 transformation-specific-1 controls asthma development by regulating the CD4+ Th2/Th17 immune response involved transcription factors in active genomic transcriptional regions., PMID:40372772
Transcriptional regulation of ETV5 by mitogen-activated protein kinase via ETS-1 in human pancreatic cancer cells., PMID:40204967
A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency., PMID:40198713
ETS1 modulates ferroptosis to affect the process of myocardial ischemia-reperfusion injury via PIM3., PMID:40189183
ETS-1 in tumor immunology: implications for novel anti-cancer strategies., PMID:40181983
Exosomal miR-499a-5p from human umbilical cord mesenchymal stem cells attenuates liver fibrosis via targeting ETS1/GPX4-mediated ferroptosis in hepatic stellate cells., PMID:40108627
Unraveling the Dual Role of circ-CBLB and ETS-1 in Rheumatoid Arthritis: Biomarkers and Therapeutic Targets., PMID:40095292
Sequences within and upstream of the mouse Ets1 gene drive high level expression in B cells, but are not sufficient for consistent expression in T cells., PMID:40053568
ETS1 Protein Expression May Be Altered by the Complementarity of ETS1 mRNA Sequences with miR-203a-3p and miR-204-3p in Papillary Thyroid Carcinoma., PMID:39941022
ARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression., PMID:39843653
Cellular Senescence Genes as Cutting-Edge Signatures for Abdominal Aortic Aneurysm Diagnosis: Potential for Innovative Therapeutic Interventions., PMID:39823264
LHPP-P38 MAPK/ERK-ETS1 Axis Negative Feedback Signaling Restrains Progression in Breast Cancer., PMID:39789996
PARP-1 Inhibition Increases Oxidative Stress in Ets-1-Expressing MDA-MB-231 Breast Cancer Cells., PMID:39778077
MicroRNA-mediated Ets1 repression in retinal endothelial cells: A novel anti-angiogenic mechanism in nonproliferative diabetic retinopathy., PMID:39777974
ETS1 promotes cisplatin resistance of NSCLC cells by promoting GRP78 transcription., PMID:39521757
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma., PMID:39448867
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis., PMID:39383730
Caspase-1-dependent spatiality in triple-negative breast cancer and response to immunotherapy., PMID:39353903
LINC00887 promotes GCN5-dependent H3K27cr level and CRC metastasis via recruitment of YEATS2 and enhancing ETS1 expression., PMID:39349460
ETS1 deficiency in macrophages suppresses colorectal cancer progression by reducing the F4/80+TIM4+ macrophage population., PMID:39162797
ETS1 drives EGF-induced glycolytic shift and metastasis of epithelial ovarian cancer cells., PMID:39159682
Circ-PITX1 promotes non-small-cell lung cancer progression through regulating ETS1 expression via miR-615-5p., PMID:39138880
HDAC8 Enhances the Function of HIF-2α by Deacetylating ETS1 to Decrease the Sensitivity of TKIs in ccRCC., PMID:39073752
ETS1 Function in Leukemia and Lymphoma., PMID:39017852
ETS1 and RBPJ transcriptionally regulate METTL14 to suppress TGF-β1-induced epithelial-mesenchymal transition in human bronchial epithelial cells., PMID:39002703
ETS1-mediated Regulation of SOAT1 Enhances the Malignant Phenotype of Oral Squamous Cell Carcinoma and Induces Tumor-associated Macrophages M2-like Polarization., PMID:38993570
METTL3 promotes immature dental pulp stem cells-induced angiogenesis by regulating ETS1 mRNA stability in an m6A-HuR-dependent manner., PMID:38969870
miR-200c-3p regulates α4 integrin-mediated T cell adhesion and migration., PMID:38936759
Novel markers of MCL1 inhibitor sensitivity in triple-negative breast cancer cells., PMID:38762181
Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling., PMID:38759515
HMGA1 sensitizes esophageal squamous cell carcinoma to mTOR inhibitors through the ETS1-FKBP12 axis., PMID:38725843
ETS1, a Target Gene of the EWSR1::FLI1 Fusion Oncoprotein, Regulates the Expression of the Focal Adhesion Protein TENSIN3., PMID:38588446
M2 macrophages independently promote beige adipogenesis via blocking adipocyte Ets1., PMID:38388532
IGF2BP2-m6A-circMMP9 axis recruits ETS1 to promote TRIM59 transcription in laryngeal squamous cell carcinoma., PMID:38321126
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma., PMID:38299401
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression., PMID:38286256
Downregulation of circular RNA ETS1 promotes SLE activity and inhibits Treg cell differentiation through miR-1205/FoxP3 molecular axis., PMID:38244519
Allele-specific effect of various dietary fatty acids and ETS1 transcription factor on SCD1 expression., PMID:38167845
LncRNA USP2-AS1 facilitates the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting KDM3A/ETS1/USP2 to activate the Wnt/β-catenin signaling pathway., PMID:38131611
Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer., PMID:37968405
Hepatitis B doubly spliced protein (HBDSP) promotes hepatocellular carcinoma cell apoptosis via ETS1/GATA2/YY1-mediated p53 transcription., PMID:37929990
Downregulation of circETS1 disrupts Th17/Treg homeostasis by inhibiting FOXP3 transcription: A new potential biomarker in systemic lupus erythematosus., PMID:37852297
LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter., PMID:37789393
Mesenchymal Stem Cell-Derived Exosomes Mitigate Acute Murine Liver Injury via Ets-1 and Heme Oxygenase-1 Up-regulation., PMID:37723631
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?, PMID:37698712
Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus., PMID:37691956
SLC9A2, suppressing by the transcription suppressor ETS1, restrains growth and invasion of osteosarcoma via inhibition of aerobic glycolysis., PMID:37688782
For research use only. Not for human or drug use.
