Catalog No.
YHC29601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg215-Ser266
Predicted molecular weight
34.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08034
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GAP junction 28 kDa liver protein, Cx32, Connexin-32, Gap junction beta-1 protein, CX32, GJB1
Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker., PMID:40295550
Therapeutic sphingosine-1-phosphate receptor modulation by repurposing fingolimod (FTY720) leads to mitigated neuropathy and improved clinical outcome in a mouse model for Charcot-Marie-Tooth 1X disease., PMID:40239532
A dose escalation and safety study of AAVrh10-mediated Schwann cell-targeted gene therapy for CMT1X., PMID:40055046
Potential of connexin 32 as a predictive marker for drug-induced cholestatic liver injury in a collagen vitrigel-culture model of HepG2-NIAS cells, a new subline of HepG2 cells, with bile canaliculus-like structures., PMID:40024757
Genetic landscape of Charcot-Marie-Tooth disease in Vietnam: A prospective multicenter study., PMID:39973457
[Analysis of clinical and novel gene mutations with X-linked Charcot-marie-tooth disease type 1]., PMID:39956630
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis., PMID:39938686
Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis., PMID:39863862
Delineating the genetic landscape of Charcot-Marie-tooth disease in Türkiye: Distinct distribution, rare phenotypes, and novel variants., PMID:39776111
Mechanism of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate., PMID:39739741
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model., PMID:39639332
Comprehensive Analysis of GJB1 in Breast Cancer: Its Implications in Survival and Molecular Mechanisms., PMID:39626903
Physical exercise halts further functional decline in an animal model for Charcot-Marie-Tooth disease 1X at an advanced disease stage., PMID:39523026
Novel Missense Mutation in GJB1 Gene Leading to X-linked Charcot-Marie-Tooth Disease in Young Male: A Case Report., PMID:39428786
Regulation of the gap junction interplay during postnatal development in the rat epididymis., PMID:39412535
Hereditary spastic paraplegia and extensive leukoencephalopathy: a case report of a unique phenotype associated with a GJB1/Cx32 p.Pro174Ser variant., PMID:39232641
Utility of genome sequencing in exome-negative pediatric patients with neurodevelopmental phenotypes., PMID:39031459
Generation of Connexin-Expressing Stable Cell Pools., PMID:38578420
Identification and validation of a gap junction protein related signature for predicting the prognosis of renal clear cell carcinoma., PMID:38454924
Genetic diversity in hereditary axonal neuropathy: Analyzing 53 Brazilian children., PMID:38375759
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury., PMID:38347637
Changes in Expression of Key Genes in Alzheimer's Disease: A Specific Brain Tissue Change., PMID:38267766
Role of connexin 32 in the directional differentiation of induced pluripotent stem cells into hepatocytes., PMID:38250613
Mutational screening of Greek patients with axonal Charcot-Marie-Tooth disease using targeted next-generation sequencing: Clinical and molecular spectrum delineation., PMID:37747677
Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels., PMID:37647412
Gene replacement therapy in two Golgi-retained CMT1X mutants before and after the onset of demyelinating neuropathy., PMID:37645436
Two new mouse models of Gjb1-associated Charcot-Marie-Tooth disease type 1X., PMID:37551045
Spatial Fluctuation of Central Nervous System Lesions in X-linked Charcot-Marie-Tooth Disease with a Novel GJB1 Mutation., PMID:37407465
Dietary berberine against intestinal oxidative stress, inflammation response, and microbiota disturbance caused by chronic copper exposure in freshwater grouper (Acrossocheilus fasciatus)., PMID:37385463
Genetic analysis and natural history of Charcot-Marie-Tooth disease CMTX1 due to GJB1 variants., PMID:37284795
Mechanisms of Diseases Associated with Mutation in GJC2/Connexin 47., PMID:37189458
A new IRES-mediated truncated Cx32 isoform inhibits global mRNA translation to suppress glioblastoma., PMID:36931032
Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease., PMID:36926710
Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration., PMID:36835202
Novel Variants in MPV17, PRX, GJB1, and SACS Cause Charcot-Marie-Tooth and Spastic Ataxia of Charlevoix-Saguenay Type Diseases., PMID:36833258
Charcot-Marie-Tooth Disease with a Novel Variant in Gap Junction Protein Beta 1 Presenting with Visual Field Defects., PMID:36792185
Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1., PMID:36601735
Novel mutation in the MPZ gene causes early-onset but slow-progressive Charcot-Marie-Tooth disease in a Russian family: a case report., PMID:36567457
Hyperglycaemia-induced impairment of the autorhythmicity and gap junction activity of mouse embryonic stem cell-derived cardiomyocyte-like cells., PMID:36547741
Knock-in mouse models for CMTX1 show a loss of function phenotype in the peripheral nervous system., PMID:36403785
Identification of a rare missense mutation in GJB1 and prenatal diagnosis in a Chinese family with CMT: A case report., PMID:36397455
A novel splicing mutation in 5'UTR of GJB1 causes X-linked Charcot-Marie-tooth disease., PMID:36394156
[Genetic distribution in Chinese patients with hereditary peripheral neuropathy]., PMID:36241230
Novel mutations in GJB1 trigger intracellular aggregation and stress granule formation in X-linked Charcot-Marie-Tooth Disease., PMID:36225735
[Clinical and genetic analysis of a child with disorder of sex development]., PMID:35929938
Connexin32 regulates expansion of liver cancer stem cells via the PI3K/Akt signaling pathway., PMID:35894130
Alterations in connexin 43 gene and protein expression in the chicken oviduct following tamoxifen treatment., PMID:35689942
Molecular characterization of Turkish patients with demyelinating Charcot-Marie-Tooth disease., PMID:35562614
For research use only. Not for human or drug use.
