Catalog No.
YHC14101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln39-Asn74
Predicted molecular weight
32.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P05141
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenine nucleotide translocator 2, Solute carrier family 25 member 5, ADP,ATP carrier protein 2, ADP,ATP carrier protein, fibroblast isoform, ADP/ATP translocase 2, SLC25A5, AAC2, ANT2, ANT 2
Adenine nucleotide translocase 2 silencing promotes metabolic reprogramming in P19 embryonal carcinoma stem cells., PMID:40381816
Metabolic reprogramming driven by Ant2 deficiency augments T Cell function and anti-tumor immunity in mice., PMID:40341170
ETS2 aggravate allergic airway inflammation by regulating ANT2-mediated cytosolic mitochondrial DsRNA levels., PMID:40275330
Combined transcriptomic and proteomic analyses reveal relevant myelin features in mice with ischemic stroke., PMID:40085348
Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia., PMID:39916955
CgANT2 regulates mitophagy of oyster haemocyte response against bacterial stimulation., PMID:39613199
Tumor-derived extracellular vesicles convey solute transporters to induce bioenergetic dependence shift contributing to treatment resistance., PMID:39431017
GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia., PMID:39327432
ANT2: the first mammalian mitochondrial RNA transport translocon., PMID:38914843
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca2+ and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy., PMID:38873928
Exploring the multifaceted role of adenosine nucleotide translocase 2 in cellular and disease processes: A comprehensive review., PMID:38857656
ANT2 functions as a translocon for mitochondrial cross-membrane translocation of RNAs., PMID:38811766
The CC2D2B is a novel genetic modifier of the clinical phenotype in patients with hereditary angioedema due to C1 inhibitor deficiency., PMID:38679185
TR-57 Treatment of SUM159 Cells Induces Mitochondrial Dysfunction without Affecting Membrane Potential., PMID:38256264
Embryonic exposure to aluminum chloride blocks the onset of spermatogenesis through disturbing the dynamics of testicular tight junctions via upregulating Slc25a5 in offspring., PMID:38242464
Adenine nucleotide translocase 2 (Ant2) is required for individualization of spermatogenesis of Drosophila melanogaster., PMID:38112480
Lysine β-hydroxybutyrylation promotes lipid accumulation in alcoholic liver disease., PMID:38012969
Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis., PMID:37487137
Dynamin-like Protein 1 (DNML1) as a Molecular Target for Antibody-Based Immunotherapy to Treat Glaucoma., PMID:36362420
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma., PMID:36346110
Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats., PMID:36030297
Whole-Genome Sequencing Identified KCNJ12 and SLC25A5 Mutations in Port-Wine Stains., PMID:35935790
Gene Expression Characteristics of Tumor and Adjacent Non-Tumor Tissues of Pancreatic Ductal Adenocarcinoma (PDAC) In-Silico., PMID:35891953
Construction of Prediction Model for Atrial Fibrillation with Valvular Heart Disease Based on Machine Learning., PMID:39076905
The mitochondrial adenine nucleotide transporters in myogenesis., PMID:35714845
Preparation and Application of a Chemical Probe for Identifying the Targets of the Marine Cyclic Peptide Kapakahine A., PMID:35164336
Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells., PMID:35109789
Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma., PMID:35082402
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG., PMID:34983179
Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria., PMID:34849563
ANT2 drives proinflammatory macrophage activation in obesity., PMID:34676827
Quantitative proteomic analysis of trachea in fatting pig exposed to ammonia., PMID:34302998
The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein., PMID:34234233
The plasma peptides of Alzheimer's disease., PMID:34182925
Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers., PMID:33396658
Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure., PMID:33382739
ANT2-Mediated ATP Import into Mitochondria Protects against Hypoxia Lethal Injury., PMID:33255741
The Effect of Deflazacort Treatment on the Functioning of Skeletal Muscle Mitochondria in Duchenne Muscular Dystrophy., PMID:33228255
Antimicrobial Peptide TP4 Targets Mitochondrial Adenine Nucleotide Translocator 2., PMID:32784874
Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias., PMID:32515122
Delineation of Clinical Manifestations of the Inherited Xq24 Microdeletion Segregating with sXCI in Mothers: Two Novel Cases with Distinct Phenotypes Ranging from UBE2A Deficiency Syndrome to Recurrent Pregnancy Loss., PMID:32485717
Sodium butyrate opens mitochondrial permeability transition pore (MPTP) to induce a proton leak in induction of cell apoptosis., PMID:32423794
Increased Protein S-Glutathionylation in Leber's Hereditary Optic Neuropathy (LHON)., PMID:32344771
Mitochondrial PAK6 inhibits prostate cancer cell apoptosis via the PAK6-SIRT4-ANT2 complex., PMID:32194820
Duchenne muscular dystrophy is associated with the inhibition of calcium uniport in mitochondria and an increased sensitivity of the organelles to the calcium-induced permeability transition., PMID:31926263
Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity., PMID:31528845
Tissue-specific dysregulation of mitochondrial respiratory capacity and coupling control in colon-26 tumor-induced cachexia., PMID:31017805
The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex are conserved across multiple cell lines., PMID:30828972
Down-regulated lncRNA SLC25A5-AS1 facilitates cell growth and inhibits apoptosis via miR-19a-3p/PTEN/PI3K/AKT signalling pathway in gastric cancer., PMID:30793479
ANT2 mediates hypoxia and inflammation in obesity., PMID:30531919
For research use only. Not for human or drug use.
