Catalog No.
YHB78001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn20-Asn103
Predicted molecular weight
21.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95868
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MEGT1, G6D, Megakaryocyte-enhanced gene transcript 1 protein, NG25, LY6G6D, C6orf23, Protein Ly6-D, Lymphocyte antigen 6 complex locus protein G6d
Shengqiyichang decoction regulates antitumor immunity in colorectal cancer by downregulating lymphocyte antigen 6 family member G6D via the protein kinase B/p38 mitogen-activated protein kinase signaling pathway., PMID:39524806
Decoding LY6G6D in colorectal cancer: Unraveling biomarker potential and therapeutic insights., PMID:38836687
Clinical and Immunologic Characteristics of Colorectal Cancer Tumors Expressing LY6G6D., PMID:38791382
Cytosolic nucleic acid sensing and mitochondrial transcriptomic changes as early triggers of metabolic disease in db/db mice., PMID:37979047
MHC class III lymphocyte antigens 6 as endogenous immunotoxins: Unlocking immunotherapy in proficient mismatch repair colorectal cancer., PMID:37818781
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager., PMID:36159851
Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer., PMID:35364611
Alterations of 5-hydroxymethylcytosines in circulating cell-free DNA reflect retinopathy in type 2 diabetes., PMID:33221518
JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer., PMID:30670049
Cell-surface markers for colon adenoma and adenocarcinoma., PMID:26894861
[Detection of LY6G6D gene exon-intron structure,]., PMID:19807019
Regulation of expression of two LY-6 family genes by intron retention and transcription induced chimerism., PMID:18817541
Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands., PMID:17008713
For research use only. Not for human or drug use.
