Catalog No.
YMB90001
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Asn679-Arg755
Predicted molecular weight
21.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06684
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complement C5, Hemolytic complement, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, C5, Hc
Epidemiological characteristics of adenovirus in children in Yancheng, China, 2023-2024., PMID:40510801
Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica., PMID:40506785
Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models., PMID:40496615
Precision-Engineered Nano-Electrospray Emitters Enhance Ionization Efficiency for Trap-Assisted Direct Infusion Mass Spectrometry: Application in Plasma Alzheimer's Disease Proteomics., PMID:40490927
[Diagnosis, treatment, and genetic analysis of five cases of primary atypical hemolytic uremic syndrome]., PMID:40484823
Aptamers as therapeutic targets: prospects and progress in the treatment of cancers., PMID:40479828
Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches., PMID:40473811
Characterization and differential expression of DNA methyltransferase and demethylase genes in response to abiotic stress in Isodon rubescens., PMID:40468179
TRIM56 enhances adenoviral E1A steady state to improve oncolytic adenovirus therapy efficacy., PMID:40459263
Complement inhibitor therapy as a steroid-sparing strategy in generalized myasthenia gravis., PMID:40453104
Characterisation of the thermophilic P450 CYP116B305 identified using metagenomics-derived sequence data from an Australian hot spring., PMID:40450052
A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction., PMID:40449486
Recent Findings in N6-Methyladenosine Modification and Significance in Pancreatic Cancer., PMID:40448344
A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS)., PMID:40448185
Oral iptacopan monotherapy in paroxysmal nocturnal haemoglobinuria: final 48-week results from the open-label, randomised, phase 3 APPLY-PNH trial in anti-C5-treated patients and the open-label, single-arm, phase 3 APPOINT-PNH trial in patients previously untreated with complement inhibitors., PMID:40447351
Isolation and Characterization of E8 Monoclonal Antibodies from Donors Vaccinated with Recombinant Vaccinia Vaccine with Efficient Neutralization of Authentic Monkeypox Virus., PMID:40432083
Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates., PMID:40424786
Construction and Modification of an Efficient Whole-Cell Catalyst for 5-Aminolevulinic Acid Using Induced Protoporphyrin IX as a Marker., PMID:40424032
The Role of Complement in the Pathogenesis and Treatment of Myasthenia Gravis., PMID:40422242
Fibroblast reprogramming in the dura mater of NTG-induced migraine-related chronic hypersensitivity model drives monocyte infiltration via Angptl1-dependent stromal signaling., PMID:40419944
Differential analysis of core complement components expression and localization across rodent, non-human primate, and human ocular tissues., PMID:40419209
Proteomic profiling of serum small extracellular vesicles predicts post-COVID syndrome development., PMID:40419011
Validation for soluble C5b-9 detection and comparative analysis of three quantification methods., PMID:40412754
Long-lasting expression of FosB/ΔFosB immunoreactivity following acute stress in the paraventricular and supraoptic nuclei of the rat hypothalamus., PMID:40412556
Investigating the role of complement 5a in systemic bone loss after myocardial infarction., PMID:40412474
Combination of miRNA148a-3p binding sites and C5-12 promoter in rAAV vector synergistically reduces antigen presentation and transgene immunity., PMID:40404114
Intensified human activities shape the dynamics of sediment organic matter in a highly-disturbed estuary., PMID:40398278
The Protein Kinase Inhibitor, Tyrphostin AG126, and Its Derivatives Suppress Phosphorylation of Plasma Membrane H+-ATPase and Light-Induced Stomatal Opening., PMID:40396646
Isolation and validation of antimalarial compounds from Phyllanthus emblica leaves for new antimalarial drug development., PMID:40394223
Discovery of an Orally Bioavailable and Brain Penetrant Selective Estrogen Receptor Degrader., PMID:40393772
Storage and in-use stability of an excipient enhanced growth (EEG) synthetic lung surfactant powder formulation., PMID:40392626
Serum biomarkers of collagen remodeling are associated with intestinal fibrosis and differentiate stenotic from luminal Crohn's disease patients: a pre- and post-resection longitudinal study., PMID:40391838
Hydrophobic Interactions in Aqueous Osmolyte Solutions: Thermodynamics of Solvation and Implication on Protein Stability., PMID:40387874
Inhibition of Alternative and Terminal Complement Pathway Components Modulate the Immune Response Against Bacteria and Fungi in Whole Blood., PMID:40387159
Modulation of TTR gene expression in the eye using modified siRNAs., PMID:40386915
The FvMYB17 targets FvDHQS to promote ellagic acid biosynthesis in strawberry., PMID:40384433
Transcriptome sequencing of Antheraea pernyi antennae for identification of olfactory-related genes., PMID:40383784
Analysis of CD22 cis-ligands using a synthetic sialoside binding to CD22 with ultra-high affinity., PMID:40381245
Complement levels and their diagnostic utility in neonatal sepsis., PMID:40380203
PLASMIC score to aid diagnosis of aHUS: an analysis of C5 inhibitor clinical trials and the PINC AI™ healthcare database., PMID:40375186
Non-canonical extracellular complement pathways and the complosome paradigm in cancer: a scoping review., PMID:40370471
Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis., PMID:40370446
Transient transfection using 222 nm far UV-C irradiation., PMID:40368969
Ravulizumab for generalized Myasthenia Gravis: a multicenter real-life experience., PMID:40366475
Staphylococcus aureus SaeR/S-regulated factors overcome human complement-mediated inhibition of aggregation to evade neutrophil killing., PMID:40359050
[Mahuang Lianqiao Chixiaodou Decoction and its active components inhibit alternative pathway complement activation in rat model of IgA nephropathy]., PMID:40350950
Design, synthesis, anticancer activity evaluation and molecular dynamics study of pyrazine N-oxide-based SHP2 allosteric inhibitors., PMID:40344735
Eculizumab in severe pediatric STEC-HUS and its impact on neurological prognosis-a systematic review and meta-analysis., PMID:40341411
Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis., PMID:40338657
Recent analytical advances in the detection and characterization of 3-O-sulfated heparan sulfate., PMID:40328973
For research use only. Not for human or drug use.
