Catalog No.
EHB91101
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Met1-Val186
Predicted molecular weight
24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01116-2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Isoform 2B of GTPase KRas, 3.6.5.2, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2
Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms., PMID:40506614
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction., PMID:40504949
GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer., PMID:40503938
Computational design of conformation-biasing mutations to alter protein functions., PMID:40501788
An Advanced IVB Lung Adenocarcinoma Patient With KRAS Mutations, Benefited From Camrelizumab Combined With Anti-Angiogenic Agents for Therapy: A Case Report., PMID:40488279
Erianin inhibits the proliferation and stemness of pancreatic cancer cells by interacting with MEK1/2., PMID:40484042
Indoleamine 2,3-dioxygenase-1 expression in non-small-cell lung cancer: analyses of prevalence, clinical correlations and prognostic impact in 2 large patient cohorts., PMID:40475772
KRAS/NRAS variants and copy number alterations prognostically stratify patients with sinonasal melanoma., PMID:40474710
Comprehensive morphological, immunohistochemical, and molecular characterization of congenital pulmonary airway malformation (CPAM)., PMID:40473982
RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids., PMID:40470182
Retrospective stratified analysis of resistance mechanisms to anti-EGFR therapy in mCRC using tumor tissue samples., PMID:40467730
MAGNET-seq: A tandem PCR and hybrid capture method for enhanced target enrichment., PMID:40465784
Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers., PMID:40465692
[Genetic and clinical characteristics of children with RAS-mutated juvenile myelomonocytic leukemia]., PMID:40462427
Circulating tumor DNA dynamic variation predicts sotorasib efficacy in KRASp.G12C-mutated advanced non-small cell lung cancer., PMID:40445863
Factors affecting survival prognosis of patients with rectal cancer after neoadjuvant chemoradiotherapy., PMID:40444087
Macrophage activation determines muscle wasting in pancreatic cancer., PMID:40442475
Combination therapy of avutometinib and MRTX1133 synergistically suppresses cell growth by inducing apoptosis in KRASG12D-mutated pancreatic cancer., PMID:40439998
Dauricine Impedes the Tumorigenesis of Lung Adenocarcinoma by Regulating Nrf2 and Reactive Oxygen Species., PMID:40422202
Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidates., PMID:40421426
The subcellular distribution of phosphorylated Y-box-binding protein-1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features., PMID:40420381
HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity., PMID:40419509
A novel KRAS exon 2 drop-off digital PCR assay for mutation detection in cell-free DNA of cancer patients., PMID:40413426
Neoadjuvant PD-1 and PD-L1 Blockade With Chemotherapy for Borderline Resectable and Unresectable Stage III Non-Small Cell Lung Cancer., PMID:40402502
Genetic and Phenotypic correlates of clinical outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN study., PMID:40396900
Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site., PMID:40395209
Metformin and chloroquine enhanced the efficacy of cytarabine in acute lymphoblastic leukemia cell lines: a drug repositioning approach., PMID:40360710
Regional distribution of HLA frequencies in the USA: implications for TCR-based therapies., PMID:40360437
Dual inhibition of GTP-bound KRAS and mTOR in lung adenocarcinoma and squamous cell carcinoma harboring KRAS G12C., PMID:40350441
Norepinephrine mediates adrenergic receptor transcription and oncogenic gene expression in pancreatic ductal adenocarcinoma., PMID:40349604
Equalizing prognostic disparities in KRAS-mutated stage III NSCLC patients: addition of durvalumab to combined chemoradiotherapy improves survival., PMID:40349418
Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer., PMID:40340861
Targeting the SHOC2-RAS interaction in RAS-mutant cancers., PMID:40335703
Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression., PMID:40334547
A comprehensive analysis identified an autophagy-related risk model for predicting recurrence and immunotherapy response in stage I lung adenocarcinoma., PMID:40330698
Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development., PMID:40327534
RAS gene polymorphisms confer the risk of neuroblastoma in Chinese children from Jiangsu province., PMID:40323475
NMR 1H, 13C, and 15N resonance assignments of the oncogenic Q61R variant of human NRAS in the active, GTP-bound conformation., PMID:40316884
Prognostic Properties of KRAS Gene Mutation Subtypes in Resected Pancreatic Ductal Adenocarcinoma., PMID:40314742
MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids., PMID:40314454
Napsin A as a key prognostic biomarker in spinal metastases of lung cancer: implications for survival and neurological function., PMID:40311196
Cell cycle duration determines oncogenic transformation capacity., PMID:40307557
GENETIC ALTERATIONS IN TUBO-OVARIAN EPITHELIUM DURING OVARIAN NEOPLASIA., PMID:40305800
[Primary ovarian mesonephric-like adenocarcinoma: a clinicopathological analysis of 17 cases]., PMID:40302579
Identification and characterization of oncogenic KRAS G12V inhibitory peptides by phage display, molecular docking and molecular dynamic simulation., PMID:40300294
The role of MLH1, MSH2 and MSH6 in the development of colorectal cancer in Uganda., PMID:40295928
Piperine derivative, (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-(2-hydroxyphenyl)penta-2,4-dienamide, exerted cytotoxic activity toward MCF-7 breast cancer cells via Apoptosis: Gene expression and biomolecular change study., PMID:40294461
Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells., PMID:40289347
Antitumor platinum(II) complex 56MESS binds to DNA G-quadruplexes, downregulates expression of c-MYC and k-RAS oncogenes, and triggers DNA damage in cancer cells., PMID:40288436
For research use only. Not for human or drug use.
