Catalog No.
YVV20801
Expression system
E. coli
Species
Human papillomavirus type 16
Protein length
Arg2-Ala473
Predicted molecular weight
79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03107
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Minor capsid protein L2, L2
Cell-Free Expression of HPV16 Minor Capsid Protein L2 and Its Interaction with S100A10., PMID:40415288
TAGLN2-mediated Actin Cytoskeleton Stabilization Promotes Proliferation and Metastasis of Ovarian Carcinoma., PMID:40247723
HPV16 entry requires dynein for minus-end transport and utilizes kinesin Kif11 for plus-end transport along microtubules during mitosis., PMID:39629998
Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility., PMID:39572555
Rab6a enables BICD2/dynein-mediated trafficking of human papillomavirus from the trans-Golgi network during virus entry., PMID:39431827
Immunoinformatics approach for design novel multi-epitope prophylactic and therapeutic vaccine based on capsid proteins L1 and L2 and oncoproteins E6 and E7 of human papillomavirus 16 and human papillomavirus 18 against cervical cancer., PMID:39039819
A peptide derived from sorting nexin 1 inhibits HPV16 entry, retrograde trafficking, and L2 membrane spanning., PMID:38909779
The BICD2 dynein cargo adaptor binds to the HPV16 L2 capsid protein and promotes HPV infection., PMID:38829892
A Peptide Derived from Sorting Nexin 1 Inhibits HPV16 Entry, Retrograde Trafficking, and L2 Membrane Spanning., PMID:38826391
Advances on two serological assays for human papillomavirus provide insights on the reactivity of antibodies against a cross-neutralization epitope of the minor capsid protein L2., PMID:38022617
Sequence-independent activity of a predicted long disordered segment of the human papillomavirus type 16 L2 capsid protein during virus entry., PMID:37819982
Alum and a TLR7 agonist combined with built-in TLR4 and 5 agonists synergistically enhance immune responses against HPV RG1 epitope., PMID:37798448
Crystal Structures of Plk1 Polo-Box Domain Bound to the Human Papillomavirus Minor Capsid Protein L2-Derived Peptide., PMID:37684534
Sequence independent activity of a predicted long disordered segment of the human papillomavirus L2 capsid protein during virus entry., PMID:36993745
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16., PMID:36815785
Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas., PMID:36680181
Next generation L2-based HPV vaccines cross-protect against cutaneous papillomavirus infection and tumor development., PMID:36263027
Detection of HPV16 viral load in L2 gene as a related predictor of cervical cancer among women in Dhi-Qar province by qRT-PCR., PMID:36214947
HPV16 Induces Formation of Virus-p62-PML Hybrid Bodies to Enable Infection., PMID:35891458
Human Papillomavirus Type 16 L2 Gene Sequence Variation Analysis in Indonesian Cervical Cancer Specimens., PMID:35763643
RG2-VLP: a Vaccine Designed to Broadly Protect against Anogenital and Skin Human Papillomaviruses Causing Human Cancer., PMID:35703545
Human Papillomavirus Minor Capsid Protein L2 Mediates Intracellular Trafficking into and Passage beyond the Endoplasmic Reticulum., PMID:35608352
Genetic variability in minor capsid protein (L2 gene) of human papillomavirus type 16 among Indian women., PMID:35552511
Human Papillomavirus L2 Capsid Protein Stabilizes γ-Secretase during Viral Infection., PMID:35458534
Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine., PMID:35139303
HPV16 Entry into Epithelial Cells: Running a Gauntlet., PMID:34960729
Identification of heterogenous nuclear ribonucleoproteins (hnRNPs) and serine- and arginine-rich (SR) proteins that induce human papillomavirus type 16 late gene expression and alter L1 mRNA splicing., PMID:34860285
A respirable HPV-L2 dry-powder vaccine with GLA as amphiphilic lubricant and immune-adjuvant., PMID:34740725
Cryo EM Analysis Reveals Inherent Flexibility of Authentic Murine Papillomavirus Capsids., PMID:34696452
Designing a therapeutic and prophylactic candidate vaccine against human papillomavirus through vaccinomics approaches., PMID:34547435
Immunological responses and anti-tumor effects of HPV16/18 L1-L2-E7 multiepitope fusion construct along with curcumin and nanocurcumin in C57BL/6 mouse model., PMID:34516991
In Silico Design and Immunological Studies of Two Novel Multiepitope DNA-Based Vaccine Candidates Against High-Risk Human Papillomaviruses., PMID:34308516
Mutation Profiles, Glycosylation Site Distribution and Codon Usage Bias of Human Papillomavirus Type 16., PMID:34209097
Computational Modeling of Immune Response Triggering Immunogenic Peptide Vaccine Against the Human Papillomaviruses to Induce Immunity Against Cervical Cancer., PMID:33973819
RG1-VLP and Other L2-Based, Broad-Spectrum HPV Vaccine Candidates., PMID:33802456
Human Papillomavirus infection requires the CCT Chaperonin Complex., PMID:33731457
Improvement of RG1-VLP vaccine performance in BALB/c mice by substitution of alhydrogel with the next generation polyphosphazene adjuvant PCEP., PMID:33573433
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility., PMID:33568731
A Scalable Manufacturing Approach to Single Dose Vaccination against HPV., PMID:33478147
Optimization of RG1-VLP vaccine performance in mice with novel TLR4 agonists., PMID:33309485
Human Papillomavirus 16 L2 Recruits both Retromer and Retriever Complexes during Retrograde Trafficking of the Viral Genome to the Cell Nucleus., PMID:33177206
Comprehensive Assessment of the Antigenic Impact of Human Papillomavirus Lineage Variation on Recognition by Neutralizing Monoclonal Antibodies Raised against Lineage A Major Capsid Proteins of Vaccine-Related Genotypes., PMID:32967963
Optimized production strategy of the major capsid protein HPV 16L1 non-assembly variant in E. coli., PMID:32681956
Correlation between cervical HPV DNA detection and HPV16 seroreactivity measured with L1-only and L1+L2 viral capsid antigens., PMID:32510304
The possible regions to design Human Papilloma Viruses vaccine in Iranian L1 protein., PMID:32435064
Cell-penetrating peptide inhibits retromer-mediated human papillomavirus trafficking during virus entry., PMID:32123072
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines., PMID:31819523
Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome., PMID:31743367
Production and Preliminary In Vivo Evaluations of a Novel in silico-designed L2-based Potential HPV Vaccine., PMID:31729940
In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine., PMID:31645650
For research use only. Not for human or drug use.
