Catalog No.
PHH11501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SPA17 (Met1-Gln143).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CT22,SPA17,Sp17-1,SP17,Cancer/testis antigen 22,Sperm surface protein Sp17,Sperm autoantigenic protein 17,Sperm protein 17
Purification
Purified by antigen affinity column.
Accession
Q15506
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Sperm protein antigen 17 and Sperm flagellar 1 cancer testis antigens are expressed in a rare case of ciliated foregut cyst of the common hepatic duct., PMID:37224658
Serum Sp17 Autoantibody Serves as a Potential Specific Biomarker in Patients with SAPHO Syndrome., PMID:33392854
Immunogenicity and contraceptive efficacy of recombinant fusion protein encompassing Sp17 spermatozoa-specific protein and GnRH: Relevance of adjuvants and microparticles based delivery to minimize number of injections., PMID:31845450
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities., PMID:31218705
Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study., PMID:30309325
Novel Sperm and Gonadotropin-releasing Hormone-based Recombinant Fusion Protein: Achievement of 100% Contraceptive Efficacy by Co-immunization of Male and Female Mice., PMID:27676172
Mapping T and B cell epitopes in sperm protein 17 to support the development of an ovarian cancer vaccine., PMID:26263201
Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets., PMID:25739119
Increased levels of sperm protein 17 mRNA and circulating antibodies in periampullary carcinoma patients., PMID:25348194
Anti-Sp17 monoclonal antibody-doxorubicin conjugates as molecularly targeted chemotherapy for ovarian carcinoma., PMID:23943313
Sperm protein 17, MAGE-C1 and NY-ESO-1 in hepatocellular carcinoma: expression frequency and their correlation with clinical parameters., PMID:23923079
Anti-Sp17 monoclonal antibody with antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity activities against human ovarian cancer cells., PMID:22198696
In vivo molecular targeting effects of anti-Sp17- ICG-Der-02 on hepatocellular carcinoma evaluated by an optical imaging system., PMID:21366930
Sperm protein 17 is highly expressed in endometrial and cervical cancers., PMID:20712874
[Biological activity assays and cellular imaging of anti-human sperm protein 17 immunomagnetic nanoparticles]., PMID:19900363
A yeast two-hybrid system using Sp17 identified Ropporin as a novel cancer-testis antigen in hematologic malignancies., PMID:17551920
[Detection of anti-Sp17 antibodies in infertile patients' serum and its clinical significance]., PMID:17302030
Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer., PMID:17230514
[Preparation and characterization of the monoclonal antibody against human sperm protein 17]., PMID:16948914
[Development of radioimmunoassay for human sperm protein 17]., PMID:16833189
Changes in intracellular distribution and activity of protein phosphatase PP1gamma2 and its regulating proteins in spermatozoa lacking AKAP4., PMID:15385410
Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella., PMID:15257753
Expression of sperm protein 17 (Sp17) in ovarian cancer., PMID:14712480
Tumor vaccine for ovarian carcinoma targeting sperm protein 17., PMID:12015770
Sperm protein 17 is not expressed on normal leukocytes., PMID:12001904
Sperm protein 17 is expressed on normal and malignant lymphocytes and promotes heparan sulfate-mediated cell-cell adhesion., PMID:11568003
Sperm protein 17 (Sp17) in multiple myeloma: opportunity for myeloma-specific donor T cell infusion to enhance graft-versus-myeloma effect without increasing graft-versus-host disease risk., PMID:11477539
Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma., PMID:11222401
A chimeric sperm peptide induces antibodies and strain-specific reversible infertility in mice., PMID:9716550
Immune response to immunization with sperm antigens in the macaque oviduct., PMID:9510968
Sequence and characterization of the sperm protein Sp17 from the baboon., PMID:9110316
Autoimmunogenicity of the human sperm protein Sp17 in vasectomized men and identification of linear B cell epitopes., PMID:9022615
Sequence and localization of the mouse sperm autoantigenic protein, Sp17., PMID:7578682
Sequence of a rabbit sperm zona pellucida binding protein and localization during the acrosome reaction., PMID:7525387
For research use only. Not for human or drug use.
