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Anti-Norovirus/Norwalk virus Major capsid protein/VP1 Antibody (A1431)

Catalog #:   RVV25607 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1
Applications: ELISA, Neutralization
Accession: R4I4P2
Overview

Catalog No.

RVV25607

Species reactivity

Norovirus Hu/GII.4/Farmington Hills/2004/USA

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

Major capsid protein

Concentration

0.13 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

R4I4P2

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

A1431

Data Image
References

Highly variable antigenic site located at the apex of GII.4 norovirus capsid protein induces cross-reactive blocking antibodies in a variant-specific manner., PMID:40444947

Manipulation of immunodominant variable epitopes of norovirus capsid protein elicited cross-blocking antibodies to different GII.4 variants despite the low potency of the polyclonal sera., PMID:40444946

An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial., PMID:40043138

Broadly neutralizing antibodies targeting pandemic GII.4 variants or seven GII genotypes of human norovirus., PMID:40043137

Vaccinia Virus Vector Bivalent Norovirus Vaccine., PMID:40006992

Effect of trypsin digestion on the integrity and antigenic epitopes of GII.6 norovirus virus-like particles., PMID:39762616

H and B Blood Antigens Are Essential for In Vitro Replication of GII.2 Human Norovirus., PMID:39758750

Two Monoclonal Antibodies Targeting Distinct Subdomains of Human Norovirus P Protein., PMID:39463379

Replication-deficient Sendai virus expressing human norovirus capsid protein elicits robust NoV-specific antibody and T-cell responses in mice., PMID:39236991

A quadrivalent norovirus vaccine based on a chimpanzee adenovirus vector induces potent immunity in mice., PMID:38997087

Identification of a norovirus GII-specific antigenic epitope., PMID:38819530

Structural analyses of the GI.4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies., PMID:38593321

Identification of a GII.6 norovirus blockade antibody epitope., PMID:37392840

Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response., PMID:37280322

Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies., PMID:36971561

Minimal Antigenic Evolution after a Decade of Norovirus GII.4 Sydney_2012 Circulation in Humans., PMID:36688654

High yield production of norovirus GII.4 virus-like particles using silkworm pupae and evaluation of their protective immunogenicity., PMID:36528444

Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein., PMID:36389818

Generation of Recombinant Rotaviruses Expressing Human Norovirus Capsid Proteins., PMID:36314817

Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions., PMID:35680964

Dynamic immunodominance hierarchy of neutralizing antibody responses to evolving GII.4 noroviruses., PMID:35417705

Recombinant norovirus capsid protein VP1 (GII.4) expressed in H5 insect cells exhibits post-translational modifications with potential impact on lectin activity and vaccine design., PMID:35312780

Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology., PMID:34894525

Multiple Signals in the Gut Contract the Mouse Norovirus Capsid To Block Antibody Binding While Enhancing Receptor Affinity., PMID:34468172

Antigenic cartography reveals complexities of genetic determinants that lead to antigenic differences among pandemic GII.4 noroviruses., PMID:33836574

A Norovirus Uses Bile Salts To Escape Antibody Recognition While Enhancing Receptor Binding., PMID:33827952

Linear B-Cell Epitopes in Human Norovirus GII.4 Capsid Protein Elicit Blockade Antibodies., PMID:33466932

RNA-assisted self-assembly of monomeric antigens into virus-like particles as a recombinant vaccine platform., PMID:33465537

Broad-range and effective detection of human noroviruses by colloidal gold immunochromatographic assay based on the shell domain of the major capsid protein., PMID:33430771

Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus., PMID:32321816

Genotype-Specific Neutralization of Norovirus Is Mediated by Antibodies Against the Protruding Domain of the Major Capsid Protein., PMID:32179892

Production and characterization of monoclonal antibodies against GII.6 norovirus virus-like particles., PMID:32109570

Immunogenicity and protective potency of Norovirus GII.17 virus-like particle-based vaccine., PMID:32088791

Genomic and biological characterization of a pandemic norovirus variant GII.4 Sydney 2012., PMID:31912284

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients., PMID:31656022

Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus., PMID:31585726

Population Genomics of GII.4 Noroviruses Reveal Complex Diversification and New Antigenic Sites Involved in the Emergence of Pandemic Strains., PMID:31551337

Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein., PMID:31100802

The Antigenic Topology of Norovirus as Defined by B and T Cell Epitope Mapping: Implications for Universal Vaccines and Therapeutics., PMID:31083353

The Dynamic Capsid Structures of the Noroviruses., PMID:30857192

GII.4 Human Norovirus: Surveying the Antigenic Landscape., PMID:30791623

Linear epitope binding antibodies against GII.3 Norovirus exhibit no histo-blood group antigens (HBGAs) blocking effects., PMID:30725444

Structural Basis of Nanobodies Targeting the Prototype Norovirus., PMID:30602609

Norovirus GII.17 Virus-Like Particles Bind to Different Histo-Blood Group Antigens and Cross-React with Genogroup II-Specific Mouse Sera., PMID:30431404

Quantifying the binding stoichiometry and affinity of histo-blood group antigen oligosaccharides for human noroviruses., PMID:29562255

Characterization of a Norovirus-specific monoclonal antibody that exhibits wide spectrum binding activities., PMID:29236287

Comprehensive characterization of a major capsid protein derived from a documented GII.6 norovirus strain., PMID:28866835

Expression and purification of norovirus virus like particles in Escherichia coli and their immunogenicity in mice., PMID:28802994

A Luciferase Immunoprecipitation System (LIPS) assay for profiling human norovirus antibodies., PMID:28673856

Expression and characterization of the major capsid protein derived from a GII.6 norovirus strain isolated in China., PMID:28219831

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Norovirus/Norwalk virus Major capsid protein/VP1 Antibody (A1431) [RVV25607]
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