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Anti-Human IL25/IL17E Antibody (ABM109.2)

Catalog #:   RHJ55503 Specific References (45) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA
Accession: Q9H293
Overview

Catalog No.

RHJ55503

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E, UNQ3120/PRO10272

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9H293

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

ABM109.2

Data Image
  • Bioactivity
    Detects Human IL25/IL17E in indirect ELISAs.
References

Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders., PMID:39875232

IL-25 Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor., PMID:39829150

First-in-human study on tolerability, pharmacokinetics and pharmacodynamics of single and multiple escalating doses of XKH001, a recombinant humanized monoclonal antibody against IL-25 in healthy Chinese volunteers., PMID:39815604

Inhibition of IL-25/IL-17RA improves immune-related adverse events of checkpoint inhibitors and reveals antitumor activity., PMID:38519059

Serum alarmins and the risk of incident interstitial lung disease in rheumatoid arthritis., PMID:37812235

IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632

Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles., PMID:35316278

IL-25 promotes trophoblast proliferation and invasion via binding with IL-17RB and associated with PE., PMID:34264790

Interleukin-25: New perspective and state-of-the-art in cancer prognosis and treatment approaches., PMID:34128588

IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology., PMID:32174926

IL-17A in Psoriasis and Beyond: Cardiovascular and Metabolic Implications., PMID:32010143

Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic Asthma: A Short Report., PMID:31885750

IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis., PMID:31885009

The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond., PMID:30127781

Macrophages are a source of IL-17 in the human placenta., PMID:29956865

Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice., PMID:29572351

A mechanism of interleukin-25 production from airway epithelial cells induced by Japanese cedar pollen., PMID:29402661

[Elevated serum IL-25 levels in rheumatoid arthritis patients with bone erosion and interstitial lung disease]., PMID:28871954

Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of Allergen., PMID:28652400

Efficacy of melatonin, IL-25 and siIL-17B in tumorigenesis-associated properties of breast cancer cell lines., PMID:28624391

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis., PMID:28246365

IL-17RB+ granulocytes are associated with airflow obstruction in asthma., PMID:27979026

IL-25 blockade inhibits metastasis in breast cancer., PMID:27909985

The signaling axis of microRNA-31/interleukin-25 regulates Th1/Th17-mediated inflammation response in colitis., PMID:27901018

Targeting IL-25 as a novel therapy in chronic rhinosinusitis with nasal polyps., PMID:27870664

IL-17 superfamily cytokines modulate normal germinal center B cell migration., PMID:27566830

Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics., PMID:27685606

Disease-specific signature of serum miR-20b and its targets IL-8 and IL-25, in myasthenia gravis patients., PMID:26845056

Brodalumab, a human anti-interleukin-17-receptor antibody in the treatment of Japanese patients with moderate-to-severe plaque psoriasis: Efficacy and safety results from a phase II randomized controlled study., PMID:26547109

IL-25 as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis., PMID:25725991

IL-17RA in intestinal inflammation: structure, signaling, function, and clinical application., PMID:25272188

Interleukin-25 induced by human chorionic gonadotropin promotes the proliferation of decidual stromal cells by activation of JNK and AKT signal pathways., PMID:24746746

IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease., PMID:24407884

IL-25 prevents T cell-mediated neurotoxicity by decreasing LFA-1 expression., PMID:24196277

The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis., PMID:23834907

IL-25 prevents and cures fulminant hepatitis in mice through a myeloid-derived suppressor cell-dependent mechanism., PMID:23564603

The interleukin-17 receptor B subunit is essential for the Th2 response to Helicobacter pylori, but not for control of bacterial burden., PMID:23533678

IL-25 improves IgA levels during parenteral nutrition through the JAK-STAT pathway., PMID:23160152

Interleukin-25 promotes basic fibroblast growth factor expression by human endothelial cells through interaction with IL-17RB, but not IL-17RA., PMID:23106660

Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity., PMID:21722219

Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses., PMID:19400908

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity., PMID:19015310

Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma., PMID:17889290

Intracellular JNK, p38 MAPK and NF-kappaB regulate IL-25 induced release of cytokines and chemokines from costimulated T helper lymphocytes., PMID:17719653

Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation., PMID:12511410

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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For research use only. Not for human or drug use.

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Anti-Human IL25/IL17E Antibody (ABM109.2) [RHJ55503]
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