Catalog No.
RHD27102
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Mac-2 antigen, Lectin L-29, LGALS3, Galactose-specific lectin 3, 35 kDa lectin, Galactoside-binding protein, CBP 35, L-31, Gal-3, Laminin-binding protein, Galectin-3, GALBP, IgE-binding protein, Carbohydrate-binding protein 35, MAC2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P17931
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
M3/38
Bioinformatics analysis of innovative multi-epitope vaccine utilizing MAGE-A, MAM-A, and Gal-3 for breast cancer management., PMID:40473741
Galectin-3 modulates cellular infectivity and inflammatory response mediated by spike protein of SARS-CoV2., PMID:40253029
Galectin-3 in metabolic disorders: mechanisms and therapeutic potential., PMID:39690058
Nanoparticle biosensors for cardiovascular disease detection., PMID:39681229
Evaluation of galectin-3 and titin in cats with a sarcomeric gene mutation associated with echocardiography., PMID:39619937
Basophils induce protumorigenic cytokines from A549 lung adenocarcinoma via mechanisms requiring IgE, galectin-3, and IL-3 priming., PMID:39432748
Gal-3 blocks the binding between PD-1 and pembrolizumab., PMID:39357979
Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients., PMID:39337398
Galectin-3 contributes to pathogenesis of IgA nephropathy., PMID:39084257
Integrated magneto-plasmonic nanostructures-based immunoassay for galectin-3 detection., PMID:39007190
Examination of the Level of Circulating Plasmablasts and Their Characteristics as Diagnostic Tools for Immunoglobulin G4-related Disease., PMID:38884310
Neutrophils impaired by anti-galectin-3 antibodies elicit inflammation of endothelial cells to aggregate the development of lupus cutaneous vasculitis., PMID:38757282
TLR2-ERK signaling pathway regulates expression of galectin-3 in a murine model of OVA-induced allergic airway inflammation., PMID:38754639
BAP31 Promotes Angiogenesis via Galectin-3 Upregulation in Neuroblastoma., PMID:38474195
Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma., PMID:38438589
Enzymatically-derived oligo-carrageenans interact with α-Gal antibodies and Galectin-3., PMID:37985065
Resistance to anti-PD-1/anti-PD-L1: galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1., PMID:37701441
Tiliroside Combined with Anti-MUC1 Monoclonal Antibody as Promising Anti-Cancer Strategy in AGS Cancer Cells., PMID:37685842
Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis., PMID:37652913
Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3., PMID:37371614
Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage., PMID:37298447
Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis., PMID:37287025
Gold nanoparticle probes for colorimetric detection of plasma galectin-3: a simple and rapid approach., PMID:37203344
An Oral Galectin Inhibitor in COVID-19-A Phase II Randomized Controlled Trial., PMID:37112643
Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy., PMID:36911262
Targeting galectin-driven regulatory circuits in cancer and fibrosis., PMID:36759557
The Expression of IL-1β Correlates with the Expression of Galectin-3 in the Tissue at the Maternal-Fetal Interface during the Term and Preterm Labor., PMID:36362749
Galectin-3 binding protein stimulated IL-6 expression is impeded by antibody intervention in SARS-CoV-2 susceptible cell lines., PMID:36220879
Anti-galectin-3 antibodies induce skin vascular inflammation via promoting local production of IL-1β in systemic lupus erythematosus., PMID:36058031
Regulatory T cells, damage-associated molecular patterns, and myeloid-derived suppressor cells in bronchoalveolar lavage fluid interlinked with chronic obstructive pulmonary disease severity: An observational study., PMID:35687771
Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy., PMID:35025017
Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling., PMID:34995420
Galectin‑3 blockade suppresses the growth of cetuximab‑resistant human oral squamous cell carcinoma., PMID:34328195
Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma., PMID:34290359
Interaction between Galectin-3 and Integrins Mediates Cell-Matrix Adhesion in Endothelial Cells and Mesenchymal Stem Cells., PMID:34067978
Serum galectin-9 could be a potential biomarker in assessing the disease activity of antineutrophil cytoplasmic antibody-associated vasculitis., PMID:34001301
Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells., PMID:33930385
Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor., PMID:33837055
Galectin-3 protects against ischemic stroke by promoting neuro-angiogenesis via apoptosis inhibition and Akt/Caspase regulation., PMID:33736511
Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity., PMID:33717655
RAGE silencing deters CML-AGE induced inflammation and TLR4 expression in endothelial cells., PMID:33639133
Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies., PMID:33580170
Inhibition of galectin-3 augments the antitumor efficacy of PD-L1 blockade in non-small-cell lung cancer., PMID:33455075
Imaging atherosclerotic plaques by targeting Galectin-3 and activated macrophages using (89Zr)-DFO- Galectin3-F(ab')2 mAb., PMID:33408786
Could Galectin-3 be a key player in the etiology of neuromyelitis optica spectrum disorder?, PMID:33309338
Polymorphic characterisation of gallinacin candidate genes and their molecular associations with growth and immunity traits in chickens., PMID:33155490
Increased serum levels of galectin-9 in patients with chikungunya fever., PMID:32565125
Galectin-3 mediates survival and apoptosis pathways during Trypanosoma cruzi-host cell interplay., PMID:32535113
Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity., PMID:32501939
Development of a Chimeric Antigen-Binding Fragment Directed Against Human Galectin-3 and Validation as an Immuno-Positron Emission Tomography Tracer for the Sensitive In Vivo Imaging of Thyroid Cancer., PMID:32200708
For research use only. Not for human or drug use.
