Catalog No.
RWN27401
Species reactivity
Crotalus durissus terrificus (South American rattlesnake), Crotalus scutulatus scutulatus (Mojave rattlesnake)
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Target
Phospholipase A2 crotoxin basic subunit CBc, CB1, CTX subunit CBc, svPLA2, 3.1.1.4, Phosphatidylcholine 2-acylhydrolase, Basic phospholipase A2 Mtx-b, svPLA2, 3.1.1.4, Mojave toxin basic chain, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 CB1, Crotalus durissus terrificus (South American rattlesnake), Crotalus scutulatus scutulatus (Mojave rattlesnake)
Concentration
1.51 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P62022, P62023
Applications
ELISA, FCM, IF, SPR, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Al0G
Effect of the phospholipase A2 inhibitor Varespladib, and its synergism with crotalic antivenom, on the neuromuscular blockade induced by Crotalus durissus terrificus venom (with and without crotamine) in mouse neuromuscular preparations., PMID:35580653
Expanding the neutralization scope of the Central American antivenom (PoliVal-ICP) to include the venom of Crotalus durissus pifanorum., PMID:34216808
Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine., PMID:28507562
First crotoxin-like phospholipase A(2) complex from a New World non-rattlesnake species: nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis., PMID:25434534
Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America., PMID:19863078
Expression of human recombinant antibody fragments capable of partially inhibiting the phospholypase activity of Crotalus durissus terrificus venom., PMID:19486333
Ability of rabbit antiserum against crotapotin to neutralize the neurotoxic, myotoxic and phospholipase A2 activities of crotoxin from Crotalus durissus cascavella snake venom., PMID:17920236
Rabbit IgG antibodies against phospholipase A2 from Crotalus durissus terrificus neutralize the lethal activity of the venom., PMID:17240621
Anti-sera raised in rabbits against crotoxin and phospholipase A2 from Crotalus durissus cascavella venom neutralize the neurotoxicity of the venom and crotoxin., PMID:15246761
Geographic and ontogenic variability in the venom of the neotropical rattlesnake Crotalus durissus: pathophysiological and therapeutic implications., PMID:12298262
Effect of heating on the toxic, immunogenic and immunosuppressive activities of Crotalus durissus terrificus venom., PMID:10758279
Neutralizing human anti crotoxin scFv isolated from a nonimmunized phage library., PMID:10736105
Neutralizing capacity of antisera raised in horses and rabbits against Crotalus durissus terrificus (South American rattlesnake) venom and its main toxin, crotoxin., PMID:10414861
A monoclonal antibody directed against the non-toxic subunit of a dimeric phospholipase A2 neurotoxin, crotoxin, neutralizes its toxicity., PMID:9705154
Biologically active human anti-crotoxin scFv isolated from a semi-synthetic phage library., PMID:9237096
Effect of Crotalus venom on the humoral and cellular immune response., PMID:9133715
Immunochemical analysis of a snake venom phospholipase A2 neurotoxin, crotoxin, with monoclonal antibodies., PMID:1378931
Purification and properties of an antivenom factor from the plasma of the South American rattlesnake (Crotalus durissus terrificus)., PMID:1949070
Protection against the lethal effects of Crotalus durissus terrificus (South American rattlesnake) venom in animals immunized with crotoxin., PMID:2128567
Neutralization of lethal potency and inhibition of enzymatic activity of a phospholipase A2 neurotoxin, crotoxin, by non-precipitating antibodies (Fab)., PMID:2466692
Crotoxin, half-century of investigations on a phospholipase A2 neurotoxin., PMID:2562459
Specificity of antibodies to the reconstituted crotoxin complex, from the venom of South American rattlesnake (Crotalus durissus terrificus), using enzyme-linked immunosorbent assay (ELISA) and double immunodiffusion., PMID:6784278
Sites of action of Mojave toxin isolated from the venom of the Mojave rattlesnake., PMID:7397452
For research use only. Not for human or drug use.
