Catalog No.
VHJ62501
Species reactivity
Human
Isotype
BiTE-bispecific antibody
Clonality
Monoclonal
Target
TREM1, Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1, TREM-1, CD354, Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
Q9NP99 & P15529
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2036
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization., PMID:40501642
The HL-60 clone 15 cell line as a model for leukocyte migration-possibilities and limitations., PMID:40496865
CD46 TREM1 regulates the autophagy marker LC3B ATG5 in oral squamous cell carcinoma., PMID:40475017
Soluble triggering receptor expressed on myeloid cells 1 is associated with hemoconcentration and endothelial activation in children and young adults with dengue virus infection in the Philippines., PMID:40455726
TREM-1-Linked Inflammatory Cargo in SARS-CoV-2-Stimulated Macrophage Extracellular Vesicles Drives Cellular Senescence and Impairs Antibacterial Defense., PMID:40431622
Endothelial TREM-1 mediates sepsis-induced blood‒brain barrier disruption and cognitive impairment via the PI3K/Akt pathway., PMID:40426195
[68Ga]Ga-NOTA-C-IPB-AIT: A novel radiotracer for in vivo detection of TREM-1 expression., PMID:40403496
Metabolism-associated marker gene-based predictive model for prognosis, targeted therapy, and immune landscape in ovarian cancer: an integrative analysis of single-cell and bulk RNA sequencing with spatial transcriptomics., PMID:40382612
Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis., PMID:40373963
Shortened PGLYRP1 Peptides Regulate Antitumor Activity of Cytotoxic Lymphocytes via TREM-1 Receptor: From Biology to Bioinformatics., PMID:40362307
Identification and Exploration of Pyroptosis-Related Genes in Macrophage Cells Reveal Necrotizing Enterocolitis Heterogeneity Through Single-Cell and Bulk-Sequencing., PMID:40362275
Integrative Analysis Reveals Genes Causal Relation with Ovarian Cancer and aging., PMID:40353459
A mechanism-based prognostic enrichment strategy for the development of the TREM-1 inhibitor nangibotide in septic shock., PMID:40323456
Targeting TREM-1 receptors with metformin and pravastatin modulate monosodium iodoacetate-induced osteoarthritis., PMID:40319222
Soluble TREM-1 ameliorates gouty arthritis by selective inhibition of proinflammatory cytokines and chemokines without affecting TGFβ production., PMID:40314990
A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity., PMID:40305049
Inflammatory markers in prostate cancer: potential roles in risk stratification and immune profiling., PMID:40296239
Biomarkers in Aneurysmatic and Spontaneous Subarachnoid Haemorrhage: A Clinical Prospective Multicentre Biomarker Panel Study of S100B, Claudin-5, Interleukin-10, TREM-1, TREM-2 and Neurofilament Light Chain As Well As Immunoglobulin G and M., PMID:40295361
JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection., PMID:40253010
Differential immunoregulation by human surfactant protein A variants determines severity of SARS-CoV-2-induced lung disease., PMID:40242753
Blocking triggering receptors expressed on myeloid cell-1 alleviates alveolar epithelial cell senescence by inhibiting oxidative stress in pulmonary fibrosis., PMID:40240638
Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques., PMID:40211055
Soluble Triggering Receptors on Myeloid Cells-1 Could Be a Potential Biomarker for Disease Activity in Familial Mediterranean Fever., PMID:40183453
Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy., PMID:40181552
Transcriptome Analysis of Monocytes Treated with Dengue NS1 Revealed a Shift in Transcripts Involving in Self-Propagated Proinflammation and Antiviral Responses., PMID:40166903
A Perceived Dissociation Between Systemic Chronic Inflammation, Age, and the Telomere/Telomerase System in Type 2 Diabetes., PMID:40149509
Role of triggering receptor expressed on myeloid cells 1/2 in secondary injury after cerebral hemorrhage., PMID:40144485
Age-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis., PMID:40126543
Diagnostic value of sTREM-1, sCD25, sCD40L and sCD130 in late-onset neonatal sepsis., PMID:40118381
Correction: The properties of TREM1 and its emerging role in pain-related diseases., PMID:40114216
Surface triggering receptor expressed on myeloid cells-1 (sTREM1) in critically ill children: a prospective observational controlled study., PMID:40084728
Myeloid targeting antibodies PY159 and PY314 for platinum-resistant ovarian cancer., PMID:40081941
The role of the TREM receptor family in cardiovascular diseases: Functions, mechanisms, and therapeutic target., PMID:40068732
Whole genome transcriptomic profiling reveals distinct sex-specific responses to heat stroke., PMID:40066897
HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB., PMID:40057252
Uncovering the role of TREM-1 in celiac disease: In silico insights into the recognition of gluten-derived peptides and inflammatory mechanisms., PMID:40056844
Tissue-resident CCR2+ macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts., PMID:40042972
Predicting interactome networks of up/down regulated proteins and drug-gene interaction analysis associated with peri-implantitis., PMID:40028501
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1., PMID:40014188
The properties of TREM1 and its emerging role in pain-related diseases., PMID:40011963
A Panel of Diverse Inflammatory Biomarkers Is Not Associated with BMI-Calibrated Obesity nor with Dyslipidemia or Dysglycemia in Clinically Healthy Adults Aged 20 to 40 Years., PMID:40003433
Downstream Link of Vitamin D Pathway with Inflammation Irrespective of Plasma 25OHD3: Hints from Vitamin D-Binding Protein (DBP) and Receptor (VDR) Gene Polymorphisms., PMID:40002798
Gut-derived macrophages link intestinal damage to brain injury after cardiac arrest through TREM1 signaling., PMID:39984674
TREM-1 as a Potential Coreceptor in Norovirus Pathogenesis: Insights from Transcriptomic Analysis and Molecular Docking., PMID:39959083
SaaS sRNA promotes the interfering effect of Salmonella on hepatic iron metabolism via modulating ferroportin 1., PMID:39935453
CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study., PMID:39897524
Association of CSF soluble TREM1 levels with hippocampal atrophy in cognitively impaired older adults., PMID:39877076
Urine proteomics defines an immune checkpoint-associated nephritis signature., PMID:39863302
Potentials of Presepsin as a Novel Sepsis Biomarker in Critically Ill Adults: Correlation Analysis with the Current Diagnostic Markers., PMID:39857101
Transcription factor Yy1 modulates Trem1 to control LPS-triggered neuroinflammation and oxidative stress in mouse astrocytes via the NF-κB pathway., PMID:39815902
For research use only. Not for human or drug use.
