Anti-Kv1.1 K+ channel Antibody (K20/78)

Catalog No.

RHG20601

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Voltage-gated K(+) channel HuKI, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage-gated channel subfamily A member 1, KCNA1, Voltage-gated potassium channel HBK1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

K20/78

LGI1 Autoantibodies Enhance Synaptic Transmission by Presynaptic Kv1 Loss and Increased Action Potential Broadening., PMID:39141878

Kv1.1 channels inhibition in the rat motor cortex recapitulates seizures associated with anti-LGI1 encephalitis., PMID:35283238

Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following pilocarpine-induced status epilepticus., PMID:33393091

ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents., PMID:30965109

3D multiplexed immunoplasmonics microscopy., PMID:27336475

Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway., PMID:26611796

Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephron., PMID:24948003

The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker., PMID:22558454

Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain., PMID:22473424

Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome., PMID:21088294

Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor., PMID:20557422

Voltage-gated delayed rectifier K v 1-subunits may serve as distinctive markers for enteroglial cells with different phenotypes in the murine ileum., PMID:19549557

Voltage-gated potassium channel (Kv) subunits expressed in the rat cochlear nucleus., PMID:18256021

Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus., PMID:17869444

Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K., PMID:17185748

Neuromyotonia and limbic encephalitis sera target mature Shaker-type K+ channels: subunit specificity correlates with clinical manifestations., PMID:16613892

Quantitative analysis of voltage-gated potassium currents from primary equine (Equus caballus) and elephant (Loxodonta africana) articular chondrocytes., PMID:15802557

Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter., PMID:15618540

Identification of a Kv3.4 channel in corneal epithelial cells., PMID:15161842

A voltage-gated K(+) current in renal inner medullary collecting duct cells., PMID:14684382

Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells., PMID:14602579

Adult alveolar epithelial cells express multiple subtypes of voltage-gated K+ channels that are located in apical membrane., PMID:12606310

Expression of KCNA10, a voltage-gated K channel, in glomerular endothelium and at the apical membrane of the renal proximal tubule., PMID:12444201

Identification of distinct K+ channels in mouse spermatogenic cells and sperm., PMID:12056459

Potassium channel KV alpha1 subunit expression and function in human detrusor muscle., PMID:11912453

Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2)., PMID:11825900

Distinct potassium channels on pain-sensing neurons., PMID:11698689

K(V)alpha1 channels in murine arterioles: differential cellular expression and regulation of diameter., PMID:11514271

Immunohistochemical study on the distribution of six members of the Kv1 channel subunits in the rat cerebellum., PMID:11259775

KV1.1 K(+) channels identification in human breast carcinoma cells: involvement in cell proliferation., PMID:11097830

Subunit composition and novel localization of K+ channels in spinal cord., PMID:11086297

Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation., PMID:10849663

KChAP as a chaperone for specific K(+) channels., PMID:10794667

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve., PMID:10739574

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels., PMID:10624965

Recreation of neuronal Kv1 channel oligomers by expression in mammalian cells using Semliki Forest virus., PMID:10606508

Potassium current suppression in patients with peripheral nerve hyperexcitability., PMID:10545391

Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors., PMID:10528121

Subunit composition of Kv1 channels in human CNS., PMID:10428084

Memory and long-term potentiation (LTP) dissociated: normal spatial memory despite CA1 LTP elimination with Kv1.4 antisense., PMID:9844011

Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes., PMID:9616203

Differential distribution of Shaker-like and Shab-like K+-channel subunits in goldfish retina and retinal bipolar cells., PMID:9623892

Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, a novel peptide derived from Centruroides limbatus venom., PMID:9446567

Complex subunit assembly of neuronal voltage-gated K+ channels. Basis for high-affinity toxin interactions and pharmacology., PMID:9346893

Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes., PMID:9334400

Generation and characterization of subtype-specific monoclonal antibodies to K+ channel alpha- and beta-subunit polypeptides., PMID:8938716

Antibodies specific for distinct Kv subunits unveil a heterooligomeric basis for subtypes of alpha-dendrotoxin-sensitive K+ channels in bovine brain., PMID:8110763

Application of an ectopic expression system for the selection of protein-isoform-specific antibodies. The monoclonal antibody K1C3 is specific for the RCK1 potassium channel., PMID:8404907

Immunological Identification of the Shaker-Related Kv1.3 Potassium Channel Protein in T and B Lymphocytes, and Detection of Related Proteins in Flies and Yeast., PMID:8447822

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