Anti-cleaved MMP-9 Antibody (L103/15)

Catalog No.

RHD06803

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

L103/15

Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S., PMID:39000375

The TGF-β/MMP9/RAGE axis induces sRAGE secretion by neutrophils and promotes oral carcinogenesis., PMID:38463640

Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S., PMID:38318187

MMP9-Responsive Graphene Oxide Quantum Dot-Based Nano-in-Micro Drug Delivery System for Combinatorial Therapy of Choroidal Neovascularization., PMID:36871144

Randomized, open-label, phase 2 study of andecaliximab plus nivolumab versus nivolumab alone in advanced gastric cancer identifies biomarkers associated with survival., PMID:34893523

Cascade-Responsive Hierarchical Nanosystems for Multisite Specific Drug Exposure and Boosted Chemoimmunotherapy., PMID:34855343

Functional selection of protease inhibitory antibodies., PMID:31363054

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus., PMID:30967870

Effects of Granulocyte-Macrophage Colony-Stimulating Factor on Neuronal Senescence in Ultraviolet Irradiated Skin., PMID:30807472

Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes., PMID:30786281

A role of PSA-NCAM in the survival of retinal ganglion cells (RGCs) after kainic acid damage., PMID:30772382

Matrix Metalloproteinase-2 and -9 Expression in the Epiligament of the Medial Collateral and Anterior Cruciate Ligament in Human Knees: A Comparative Study., PMID:30648082

MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors., PMID:30500835

Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice., PMID:30262472

Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality., PMID:30169632

Endotoxin-induced changes of type VII collagen- cleaving matrix metalloproteinases in lamellar tissue of extracorporeally perfused equine limbs., PMID:30153058

MMP-9-cleaved osteopontin isoform mediates tumor immune escape by inducing expansion of myeloid-derived suppressor cells., PMID:28986261

PAR-1 and PAR-2 Expression Is Enhanced in Inflamed Odontoblast Cells., PMID:28759300

Effects of C-reactive protein on the expression of matrix metalloproteinases and their inhibitors via Fcγ receptors on 3T3-L1 adipocytes., PMID:28539825

Nuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain., PMID:28533891

M2 macrophages induce ovarian cancer cell proliferation via a heparin binding epidermal growth factor/matrix metalloproteinase 9 intercellular feedback loop., PMID:27888810

Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis., PMID:27542125

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage., PMID:27141350

Hsa-miR-326 targets CCND1 and inhibits non-small cell lung cancer development., PMID:26840018

Inhibition of tumor progression by oral piceatannol in mouse 4T1 mammary cancer is associated with decreased angiogenesis and macrophage infiltration., PMID:26297476

Dysfunctional Antibodies in the Tumor Microenvironment Associate with Impaired Anticancer Immunity., PMID:26224871

Immunological blockade of adipocyte inflammation caused by increased matrix metalloproteinase-cleaved osteopontin in obesity., PMID:25776538

WFDC1 is a key modulator of inflammatory and wound repair responses., PMID:25219356

Osthole exhibits anti-cancer property in rat glioma cells through inhibiting PI3K/Akt and MAPK signaling pathways., PMID:24356539

Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes., PMID:24283517

Pipoxolan ameliorates cerebral ischemia via inhibition of neuronal apoptosis and intimal hyperplasia through attenuation of VSMC migration and modulation of matrix metalloproteinase-2/9 and Ras/MEK/ERK signaling pathways., PMID:24086601

Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model., PMID:23625311

Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides., PMID:23624916

Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage., PMID:23358111

The N-terminal ectodomain of Ninjurin1 liberated by MMP9 has chemotactic activity., PMID:23142597

Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation., PMID:22818364

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis., PMID:22382088

Heparanase accelerates the proliferation of both hepatocytes and endothelial cells early after partial hepatectomy., PMID:22305926

Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid., PMID:21880713

Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice., PMID:21871134

Phenotypic expression of ADAMTS13 in glomerular endothelial cells., PMID:21720563

Matrix metalloprotease-9 induces transforming growth factor-β(1) production in airway epithelium via activation of epidermal growth factor receptors., PMID:21718706

Constitutive expression and enzymatic cleavage of ICAM-1 in the spontaneously hypertensive rat., PMID:21464573

Trafficking and secretion of matrix metalloproteinase-2 in olfactory ensheathing glial cells: A role in cell migration?, PMID:21360755

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein., PMID:21055468

CD10-bearing fibroblast inhibits matrigel invasive potency of interleukin-1α-producing squamous cell carcinoma by diminishing substance P levels in the tumor microenvironment., PMID:20874839

Matrix metalloproteinase-9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion., PMID:20699364

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen., PMID:20380828

Tranilast inhibits cell proliferation and migration and promotes apoptosis in murine breast cancer., PMID:20145538

TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23., PMID:19635918

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