Catalog No.
YHC35902
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile213-Pro466
Predicted molecular weight
30.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08709
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
F7, Proconvertin, SPCA, Serum prothrombin conversion accelerator, Coagulation factor VII, Eptacog alfa
Identification and evaluation of Pharmacological enhancers of the factor VII p.Q160R variant., PMID:40274887
A novel compound heterozygous mutation (c.64G > A and c.506-1G > A) associated with congenital coagulation factor VII deficiency: a case report and literature review., PMID:40257480
Analysis of clinical manifestations and molecular pathogenesis of six patients with hereditary blood coagulation factor VII deficiency., PMID:40117674
Frequency and Association of Polymorphisms in F2, F7, and PROS1 Coagulation Genes with Disease Severity in Coronavirus Disease 2019., PMID:39497411
Macrophage-Expressed Coagulation Factor VII Promotes Adverse Cardiac Remodeling., PMID:39234697
Clinical, Laboratory, and Molecular Aspects of Factor VII Deficiency., PMID:39209290
Hereditary coagulation factor VII deficiency caused by novel compound heterozygous mutations c.572-1G>A and c.1037A>C in a Chinese pedigree., PMID:39047958
Synonymous variant at the terminal nucleotide in exon 3 of F7 causes abnormal splicing: A case report., PMID:39007454
[Congenital FⅦ Deficiency Associated with a Novel Mutation in F7 Gene]., PMID:38926980
Inherited coagulation factor VII deficiency in Taiwan: Two novel F7 variants with relevant regional features in 33 patients., PMID:38783550
Network pharmacology analysis and experimental verification of the antithrombotic active compounds of trichosanthis pericarpium (Gualoupi) in treating coronary heart disease., PMID:38614263
[Analysis of three Chinese pedigrees affected with Hereditary factor Ⅶ deficiency due to compound heterozygous variants of F7 gene]., PMID:38565502
The identification of a novel compound heterozygous mutation in hereditary human coagulation factor VII deficiency following a bamboo leaf green snake bite., PMID:38447534
Genetic Landscape of Factor VII Deficiency: Insights from a Comprehensive Analysis of Pathogenic Variants and Their Impact on Coagulation Activity., PMID:38397060
Coagulation Factor VII Fine-tunes Hepatic Steatosis by Blocking AKT-CD36-Mediated Fatty Acid Uptake., PMID:38394642
Frequency of the p.Thr241Asn mutation in Chinese patients with congenital factor VII deficiency., PMID:38335567
Patient with congenital factor VII deficiency undergoing brain tumor neurosurgery successfully treated with recombinant factor VIIa and fresh frozen plasma: A case report and literature review., PMID:38206717
Molecular Genetic Analysis of Russian Patients with Coagulation Factor FVII Deficiency., PMID:37761907
Knockdown of coagulation factor VII has potential anticoagulant and anti-inflammatory effects in a mouse model of group A streptococcal sepsis., PMID:37392986
A case-report of the unprovoked thrombotic event in a patient with thymoma and severe FVII deficiency., PMID:37143073
Factor VII deficiency: A cause of (or risk factor for) bleeding?, PMID:37042485
Structural and functional characterization of novel F7 mutations identified in Chinese factor VII-deficient patients., PMID:36951360
Factor VII Padua in Iran: clinical and laboratory findings of three unrelated patients., PMID:36719811
Hereditary coagulation factor VII deficiency caused by novel compound heterozygous mutations in a Chinese pedigree: A case report., PMID:36572978
Molecular spectrum of inherited FVII deficiency in North India revealed a recurrent variant with a founder effect., PMID:36571800
Factor VII deficiency in China: Phenotype, genotype and current status of management., PMID:36229963
Factor VII Deficiency Due to Compound Heterozygosity for the p.Leu13Pro Mutation and a Novel Mutation in the HNF4 Binding Region (-58G>C) in the F7 Promoter., PMID:36123027
Mutations of TFPI-binding exosites on factor VII cause bleeding phenotypes in factor VII deficiency., PMID:35973191
Investigation of a common canine factor VII deficiency variant in dogs with unexplained bleeding on autopsy., PMID:35949113
Phenotypic and genotypic characterization of two factor VII deficiency patients from southeastern China., PMID:35867939
Clinical phenotype and F7 gene genotype in 40 Tunisian patients with congenital factor VII deficiency., PMID:35802509
Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes., PMID:35588731
Whole-exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors., PMID:35552711
Novel heterozygous F7 gene mutation (c. C1286T) associated with congenital factor VII deficiency: A case report and literature review., PMID:35349734
Human transcriptomic response to periprosthetic joint infection., PMID:35306116
A novel compound heterozygous variant linked to hematuria in a family with hereditary factor VII deficiency., PMID:34786791
Polymorphisms of F2 (G20210A), F5 (G1691A), F 7 (G10976A), F 13(G13T), FGB, ITGA2, ITGB3, PAI-I genes and its association with thrombotic complications in patients suffering from Takayasu aortoarteritis of Urals population., PMID:34523592
Novel factor VII gene mutations in six families with hereditary coagulation factor VII deficiency., PMID:34342048
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding., PMID:33742435
Identification of two novel mutations in three children with congenital factor VII deficiency., PMID:33587484
Compound Heterozygous Mutations in the F7 Gene in 2 Unrelated Families With Congenital Factor VII Deficiency., PMID:33480651
Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis., PMID:33406812
Generation of a human induced pluripotent stem cell line, YCMi002-A, from a Factor VII deficiency patient carrying F7 mutations., PMID:33038747
Determining the association of thrombophilic gene polymorphisms with recurrent pregnancy loss in Iranian women., PMID:32496885
[Analysis of a Chinese pedigree affected with hereditary factor VII deficiency caused by compound heterozygous variants of F7 gene]., PMID:32472540
The EAHAD blood coagulation factor VII variant database., PMID:32333443
Variations of circulating miRNA in paediatric patients with Heart Failure supported with Ventricular Assist Device: a pilot study., PMID:32246041
Aptamer-modified FXa generation assays to investigate hypercoagulability in plasma from patients with ischemic heart disease., PMID:32224381
17β-Estradiol and the glucocorticoid clobetasol propionate affect the blood coagulation cascade in zebrafish., PMID:31887585
Analysis of Phenotype and Genotypein an Inherited Coagulation Factor VII Deficiency Pedigree., PMID:31850724
For research use only. Not for human or drug use.
