Catalog No.
PMK97801
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse RGMB (Gly156-Arg404).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)
Purification
Purified by antigen affinity column.
Accession
Q7TQ33
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting RGMb interactions: Discovery and preclinical characterization of potent anti-RGMb antibodies blocking multiple ligand bindings., PMID:39588913
The B7:CD28 family and friends: Unraveling coinhibitory interactions., PMID:38354702
Regulatory role of RGMb in lung injury promoted by the combination of carbon ion irradiation and anti-PD-1 antibody through Erk1/2 and p38 MAPK pathways., PMID:38042034
Microbiota-associated immunotherapy resistance caused by deficient PD-L2 - RGMb signaling., PMID:37396957
Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance., PMID:37138075
Immunoregulatory effects of RGMb in gut inflammation., PMID:36420263
An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy., PMID:35924382
RGMB enhances the suppressive activity of the monomeric secreted form of CTLA-4., PMID:31061392
Blockade of RGMb inhibits allergen-induced airways disease., PMID:30703386
Growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor α1 (Gfrα1), two mouse oocyte glycosylphosphatidylinositol-anchored proteins, are involved in fertilisation., PMID:28442042
Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity., PMID:17568789
For research use only. Not for human or drug use.
