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Anti-Mouse CD321/F11R Polyclonal Antibody

Catalog #:   PMJ90501 Specific References (97) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O88792
Overview

Catalog No.

PMJ90501

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD321/F11R (Gly53-Glu233).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321)

Purification

Purified by antigen affinity column.

Accession

O88792

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with F11R antibody (PMJ90501) at 1 µg/ml.

    Lane 1: Mouse lung lysate
    Lane 2: Rat lung lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 32 kDa
    Observed MW: 38 kDa
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD321/F11R antibody (PMJ90501) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 22 kDa
    Observed MW: 22 kDa
References

Multilayered proteomics reveals that JAM-A promotes breast cancer progression via regulation of amino acid transporter LAT1., PMID:38943512

Multilayered proteomics reveals that JAM-A promotes breast cancer progression via regulation of amino acid transporter LAT1., PMID:38943512

Targeting the tetraspanin CD81 reduces cancer invasion and metastasis., PMID:34099563

Targeting the tetraspanin CD81 reduces cancer invasion and metastasis., PMID:34099563

Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury., PMID:33737554

Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury., PMID:33737554

Aberrant expression of junctional adhesion molecule-A contributes to the malignancy of cervical adenocarcinoma by interaction with poliovirus receptor/CD155., PMID:33185939

Aberrant expression of junctional adhesion molecule-A contributes to the malignancy of cervical adenocarcinoma by interaction with poliovirus receptor/CD155., PMID:33185939

Generation of Genetically RGD σ1-Modified Oncolytic Reovirus That Enhances JAM-A-Independent Infection of Tumor Cells., PMID:32907973

Generation of Genetically RGD σ1-Modified Oncolytic Reovirus That Enhances JAM-A-Independent Infection of Tumor Cells., PMID:32907973

Mechanisms of CNS Viral Seeding by HIV+ CD14+ CD16+ Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders., PMID:29066542

Mechanisms of CNS Viral Seeding by HIV+ CD14+ CD16+ Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders., PMID:29066542

Patients with a new variant of endemic pemphigus foliaceus have autoantibodies against arrector pili muscle, colocalizing with MYZAP, p0071, desmoplakins 1 and 2 and ARVCF., PMID:29034528

Patients with a new variant of endemic pemphigus foliaceus have autoantibodies against arrector pili muscle, colocalizing with MYZAP, p0071, desmoplakins 1 and 2 and ARVCF., PMID:29034528

A novel immunotoxin reveals a new role for CD321 in endothelial cells., PMID:29028806

A novel immunotoxin reveals a new role for CD321 in endothelial cells., PMID:29028806

EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion Through Junctional Adhesion Molecule A in Lupus Patients., PMID:28973837

EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion Through Junctional Adhesion Molecule A in Lupus Patients., PMID:28973837

Epitope characterization of anti-JAM-A antibodies using orthogonal mass spectrometry and surface plasmon resonance approaches., PMID:28933642

Epitope characterization of anti-JAM-A antibodies using orthogonal mass spectrometry and surface plasmon resonance approaches., PMID:28933642

Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma., PMID:28837251

Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma., PMID:28837251

Expression and prognostic value of JAM-A in gliomas., PMID:28677106

Expression and prognostic value of JAM-A in gliomas., PMID:28677106

Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells., PMID:28196955

Identification of Human Junctional Adhesion Molecule 1 as a Functional Receptor for the Hom-1 Calicivirus on Human Cells., PMID:28196955

Analysis of the expression and localization of tight junction transmembrane proteins, claudin-1, -4, -7, occludin and JAM-A, in human cervical adenocarcinoma., PMID:26847087

Analysis of the expression and localization of tight junction transmembrane proteins, claudin-1, -4, -7, occludin and JAM-A, in human cervical adenocarcinoma., PMID:26847087

Urinary trypsin inhibitor attenuates LPS-induced endothelial barrier dysfunction by upregulation of vascular endothelial-cadherin expression., PMID:26681130

Urinary trypsin inhibitor attenuates LPS-induced endothelial barrier dysfunction by upregulation of vascular endothelial-cadherin expression., PMID:26681130

F11R mRNA expression and promoter polymorphisms in patients with rheumatoid arthritis., PMID:26230081

F11R mRNA expression and promoter polymorphisms in patients with rheumatoid arthritis., PMID:26230081

Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer., PMID:25916097

Junctional adhesion molecule-A promotes proliferation and inhibits apoptosis of gastric cancer., PMID:25916097

JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals., PMID:25420915

JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals., PMID:25420915

Junctional adhesion molecule-A, an epithelial-mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancer., PMID:25416560

A phase I trial of single-agent reolysin in patients with relapsed multiple myeloma., PMID:25294913

Junctional adhesion molecule-A, an epithelial-mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancer., PMID:25416560

Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution., PMID:24704627

Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution., PMID:24704627

Digestion of epithelial tight junction proteins by the commensal Clostridium perfringens., PMID:24072681

Mechanisms of HIV entry into the CNS: increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in diapedesis., PMID:23922698

Mechanisms of HIV entry into the CNS: increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in diapedesis., PMID:23922698

House dust mite allergen Der p 1 effects on sinonasal epithelial tight junctions., PMID:23592402

House dust mite allergen Der p 1 effects on sinonasal epithelial tight junctions., PMID:23592402

Integrity of the blood-testis barrier in healthy men after suppression of spermatogenesis with testosterone and levonorgestrel., PMID:23019303

Integrity of the blood-testis barrier in healthy men after suppression of spermatogenesis with testosterone and levonorgestrel., PMID:23019303

A method for short-term culture of human gastric epithelial cells to study the effects of Helicobacter pylori., PMID:23015492

A method for short-term culture of human gastric epithelial cells to study the effects of Helicobacter pylori., PMID:23015492

A novel role for junctional adhesion molecule-A in tumor proliferation: modulation by an anti-JAM-A monoclonal antibody., PMID:22886345

A novel role for junctional adhesion molecule-A in tumor proliferation: modulation by an anti-JAM-A monoclonal antibody., PMID:22886345

Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection., PMID:22811534

Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection., PMID:22811534

Ligation of CD24 expressed by oral epithelial cells induces kinase dependent decrease in paracellular permeability mediated by tight junction proteins., PMID:21806966

Ligation of CD24 expressed by oral epithelial cells induces kinase dependent decrease in paracellular permeability mediated by tight junction proteins., PMID:21806966

Cardiac autoantibodies from patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America., PMID:21796504

Cardiac autoantibodies from patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America., PMID:21796504

Association between adherens junctions and tight junctions via Rap1 promotes barrier protective effects of oxidized phospholipids., PMID:21520057

Association between adherens junctions and tight junctions via Rap1 promotes barrier protective effects of oxidized phospholipids., PMID:21520057

Junctional adhesion molecules are required for melanoma cell lines transendothelial migration in vitro., PMID:21466663

Junctional adhesion molecules are required for melanoma cell lines transendothelial migration in vitro., PMID:21466663

Tight junctions in cancer metastasis., PMID:21196209

Tight junctions in cancer metastasis., PMID:21196209

Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells., PMID:20932985

miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness., PMID:20818426

miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness., PMID:20818426

Silencing of the F11R gene reveals a role for F11R/JAM-A in the migration of inflamed vascular smooth muscle cells and in atherosclerosis., PMID:20627246

Silencing of the F11R gene reveals a role for F11R/JAM-A in the migration of inflamed vascular smooth muscle cells and in atherosclerosis., PMID:20627246

Junctional adhesion molecule-C is a soluble mediator of angiogenesis., PMID:20592283

Junctional adhesion molecule-C is a soluble mediator of angiogenesis., PMID:20592283

Role of calcium signalling and phosphorylations in disruption of the epithelial junctions by Pseudomonas aeruginosa quorum sensing molecule., PMID:20434232

Role of calcium signalling and phosphorylations in disruption of the epithelial junctions by Pseudomonas aeruginosa quorum sensing molecule., PMID:20434232

From touchdown to transcription: the reovirus cell entry pathway., PMID:20397070

From touchdown to transcription: the reovirus cell entry pathway., PMID:20397070

Junctional adhesion molecule A expressed on human CD34+ cells promotes adhesion on vascular wall and differentiation into endothelial progenitor cells., PMID:20378847

Junctional adhesion molecule A expressed on human CD34+ cells promotes adhesion on vascular wall and differentiation into endothelial progenitor cells., PMID:20378847

Investigation of the binding preference of reovirus sigma1 for junctional adhesion molecule A by classical and steered molecular dynamics., PMID:20102214

Investigation of the binding preference of reovirus sigma1 for junctional adhesion molecule A by classical and steered molecular dynamics., PMID:20102214

Induction of JAM-A during differentiation of human THP-1 dendritic cells., PMID:19748485

Induction of JAM-A during differentiation of human THP-1 dendritic cells., PMID:19748485

Extending mass spectrometry contribution to therapeutic monoclonal antibody lead optimization: characterization of immune complexes using noncovalent ESI-MS., PMID:19588976

Extending mass spectrometry contribution to therapeutic monoclonal antibody lead optimization: characterization of immune complexes using noncovalent ESI-MS., PMID:19588976

The role of JAM-A in inflammatory bowel disease: unrevealing the ties that bind., PMID:19538321

The role of JAM-A in inflammatory bowel disease: unrevealing the ties that bind., PMID:19538321

Mechanisms of outside-in signaling at the tight junction by junctional adhesion molecule A., PMID:19538282

Mechanisms of outside-in signaling at the tight junction by junctional adhesion molecule A., PMID:19538282

JAM-A expression positively correlates with poor prognosis in breast cancer patients., PMID:19533747

JAM-A expression positively correlates with poor prognosis in breast cancer patients., PMID:19533747

Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells., PMID:19433574

Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells., PMID:19433574

Junctional adhesion molecule A [corrected] expression in human endometrial carcinoma., PMID:19395995

Junctional adhesion molecule A [corrected] expression in human endometrial carcinoma., PMID:19395995

Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases., PMID:19258599

Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases., PMID:19258599

Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma., PMID:19250634

Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma., PMID:19250634

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-Mouse CD321/F11R Polyclonal Antibody [PMJ90501]
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