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Anti-Mouse IL34 Polyclonal Antibody

Catalog #:   PMJ10801 Specific References (93) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q8R1R4
Overview

Catalog No.

PMJ10801

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL34 (Asn21-Pro235).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Interleukin-34 (IL-34)

Purification

Purified by antigen affinity column.

Accession

Q8R1R4

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL34 antibody (PMJ10801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 27 kDa
    Observed MW: 27 kDa
References

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study., PMID:40381116

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study., PMID:40381116

New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804

New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804

Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal model., PMID:40016767

Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal model., PMID:40016767

Development of antigen-capture enzyme-linked immunoassay for Chicken Interleukin-34., PMID:39900196

Development of antigen-capture enzyme-linked immunoassay for Chicken Interleukin-34., PMID:39900196

Is there a relationship between CSF Interleukin 34 Level and clinicoradiological activity and IgG index in patients with MS?, PMID:39571220

Is there a relationship between CSF Interleukin 34 Level and clinicoradiological activity and IgG index in patients with MS?, PMID:39571220

AKAP12 positive fibroblast determines immunosuppressive contexture and immunotherapy response in patients with TNBC by promoting macrophage M2 polarization., PMID:39448199

AKAP12 positive fibroblast determines immunosuppressive contexture and immunotherapy response in patients with TNBC by promoting macrophage M2 polarization., PMID:39448199

Profiles of cytokines in patients with antineutrophil cytoplasmic antibody-associated vasculitis., PMID:39108259

Profiles of cytokines in patients with antineutrophil cytoplasmic antibody-associated vasculitis., PMID:39108259

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages., PMID:38844455

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages., PMID:38844455

Serum interleukin-34 levels in dermatomyositis: a potential biomarker for anti-MDA5-antibody-associated interstitial lung disease., PMID:38830088

Serum interleukin-34 levels in dermatomyositis: a potential biomarker for anti-MDA5-antibody-associated interstitial lung disease., PMID:38830088

CSF-1R in Cancer: More than a Myeloid Cell Receptor., PMID:38254773

CSF-1R in Cancer: More than a Myeloid Cell Receptor., PMID:38254773

Validation of CSF-1 receptor (CD115) staining for analysis of murine monocytes by flow cytometry., PMID:38038378

Validation of CSF-1 receptor (CD115) staining for analysis of murine monocytes by flow cytometry., PMID:38038378

Effects of IL-34 and anti-IL-34 neutralizing mAb on alveolar bone loss in a ligature-induced model of periodontitis., PMID:37902168

Effects of IL-34 and anti-IL-34 neutralizing mAb on alveolar bone loss in a ligature-induced model of periodontitis., PMID:37902168

Genetic and Immunohistochemistry Tools to Visualize Rat Macrophages In Situ., PMID:37639117

Genetic and Immunohistochemistry Tools to Visualize Rat Macrophages In Situ., PMID:37639117

Significance of IL-34 and SDC-1 in the pathogenesis of RA cells and preclinical models., PMID:37150238

Significance of IL-34 and SDC-1 in the pathogenesis of RA cells and preclinical models., PMID:37150238

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3., PMID:36252111

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3., PMID:36252111

Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer., PMID:36104597

Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer., PMID:36104597

IL-34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis., PMID:36030499

IL-34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis., PMID:36030499

CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation., PMID:35353625

CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation., PMID:35353625

Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation., PMID:35316296

Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation., PMID:35316296

Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodies against IgM of largemouth bass (Micropterus salmoides)., PMID:35314332

Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodies against IgM of largemouth bass (Micropterus salmoides)., PMID:35314332

Clinical evaluation of colony-stimulating factor 1 receptor inhibitors., PMID:34776301

Clinical evaluation of colony-stimulating factor 1 receptor inhibitors., PMID:34776301

[Interleukin-34: a key molecule in the tumor microenvironment]., PMID:34497220

[Interleukin-34: a key molecule in the tumor microenvironment]., PMID:34497220

An optimized protocol for patient-derived xenograft in humanized mice to evaluate the role of IL-34 in immunotherapeutic resistance., PMID:33899027

LY3022855, an anti-colony stimulating factor-1 receptor (CSF-1R) monoclonal antibody, in patients with advanced solid tumors refractory to standard therapy: phase 1 dose-escalation trial., PMID:33624233

LY3022855, an anti-colony stimulating factor-1 receptor (CSF-1R) monoclonal antibody, in patients with advanced solid tumors refractory to standard therapy: phase 1 dose-escalation trial., PMID:33624233

Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice., PMID:33428678

Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice., PMID:33428678

Interleukin-34 Limits the Therapeutic Effects of Immune Checkpoint Blockade., PMID:33205010

Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration., PMID:33162994

Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration., PMID:33162994

Impact of IL-34, IFN-α and IFN-λ1 on activity of systemic lupus erythematosus in Egyptian patients., PMID:32921829

Impact of IL-34, IFN-α and IFN-λ1 on activity of systemic lupus erythematosus in Egyptian patients., PMID:32921829

The M-CSF receptor in osteoclasts and beyond., PMID:32801364

C-reactive protein at 1 month after treatment of nivolumab as a predictive marker of efficacy in advanced renal cell carcinoma., PMID:32537714

C-reactive protein at 1 month after treatment of nivolumab as a predictive marker of efficacy in advanced renal cell carcinoma., PMID:32537714

Interleukin-34 as a marker for subclinical proliferative lupus nephritis., PMID:32237962

Interleukin 34 Serves as a Novel Molecular Adjuvant against Nocardia Seriolae Infection in Largemouth Bass (Micropterus Salmoides)., PMID:32231137

Interleukin 34 Serves as a Novel Molecular Adjuvant against Nocardia Seriolae Infection in Largemouth Bass (Micropterus Salmoides)., PMID:32231137

Elevated serum interleukin-34 level in juvenile systemic lupus erythematosus and disease activity., PMID:31907692

Elevated serum interleukin-34 level in juvenile systemic lupus erythematosus and disease activity., PMID:31907692

Interleukin-34 expression in ovarian cancer: a possible correlation with disease progression., PMID:31868884

Interleukin-34 expression in ovarian cancer: a possible correlation with disease progression., PMID:31868884

Serum levels of interleukin-34 and clinical correlation in patients with primary Sjögren's syndrome., PMID:31823505

Prognostic value of IL-34 in colorectal cancer patients., PMID:31762401

Prognostic value of IL-34 in colorectal cancer patients., PMID:31762401

Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling., PMID:31727934

Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling., PMID:31727934

Protective effects of seaweed supplemented diet on antioxidant and immune responses in European seabass (Dicentrarchus labrax) subjected to bacterial infection., PMID:31695116

Protective effects of seaweed supplemented diet on antioxidant and immune responses in European seabass (Dicentrarchus labrax) subjected to bacterial infection., PMID:31695116

CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions., PMID:31616414

CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions., PMID:31616414

Effect of Interleukin-34 on Secretion of Angiogenesis Cytokines by Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis., PMID:31401905

Effect of Interleukin-34 on Secretion of Angiogenesis Cytokines by Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis., PMID:31401905

Interleukin-34 as a promising clinical biomarker and therapeutic target for inflammatory arthritis., PMID:31126875

Interleukin-34 as a promising clinical biomarker and therapeutic target for inflammatory arthritis., PMID:31126875

A role for IL-34 in osteolytic disease of multiple myeloma., PMID:30782613

IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice., PMID:30622154

IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice., PMID:30622154

Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells., PMID:30573681

Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells., PMID:30573681

Interleukin 30 to Interleukin 40., PMID:30328794

Interleukin 30 to Interleukin 40., PMID:30328794

Histone deacetylase 6 regulated expression of IL-8 is involved in the doxorubicin (Dox) resistance of osteosarcoma cells via modulating ABCB1 transcription., PMID:30273544

Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study., PMID:30059939

Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study., PMID:30059939

Interleukin-34 Aggravates the Severity of Arthritis in Collagen-Induced Arthritis Mice by Inducing Interleukin-17 Production., PMID:29664689

Interleukin-34 Aggravates the Severity of Arthritis in Collagen-Induced Arthritis Mice by Inducing Interleukin-17 Production., PMID:29664689

Enhanced IL-34 expression in Nivolumab-resistant metastatic melanoma., PMID:29515691

Enhanced IL-34 expression in Nivolumab-resistant metastatic melanoma., PMID:29515691

Elevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity., PMID:29472590

Elevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity., PMID:29472590

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-Mouse IL34 Polyclonal Antibody [PMJ10801]
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