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Anti-Mouse IL27RA Polyclonal Antibody

Catalog #:   PMJ08601 Specific References (55) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O70394
Overview

Catalog No.

PMJ08601

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL27RA (Met121-Thr304).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Type I T-cell cytokine receptor) (TCCR) (WSX-1)

Purification

Purified by antigen affinity column.

Accession

O70394

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL27RA antibody (PMJ08601) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 23 kDa
    Observed MW: 23 kDa
References

Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia., PMID:38804310

Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma., PMID:36867577

Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma., PMID:36867577

IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis., PMID:35430461

IL-27 promotes decidualization via the STAT3-ESR/PGR regulatory axis., PMID:35430461

B cell-derived IL-27 promotes control of persistent LCMV infection., PMID:35022243

B cell-derived IL-27 promotes control of persistent LCMV infection., PMID:35022243

A prospective study revealing the role of an immune-related eRNA, WAKMAR2, in breast cancer., PMID:34321580

A prospective study revealing the role of an immune-related eRNA, WAKMAR2, in breast cancer., PMID:34321580

IL-27Rα: A Novel Molecular Imaging Marker for Allograft Rejection., PMID:32075272

IL-27Rα: A Novel Molecular Imaging Marker for Allograft Rejection., PMID:32075272

IL-27 Negatively Controls Antifungal Activity in a Model of Invasive Pulmonary Aspergillosis., PMID:31991091

IL-27 Negatively Controls Antifungal Activity in a Model of Invasive Pulmonary Aspergillosis., PMID:31991091

Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production., PMID:30127058

Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production., PMID:30127058

Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection., PMID:29593047

Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection., PMID:29593047

IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells., PMID:29020964

IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells., PMID:29020964

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3., PMID:25348624

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3., PMID:25348624

Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia., PMID:24408967

Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia., PMID:24408967

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39., PMID:23995234

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39., PMID:23995234

Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection., PMID:23993651

Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection., PMID:23993651

The composite cytokine p28/cytokine-like factor 1 sustains B cell proliferation and promotes plasma cell differentiation., PMID:23836062

The composite cytokine p28/cytokine-like factor 1 sustains B cell proliferation and promotes plasma cell differentiation., PMID:23836062

The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction., PMID:23165310

The emerging role of Interleukin 27 in inflammatory arthritis and bone destruction., PMID:23165310

Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice., PMID:22927332

Interleukin-27 receptor limits atherosclerosis in Ldlr-/- mice., PMID:22927332

TCCR/WSX-1 is a novel angiogenic factor in age-related macular degeneration., PMID:22312192

T cell-specific overexpression of interleukin-27 receptor α subunit (WSX-1) prevents spontaneous skin inflammation in MRL/lpr mice., PMID:21332454

T cell-specific overexpression of interleukin-27 receptor α subunit (WSX-1) prevents spontaneous skin inflammation in MRL/lpr mice., PMID:21332454

The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses., PMID:21281790

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells., PMID:21098093

The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses., PMID:21281790

Amelioration of experimental allergic rhinitis with suppression of topical immune responses by lack of IL-27/WSX-1 signaling., PMID:19354069

Amelioration of experimental allergic rhinitis with suppression of topical immune responses by lack of IL-27/WSX-1 signaling., PMID:19354069

Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses., PMID:19246719

Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses., PMID:19246719

IL-27 induces a Th1 immune response and susceptibility to experimental arthritis., PMID:18178832

Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)., PMID:18094002

Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1)., PMID:18094002

Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)., PMID:16301622

Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)., PMID:16301622

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice., PMID:16081811

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice., PMID:16081811

Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection., PMID:15067040

Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection., PMID:15067040

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27., PMID:14764690

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27., PMID:14764690

Development of Th1-type immune responses requires the type I cytokine receptor TCCR., PMID:11057672

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Mouse IL27RA Polyclonal Antibody [PMJ08601]
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