Catalog No.
PMJ05201
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse SFRP4 (Glu25-Asn116).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Secreted frizzled-related sequence protein 4 (FRP-4) (sFRP-4)
Purification
Purified by antigen affinity column.
Accession
Q9Z1N6
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Netrin-like domain of sFRP4, a Wnt antagonist inhibits stemness, metastatic and invasive properties by specifically blocking MMP-2 in cancer stem cells from human glioma cell line U87MG., PMID:34762897
Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options., PMID:30770859
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists., PMID:29129759
Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines., PMID:28536422
Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease., PMID:27355534
sFRP-4, a potential novel serum marker for chronic hepatitis B-related hepatocellular carcinoma., PMID:25865689
Genetic Approaches To Identifying Novel Osteoporosis Drug Targets., PMID:25833316
Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors., PMID:24217964
MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats., PMID:23200852
Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation., PMID:20795789
Transcriptomic signature of cell lines isolated from canine mammary adenocarcinoma metastases to lungs., PMID:20145299
Excessive ovarian stimulation up-regulates the Wnt-signaling molecule DKK1 in human endometrium and may affect implantation: an in vitro co-culture study., PMID:19955106
Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro., PMID:14760084
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer., PMID:14517837
Role of DDC-4/sFRP-4, a secreted frizzled-related protein, at the onset of apoptosis in mammary involution., PMID:12728251
For research use only. Not for human or drug use.
