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Anti-Mouse IL23R Polyclonal Antibody

Catalog #:   PMJ03701 Specific References (93) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q8K4B4
Overview

Catalog No.

PMJ03701

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL23R (Ser31-Ser316).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Interleukin-23 receptor (IL-23 receptor) (IL-23R)

Purification

Purified by antigen affinity column.

Accession

Q8K4B4

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL23R antibody (PMJ03701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 36 kDa
    Observed MW: 36 kDa
References

Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates., PMID:40502981

Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates., PMID:40502981

Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling., PMID:40434646

Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling., PMID:40434646

A hybrid protocol for peptide development: integrating deep generative models and physics simulations for biomolecular design targeting IL23R/IL23., PMID:40419055

A hybrid protocol for peptide development: integrating deep generative models and physics simulations for biomolecular design targeting IL23R/IL23., PMID:40419055

Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study., PMID:40297579

Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study., PMID:40297579

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis., PMID:40091833

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis., PMID:40091833

The IL-23R and Its Genetic Variants: A Hitherto Unforeseen Bridge Between the Immune System and Cancer Development., PMID:39796684

The IL-23R and Its Genetic Variants: A Hitherto Unforeseen Bridge Between the Immune System and Cancer Development., PMID:39796684

Preclinical proof of principle for orally delivered Th17 antagonist miniproteins., PMID:38936360

Preclinical proof of principle for orally delivered Th17 antagonist miniproteins., PMID:38936360

BATF-dependent Th17 cells act through the IL-23R pathway to promote prostate adenocarcinoma initiation and progression., PMID:38833676

BATF-dependent Th17 cells act through the IL-23R pathway to promote prostate adenocarcinoma initiation and progression., PMID:38833676

Insights into Therapeutic Response Prediction for Ustekinumab in Ulcerative Colitis Using an Ensemble Bioinformatics Approach., PMID:38791570

Insights into Therapeutic Response Prediction for Ustekinumab in Ulcerative Colitis Using an Ensemble Bioinformatics Approach., PMID:38791570

Identification of the grass carp interleukin-23 receptor and its proinflammatory role in intestinal inflammation., PMID:38521334

Identification of the grass carp interleukin-23 receptor and its proinflammatory role in intestinal inflammation., PMID:38521334

Isoprinosine as a foot-and-mouth disease vaccine adjuvant elicits robust host defense against viral infection through immunomodulation., PMID:38510965

Isoprinosine as a foot-and-mouth disease vaccine adjuvant elicits robust host defense against viral infection through immunomodulation., PMID:38510965

An Oral Interleukin-23-Receptor Antagonist Peptide for Plaque Psoriasis., PMID:38324484

An Oral Interleukin-23-Receptor Antagonist Peptide for Plaque Psoriasis., PMID:38324484

Secretion and surface display of binders of IL-23/IL-17 cytokines and their receptors in Lactococcus lactis as a therapeutic approach against inflammation., PMID:37619953

Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts., PMID:37367825

Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts., PMID:37367825

Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes., PMID:37208328

Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes., PMID:37208328

Single nucleotide polymorphisms in ADAM17, IL23R and SLCO1C1 genes protect against infliximab failure in adults with Crohn's disease., PMID:36621146

Angiotensin II-induced a steeper blood pressure elevation in IL-23 receptor-deficient mice: Role of interferon-γ-producing T cells., PMID:36241706

Angiotensin II-induced a steeper blood pressure elevation in IL-23 receptor-deficient mice: Role of interferon-γ-producing T cells., PMID:36241706

Synoviocytes and skin fibroblasts show opposite effects on IL-23 production and IL-23 receptor expression during cell interactions with immune cells., PMID:36088336

Synoviocytes and skin fibroblasts show opposite effects on IL-23 production and IL-23 receptor expression during cell interactions with immune cells., PMID:36088336

MiR-146b-5p regulates IL-23 receptor complex expression in chronic lymphocytic leukemia cells., PMID:35819446

MiR-146b-5p regulates IL-23 receptor complex expression in chronic lymphocytic leukemia cells., PMID:35819446

The Inflammatory Factor SNP May Serve as a Promising Biomarker for Acitretin to Alleviate Secondary Failure of Response to TNF-a Monoclonal Antibodies in Psoriasis., PMID:35814239

The Inflammatory Factor SNP May Serve as a Promising Biomarker for Acitretin to Alleviate Secondary Failure of Response to TNF-a Monoclonal Antibodies in Psoriasis., PMID:35814239

IL-23 plays a significant role in the augmentation of particulate matter-mediated allergic airway inflammation., PMID:35801505

IL-23 plays a significant role in the augmentation of particulate matter-mediated allergic airway inflammation., PMID:35801505

Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy., PMID:35482921

Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy., PMID:35482921

Biomarkers of disease progression in people with psoriasis: a scoping review., PMID:35482474

Biomarkers of disease progression in people with psoriasis: a scoping review., PMID:35482474

Allergic airway inflammation induces upregulation of the expression of IL-23R by macrophages and not in CD3 + T cells and CD11c+F4/80- dendritic cells of the lung., PMID:35475923

Allergic airway inflammation induces upregulation of the expression of IL-23R by macrophages and not in CD3 + T cells and CD11c+F4/80- dendritic cells of the lung., PMID:35475923

Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis., PMID:35455757

Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis., PMID:35455757

B cell depletion treatment decreases Th17 cells in patients with rheumatoid arthritis., PMID:34740842

B cell depletion treatment decreases Th17 cells in patients with rheumatoid arthritis., PMID:34740842

Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients., PMID:34484186

Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients., PMID:34484186

Contribution of mycobiota to the pathogenesis of spondyloarthritis., PMID:34166798

Contribution of mycobiota to the pathogenesis of spondyloarthritis., PMID:34166798

Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients., PMID:34070522

Bovine neonate is deficient in innate immunity at birth., PMID:33640760

Bovine neonate is deficient in innate immunity at birth., PMID:33640760

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors., PMID:33243781

Cell immunocapture microfluidic chip based on high-affinity recombinant protein binders., PMID:33161292

Cell immunocapture microfluidic chip based on high-affinity recombinant protein binders., PMID:33161292

Brain-homing CD4+ T cells display glucocorticoid-resistant features in MS., PMID:33037101

Brain-homing CD4+ T cells display glucocorticoid-resistant features in MS., PMID:33037101

IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE., PMID:32817415

Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373

Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373

Optimization of a High-Throughput Cell-Based Screening Strategy to Identify Small-Molecule Inhibitors of IL-23 Signaling., PMID:32484379

Optimization of a High-Throughput Cell-Based Screening Strategy to Identify Small-Molecule Inhibitors of IL-23 Signaling., PMID:32484379

IL-15 and IL-23 synergize to trigger Th17 response by CLA+ T cells in psoriasis., PMID:32476200

IL-15 and IL-23 synergize to trigger Th17 response by CLA+ T cells in psoriasis., PMID:32476200

Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway., PMID:32410846

Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway., PMID:32410846

Guselkumab in the treatment of moderate-to-severe plaque psoriasis., PMID:32314622

Guselkumab in the treatment of moderate-to-severe plaque psoriasis., PMID:32314622

Interleukin 23 and autoimmune diseases: current and possible future therapies., PMID:32215665

Interleukin 23 and autoimmune diseases: current and possible future therapies., PMID:32215665

The role of the interleukin-23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis., PMID:32022950

The role of the interleukin-23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis., PMID:32022950

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420

Interleukin-23 pathway at the enthesis: The emerging story of enthesitis in spondyloarthropathy., PMID:31957051

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation., PMID:31548399

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation., PMID:31548399

RORγT is overexpressed in iNKT and γδ T cells during relapse in relapsing-remitting multiple sclerosis., PMID:31505409

Human IL-23R Cytokine-Binding Homology Region-Fc Fusion Protein Ameliorates Psoriasis via the Decrease of Systemic Th17 and ILC3 Cell Responses., PMID:31454926

Human IL-23R Cytokine-Binding Homology Region-Fc Fusion Protein Ameliorates Psoriasis via the Decrease of Systemic Th17 and ILC3 Cell Responses., PMID:31454926

Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies., PMID:31324145

Gene expression profile of human T cells following a single stimulation of peripheral blood mononuclear cells with anti-CD3 antibodies., PMID:31324145

Engineered Lactococcus lactis Secreting IL-23 Receptor-Targeted REX Protein Blockers for Modulation of IL-23/Th17-Mediated Inflammation., PMID:31137908

Engineered Lactococcus lactis Secreting IL-23 Receptor-Targeted REX Protein Blockers for Modulation of IL-23/Th17-Mediated Inflammation., PMID:31137908

An emerging role of interleukin-23 in rheumatoid arthritis., PMID:31072166

An emerging role of interleukin-23 in rheumatoid arthritis., PMID:31072166

Critical role of interleukin-23 in development of asthma promoted by cigarette smoke., PMID:31020341

Critical role of interleukin-23 in development of asthma promoted by cigarette smoke., PMID:31020341

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Mouse IL23R Polyclonal Antibody [PMJ03701]
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