Catalog No.
PMG45101
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse CHIT1 (Lys23-Leu383).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)
Purification
Purified by antigen affinity column.
Accession
Q9D7Q1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories., PMID:40046342
Thyroid Function and Morphology in Gaucher Disease: Exploring the Endocrine Implications., PMID:39769400
Natalizumab promotes anti-inflammatory and repair effects in multiple sclerosis., PMID:38527011
A Brazilian Rare-Disease Center's Experience with Glucosylsphingosine (lyso-Gb1) in Patients with Gaucher Disease: Exploring a Novel Correlation with IgG Levels in Plasma and a Biomarker Measurement in CSF., PMID:38474117
A child with polyarthritis and chronic lung disease: a case report of ataxia-telangiectasia., PMID:37667293
Plasma levels of multiple cardiovascular- and inflammation-related proteins analysed for associations with disease activity and anti-cyclic citrullinated peptide status in active early rheumatoid arthritis., PMID:36995323
Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis., PMID:35370755
Duplication mutation in CHIT1 gene is associated with poor response to medical therapy in patients affected with filarial chyluria., PMID:34621114
Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers., PMID:32849633
Use of glycerol and propylene glycol as additives in heat-treated goat colostrum., PMID:31882214
Biomarkers and newer laboratory investigations in the diagnosis of sepsis., PMID:31497788
Sheep and goats raised in mixed flocks have diverse immune status around parturition., PMID:31255264
Clinical Significance of Serum Chitotriosidase Level in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease., PMID:31092718
NOD2 expression, DNA damage and oxido-inflammatory status in atopic bronchial asthma: Exploring their nexus to disease severity., PMID:29572197
Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months., PMID:29305734
The Role of Fungi in the Etiology of Multiple Sclerosis., PMID:29085329
Does 24bp Duplication of Human CHIT1 Gene (Chitotriosidase1) Predispose to Filarial Chyluria? A Case-Control Study., PMID:27790506
Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis., PMID:27787906
Development of anti-velaglucerase alfa antibodies in clinical trial-treated patients with Gaucher disease., PMID:27282565
Enzyme replacement therapy with taliglucerase alfa: 36-month safety and efficacy results in adult patients with Gaucher disease previously treated with imiglucerase., PMID:27102949
Successful within-patient dose escalation of olipudase alfa in acid sphingomyelinase deficiency., PMID:26049896
Seven-year safety and efficacy with velaglucerase alfa for treatment-naïve adult patients with type 1 Gaucher disease., PMID:25903392
Velaglucerase alfa (VPRIV) enzyme replacement therapy in patients with Gaucher disease: Long-term data from phase III clinical trials., PMID:25801797
Safety and efficacy results of switch from imiglucerase to velaglucerase alfa treatment in patients with type 1 Gaucher disease., PMID:25776130
The effect of colostrum source (goat vs. sheep) and timing of the first colostrum feeding (2h vs. 14h after birth) on body weight and immune status of artificially reared newborn lambs., PMID:25468691
Determination of chitinases family during osteoclastogenesis., PMID:24440516
Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis., PMID:24212238
From goat colostrum to milk: physical, chemical, and immune evolution from partum to 90 days postpartum., PMID:24183682
Chitotriosidase is a biomarker for the resistance to World Trade Center lung injury in New York City firefighters., PMID:23744081
Association of genetic variation in chitotriosidase with atopy in Korean children., PMID:23706714
Extreme stability of chitotriosidase in cerebrospinal fluid makes it a suitable marker for microglial activation in clinical trials., PMID:22785399
Effects of induced parturition in goats on immunoglobulin G and chitotriosidase activity in colostrum and plasma and on plasma concentrations of prolactin., PMID:21288684
Increased cerebrospinal fluid chitotriosidase index in patients with multiple sclerosis., PMID:19925532
Effect of colostrum immunoglobulin concentration on immunity in Majorera goat kids., PMID:19307651
Treatment of Fabry disease with different dosing regimens of agalsidase: effects on antibody formation and GL-3., PMID:18424138
Effect of treatment on biclonal gammopathy associated with Gaucher disease., PMID:17879146
Plasma chitotriosidase in male Fabry patients: a marker for monitoring lipid-laden macrophages and their correction by enzyme replacement therapy., PMID:16765076
Assessment of relations between clinical outcome of ischemic stroke and activity of inflammatory processes in the acute phase based on examination of selected parameters., PMID:15956787
Type I Gaucher disease with severe skeletal destruction, extraosseous extension, and monoclonal gammopathy., PMID:15551278
Enzyme therapy of gaucher disease: clinical and biochemical changes during production of and tolerization for neutralizing antibodies., PMID:12667990
[Gaucher's disease ]., PMID:12360743
Prospective study of neurological responses to treatment with macrophage-targeted glucocerebrosidase in patients with type 3 Gaucher's disease., PMID:9382473
For research use only. Not for human or drug use.
